| Publication Type |
Journal Article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Bastiani, Michael; Bandyopadhyay, Pradip K.; Olivera, Baldomero M.; Golic, Kent G. |
| Other Author |
Rong, Yikang S.; Titen, Simon W.; Xie, Heng B.; Golic, Mary M.; Brodsky, Michael; Rubin, Gerald M. |
| Title |
Targeted mutagenesis by homologous recombination in D. melanogaster |
| Date |
2002 |
| Description |
We used a recently developed method to produce mutant alleles of five endogenous Drosophila genes, including the homolog of the p53 tumor suppressor. Transgenic expression of the FLP site-specific recombinase and the I-SceI endonuclease generates extrachromosomal linear DNA molecules in vivo. |
| Type |
Text |
| Publisher |
Cold Spring Harbor Lab Press |
| First Page |
1568 |
| Last Page |
1581 |
| Subject |
Mutations; Drosophila; Gene targeting |
| Language |
eng |
| Bibliographic Citation |
Rong, Y. S., Titen, S. W., Xie, H. B., Golic, M. M., Bastiani, M., Bandyopadhyay, P., Olivera, B. M., Brodsky, M., Rubin, G. M., & Golic, K. G. (2002). Targeted mutagenesis by homologous recombination in D. melanogaster. Gene & Development, 16, 1568-81. |
| Rights Management |
(c) Cold Spring Harbor Laboratory Press-CSHL Press |
| Format Medium |
application/pdf |
| Format Extent |
395,173 bytes |
| Identifier |
ir-main,6447 |
| ARK |
ark:/87278/s61j9v1j |
| Setname |
ir_uspace |
| ID |
703277 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s61j9v1j |
