Figure 51: Lateral Medullary Lesion Causing Saccadic Dysmetria

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Identifier gold_textbook_figures_051
Title Figure 51: Lateral Medullary Lesion Causing Saccadic Dysmetria
Creator Daniel R. Gold, DO
Affiliation (DRG) Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine, Baltimore, Maryland
Description A lesion of the left lateral medulla and inferior cerebellar peduncle (ICP) will cause decreased climbing fiber inhibition of the left dorsal vermis causing simple-spike (inhibitory) discharge of Purkinje cells to increase. Increased Purkinje cell firing leads to increased inhibition of the ipsilateral (left) fastigial nucleus, with a resultant decrease in excitation of the right excitatory burst neuron/inhibitory burst neuron (EBN/IBN) pair. This will lead to less excitation of the ipsilateral (right) VIth nucleus and less inhibition of the contralateral (left) VIth nucleus, with an end result of right hypometria and left hypermetria (and ipsipulsion).
Date 2022
References Gold D. (2022). Neuro-ophthalmology and neuro-otology : a case-based guide for clinicians and scientists. Springer International Publishing AG. Retrieved September 16 2022 from https://online.statref.com/p/1057?grpAlias=.
Language eng
Format image/jpeg
Type Image
Relation is Part of Neuro-Ophthalmology and Neuro-Otology: A Case-Based Guide for Clinicians and Scientists
Collection Neuro-Ophthalmology Virtual Education Library: Dan Gold Collection: https://novel.utah.edu/Gold/
Publisher North American Neuro-Ophthalmology Society
Holding Institution Spencer S. Eccles Health Sciences Library, University of Utah
Rights Management Copyright 2016. For further information regarding the rights to this collection, please visit: https://NOVEL.utah.edu/about/copyright
ARK ark:/87278/s6gy1ptn
File Name gold_textbook_figures_051.png
Setname ehsl_novel_gold
ID 2050031
Reference URL https://collections.lib.utah.edu/ark:/87278/s6gy1ptn