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Show 210 LITERATURE ABSTRACTS Paraneoplastic Retinopathy in Malignant Melanoma. Rush JA. Am J Ophthalmol 1993;115:390-1 (Mar). [Inquiries to Dr. J. A. Rush, 508 South Habana Avenue, Suite 100, Tampa, FL 33609.] Dr. Rush reports a 50-year-old man with a I-month_ history of right axillary metastatic melanoma (primary unknown) who developed photopsia, then delayed dark adaptation. His ERGs were abnormal, and he was ultimately found to have increased titers of antibody to retina and optic nerve consistent with paraneoplastic retinopathy. He declined therapy and follow-up examination. Lyn A. Sedwick, M.D. The Relationship Between Static Perimetry and the Relative Afferent Pupillary Defect. Kardon RH, Haupert CL, Thompson HS. Am J Ophthalmol 1993;115:351-6 (Mar). [Reprint requests to Dr. R. H. Kardon, Department of Ophthalmology, University of Iowa Hospital, Iowa City, IA 52242.] The authors examine the amount of Goldmann and Humphrey (program 30-2) visual field loss in one eye versus the other and correlate it to the strength of the afferent pupillary defect measured with neutral density filters. They found a linear relationship that was only moderate overall, although the slope for individual diagnoses did steepen, especially for compressive optic neuropathy and intracranial hypertension. They discuss the clinical implications of their results and compared them to other similar studies. Lyn A. Sedwick, M.D. An Unusual Case of Giant Cell Arteritis. Shah P, Murray PI, Harry J. Am JOphthalmolI993;115:393---4 (Mar). [Inquiries to Dr. P. I. Murray, Academic Unit, Birmingham and Midland Eye Hospital, Church Street, Birmingham B3 2NS, United Kingdom.] Dr. Shah and colleagues present a 41-year-old Pakistani lady with headaches, episodic blurred vision, and a sedimentation rate of 10 (type not given) but a positive temporal artery biopsy consistent with temporal arteritis. (Skeptics note: Pathologic photographs show disruption of inter- I Clin Neuro-ophtlwlmol. Vol. 13. No.3. 1993 nal elastic membrane and multinucleated giant cells). She responded to corticosteroid therapy. The authors comment on this (highly) unusual case of temporal arteritis. Lyn A. Sedwick, M.D. Visual Loss After Retrogasserian Glycerol Injection. Kalin NS, Wulc AE, Piccone MR, Casey K. Am J OphthalmolI993;115:396-8 (Mar). [Inquiries to Dr. A. E. Wulc, Oculoplastic and Orbital Service, Department of Ophthalmology, University of Pennsylvania, Scheie Eye Institute, 51 North 39th Street, Philadelphia, PA 19104.] A patient underwent percutaneous retrogasserian glycerol injection for left facial pain but 1 hour postoperatively reported loss of vision on the same side. The eye was proptotic, orbit taut, and she had complete external ophthalmoplegia. Canthotomy was performed when vision deteriorated to no light perception. Ultimately, vision partially returned. The authors speculate that the glycerol entered the orbit from the inferior orbital fissure via the pterygopalatine fossa. A serious complication of a relatively safe procedure. Lyn A. Sedwick, M.D. Visual Prognosis in Autosomal Dominant Optic Atrophy (Kjer Type). Elliott 0, Traboulsi EI, Maumenee IH. Am J Ophthalmol 1993;115:360-7 (Mar). [Reprint requests to Dr. I. H. Maumenee, Johns Hopkins Center for Hereditary Eye Diseases, Maumenee Building, Room 321, Johns Hopkins Hospital, 600 N. Wolfe St., Baltimore, MD 21205.] .This s~dy includes 25 patients from 3 pedigrees ~lth dommant optic atrophy with follow-up rang109 from 5 to 40 years. Median initial visual acuity was 20/60, and median final visual acuity was 201 80. Specific visual characteristics of all patients are clearly presented in a table, and results from this study are compared to previous studies of similar patients. A good reference on this subject. Lyn A. Sedwick, M.D. |