Publication Type |
Journal Article |
School or College |
College of Science; School of Medicine |
Department |
Oncological Sciences; Biology; Human Genetics |
Program |
Institute of Human Genetics; Howard Hughes Medical Institute (HHMI) |
Creator |
Capecchi, Mario R. |
Other Author |
Esther, Charles R.; Howard, Tom E.; Zhou, Yudong; Marrero, Mario B.; Bernstein, Kenneth E. |
Title |
Lessons from angiotensin-converting enzyme-deficient mice. |
Date |
1991-11-01 |
Description |
Mice which lack ACE have low systolic blood pressure, reduced male fertility and a renal abnormality characterized by medullary hypoplasia and the inability to concentrate urine. The diverse phenotypes caused by inactivation of a single gene emphasize the many functional roles of ACE and the renin-qngiotensin system. |
Type |
Text |
Publisher |
Rapid Science Publichers |
Volume |
5 |
Issue |
6 |
First Page |
463 |
Last Page |
467 |
Subject |
Blood Pressure; Cell Line;Fertility; Kidney; Testis |
Subject MESH |
Mice, Inbred Strains; Peptidyl-Dipeptidase A; Transcription, Genetic |
Language |
eng |
Bibliographic Citation |
Curr Opin Nephrol Hypertens. 1996 Nov;5(6):463-7. Esther CR Jr, Howard TE, Zhou Y, Capecchi MR, arrero MB, Bernstein KE. Lessons from angiotensin-converting enzyme-deficient mice. |
Rights Management |
copyright © 1995 Rapid Science Publishers. All Rights Reserved. |
Format Medium |
application/pdf |
Identifier |
ir-main,496 |
ARK |
ark:/87278/s6pn9q9d |
Setname |
ir_uspace |
ID |
706851 |
Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6pn9q9d |