Pendular Nystagmus and Ocular Motor Signs in MS

Update item information
Identifier Pendular_nystagmus_and_ocular_motor_dysfunction_in_MS
Title Pendular Nystagmus and Ocular Motor Signs in MS
Subject Pendular Nystagmus; Jerk Nystagmus; Gaze Evoked Nystagmus; Abnormal Saccades
Creator Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine
Description This is a 30-year-old man with a 15 year history of multiple sclerosis. For the last 12 months, he experienced horizontal oscillopsia. On examination, there were ocular motor abnormalities including gaze-evoked nystagmus, saccadic smooth pursuit, and hypermetric saccades which were attributable to his posterior fossa demyelinating disease. Additionally, there was horizontal pendular nystagmus, and this abated briefly with the termination of saccades and with blinks, both of which commonly suppress pendular nystagmus (albeit transiently). His vision was 20/100 OU with 0/10 HRR plates OU with temporal pallor OU. Because pendular nystagmus is commonly seen in MS patients, it has been suggested that the nystagmus might result from a prolonged response time for visual processing, supported by the fact that nystagmus is commonly more intense in the eye with poorer vision. However, pendular nystagmus doesn't change with visual feedback removed, and inducing visual delays by itself is not capable of causing the oscillations seen in MS. Therefore, it's likely that instability in the neural integrator (gaze holding machinery) plays a significant role in many cases, and his severe posterior fossa disease was likely to have contributed to neural integrator dysfunction.
Imaging Number of Videos and legend for each: 1, Patient with pendular and jerk nystagmus due to MS
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2017
Type Image/MovingImage
Format video/mp4
Relation is Part of NOVEL: Neuro-ophthalmology Virtual Education Library Examination Collection
Rights Management Copyright 2017. For further information regarding the rights to this collection, please visit:
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah, 10 N 1900 E, SLC, UT 84112-5890
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
Language eng
ARK ark:/87278/s6nc9v0z
Setname ehsl_novel_gold
Date Created 2017-07-26
Date Modified 2021-05-06
ID 1256241
Reference URL