Lessons from angiotensin-converting enzyme-deficient mice.

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Publication Type Journal Article
School or College College of Science; School of Medicine
Department Oncological Sciences; Biology; Human Genetics
Program Institute of Human Genetics; Howard Hughes Medical Institute (HHMI)
Creator Capecchi, Mario R.
Other Author Esther, Charles R.; Howard, Tom E.; Zhou, Yudong; Marrero, Mario B.; Bernstein, Kenneth E.
Title Lessons from angiotensin-converting enzyme-deficient mice.
Date 1991-11-01
Description Mice which lack ACE have low systolic blood pressure, reduced male fertility and a renal abnormality characterized by medullary hypoplasia and the inability to concentrate urine. The diverse phenotypes caused by inactivation of a single gene emphasize the many functional roles of ACE and the renin-qngiotensin system.
Type Text
Publisher Rapid Science Publichers
Volume 5
Issue 6
First Page 463
Last Page 467
Subject Blood Pressure; Cell Line;Fertility; Kidney; Testis
Subject MESH Mice, Inbred Strains; Peptidyl-Dipeptidase A; Transcription, Genetic
Language eng
Bibliographic Citation Curr Opin Nephrol Hypertens. 1996 Nov;5(6):463-7. Esther CR Jr, Howard TE, Zhou Y, Capecchi MR, arrero MB, Bernstein KE. Lessons from angiotensin-converting enzyme-deficient mice.
Rights Management copyright © 1995 Rapid Science Publishers. All Rights Reserved.
Format Medium application/pdf
Identifier ir-main,496
ARK ark:/87278/s6pn9q9d
Setname ir_uspace
ID 706851
Reference URL https://collections.lib.utah.edu/ark:/87278/s6pn9q9d