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Show 204 LITERATURE ABSTRACTS Dr. S. A. Laure, Gartner Library, Montefiore Medical Center, 111 E. 210th St. Bronx, NY 10467.] A 37-year-old man originally from Cuba and raised in Jamaica presented with skin lesions; biopsy was consistent with cutaneous T cell lymphoma. Four years later, biopsy of a mass in the left ethmoid and orbit revealed a similar lymphoma. The authors state that "this is the first report of orbital involvement in systemic adult T-cell leukemia/lymphoma ... the etiologic agent [of which] is the human T-cell leukemia virus-I (HTLV-I), the first retrovirus demonstrated to induce cancer in humans." Lyn A. Sedwick, M.D. Uremic Optic Neuropathy. Knox DL, Hanneken AM, Hollows FC, Miller NR, Schick HL, Gonzales WL. Arch Ophtha/mo/1988;106:50-4 Oan). [Reprint requests to Dr. D. L. Knox, The Wilmer Institute, The Johns Hopkins Hospital, Baltimore, MD 21205.] Six patients with renal failure are discussed in detail who demonstrated subacute visual loss and disc edema that was reversible in some cases with dialysis and/or corticosteroids. There were confounding variables in nearly every case (hypertension, sickle cell disease, IgA myeloma, anemia) but there did seem to be something special relating visual loss and disc edema to the uremia itself in these patients. The authors remark that such patients may have heretofore been felt to have ischemic optic neuropathy and were not treated, but they note that their cases did exceedingly well with treatment. As they say, "the most important conclusion from the present series is the need to recognize this syndrome and consider it a therapeutically urgent situation." Lyn A. Sedwick, M.D. A~ute Idiopathic Blind Spot Enlargement. A Big Bltnd Spot Syndrome Without Optic Disc Edema. Fletcher WA, Imes RK, Goodman D, Hoyt WF. Arch Ophtha/mol 1988;106:44-9 Oan). [Reprint requests to Dr. W. F. Hoyt, Department of Neurosurgery, Neuro-ophthalmology Unit, 876 Moffit Hospital, University of California, San Francisco, CA 94143.] Seven patients were reviewed who had enl. m"",rl blind spots on visual field testing but essen-edema and, in five cases, without afferent pupillary defect. Various studies were performed including "multifocal electroretinography," which suggested dysfunction of the peripapillary retina. These patients, who frequently complained of positive visual phenomena, can be distinguished from those with optic nerve edema, "big blind spot syndrome" on the basis of their symptoms; however, both groups usually have resolution of signs and symptoms on follow-up examination. Lyn A. Sedwick, M.D. Clinical Features, Laboratory Investigations, and Survival in Ocular Reticulum Cell Sarcoma. Freeman LN, Schachat AP, Knox OL, Michels RG, Green WR. Ophthalmology 1987;94:1631-9 (Dec). [Reprint requests to Dr. A. P. Schachat, Ocular Oncology Service, Wilmer 200, The Johns Hopkins Medical Institutions, Baltimore, MD 21205.] This review from the eye pathology laboratory at Wilmer identified 32 cases of pathologically verified intraocular reticulum cell sarcoma. Clinical information and follow-up data were obtained for all patients. Almost all had posterior and/or anterior uveitis or chorioretinitis. The mean age at onset was 58 years, and a diagnosis of ocular involvement was made by vitreous biopsy in 18 patients. Mean survival after diagnosis was 35 months, and computerized tomographic scanning and spinal tap were the most revealing systemic tests. Various therapies were tried, but radiation was the most popular and efficacious. The literature was reviewed, and two nice fundus photos, albeit black and white, were included in the article. Lyn A. Sedwick, M.D. Carotid Artery Disease. A Therapeutic Enigma. Becker WL, Burde RM. Arch Ophthalmol 1988;106:34-9 (Jan). [No reprint information given.] . T.his .editorial-like article nicely reviews current mdlcahons, good and bad, for carotid endarterectomy, as well as the diagnostic tests available and alternative therapies. Medical testing for risk factors of arteriosclerosis is almost always advised, a~d duplex scanning of the carotids may be conSidered for patients who are candidates for endarterectomy. Much caution is sounded in this article regarding the need to select patients whose risk from surgery is less than the expected benefit. Lyn A. Sedwick, M.D. |
