Targeted mutagenesis by homologous recombination in D. melanogaster

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Publication Type Journal Article
School or College College of Science
Department Biology
Creator Bastiani, Michael; Bandyopadhyay, Pradip K.; Olivera, Baldomero M.; Golic, Kent G.
Other Author Rong, Yikang S.; Titen, Simon W.; Xie, Heng B.; Golic, Mary M.; Brodsky, Michael; Rubin, Gerald M.
Title Targeted mutagenesis by homologous recombination in D. melanogaster
Date 2002
Description We used a recently developed method to produce mutant alleles of five endogenous Drosophila genes, including the homolog of the p53 tumor suppressor. Transgenic expression of the FLP site-specific recombinase and the I-SceI endonuclease generates extrachromosomal linear DNA molecules in vivo.
Type Text
Publisher Cold Spring Harbor Lab Press
First Page 1568
Last Page 1581
Subject Mutations; Drosophila; Gene targeting
Language eng
Bibliographic Citation Rong, Y. S., Titen, S. W., Xie, H. B., Golic, M. M., Bastiani, M., Bandyopadhyay, P., Olivera, B. M., Brodsky, M., Rubin, G. M., & Golic, K. G. (2002). Targeted mutagenesis by homologous recombination in D. melanogaster. Gene & Development, 16, 1568-81.
Rights Management (c) Cold Spring Harbor Laboratory Press-CSHL Press
Format Medium application/pdf
Format Extent 395,173 bytes
Identifier ir-main,6447
ARK ark:/87278/s61j9v1j
Setname ir_uspace
ID 703277
Reference URL https://collections.lib.utah.edu/ark:/87278/s61j9v1j