| Publication Type |
journal article |
| School or College |
College of Science |
| Department |
Biology |
| Creator |
Potts, Wayne K.; Granger, Donald Lee |
| Other Author |
McClelland, Erin E. |
| Title |
Major histocompatibility complex-dependent susceptibility to Cryptococcus neoformans in mice |
| Date |
2003 |
| Description |
To evaluate the role of major histocompatibility complex (MHC) genes in the resistance to Cryptococcus neoformans, we conducted infection experiments in MHC-congenic strains of mice. Significant MHC-dependent susceptibility differences were found among homozygotes and heterozygotes. This study is the first experimental demonstration of MHC-dependent susceptibility to C. neoformans infections in mice and indicates that MHC genes can be important in host resistance. |
| Type |
Text |
| Publisher |
American Society for Microbiology |
| Volume |
71 |
| Issue |
8 |
| First Page |
4815 |
| Last Page |
4817 |
| Subject |
MHC-congenic; Host resistance; Infection |
| Dissertation Institution |
University of Utah |
| Language |
eng |
| Bibliographic Citation |
McClelland, E. E., Granger, D. L., & Potts, W. K. (2003). Major histocompatibility complex-dependent susceptibility to Cryptococcus neoformans in mice. Infection and Immunity, 71(8), Aug., 4815-7. |
| Rights Management |
©American Society for Microbiology |
| Format Medium |
application/pdf |
| Format Extent |
64,357 bytes |
| Identifier |
ir-main,6010 |
| ARK |
ark:/87278/s6h428q1 |
| Setname |
ir_uspace |
| ID |
704132 |
| Reference URL |
https://collections.lib.utah.edu/ark:/87278/s6h428q1 |
