Sensation consists of various modalities, which tend to travel in one of two pathways. The Anterolateral System also known as the Spinothalamic Tract carries pain and temperature. The Dorsal Column-Medical Lemniscus Pathway carries vibration, joint position, and fine 2-point discrimination. Light or crude touch travel in both pathways. The video demonstrates both grossly and with diagrams the difference in the two pathways as they travel to the cortex emphasizing where they cross to the opposite side. Somatotopic cortical representation and blood supply are introduced.