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Show LITERATURE ABSTRACTS 213 Leber's Hereditary Optic Neuropathy. Clinical Manifestations of the 14484 Mutation. Johns DR, Heher KL, Miller NR, Smith KH. Arch Ophthalmol 1993;111:495-8 (Apr). [Reprint requests to Dr. D. R. Johns, Department of Neurology, The Johns Hopkins Hospital, Meyer 6-119, 600 North Wolfe Street, Baltimore, MD 21287-7619.] This article describes 19 patients with Leber's from 17 pedigrees who harbored a 14884 mutation. Clinical characteristics of these patients, who seem to have a better chance for spontaneous recovery of vision than the average Leber's patient, are described. Lyn A. Sedwick, M.D. Management of Combined Penetrating Intraorbital and Intracranial Trauma. Michon JJ, Miller NR. Arch Ophthalmol 1993;111:438--9 (Apr). [Reprint requests to Dr. J. J. Michon, Doheny Eye Institute, 1450 San Pablo Street, Los Angeles, CA 90033.] An 11-year-old boy with an unusual penetrating injury to orbit with potential extension intracranially is discussed. The exact surgical sequence, i.e., anesthesia, presence of neurosurgeons, removal of the metal rod, and postoperative care is described. This very fortunate patient did quite well with this optimal management. Lyn A. Sedwick, M.D. Effect of Transposition Surgery on Rectus Muscle Paths by Magnetic Resonance Imaging. Miller JM, Derner JL, Rosenbaum AL. Ophthalmology 1993; 100:475-87 (Apr). [Reprint requests to Dr. J. M. Miller, Smith-Kettlewell Institute, 2232 Webster Street, San Francisco, CA 94115.] The authors evaluated five patients who had muscle transposition surgery with surface coil magnetic resonance imaging pre- and postoperatively. They found that "even aggressive transposition surgery has less effect on the paths of rectus muscle bellies than would be expected under the conventional model." There are many detailed mechanical drawings to diagram their findings. Lyn A. Sedwick, M.D. Extraocular Muscle Involvement in Sarcoidosis. Cornblath WT, Elner V, Rolfe M. Ophthalmology 1993;100:501-5 (Apr). [Address correspondence to Dr. W. T. Cornblath, Department of Ophthalmology, W. K. Kellogg Eye Center, 1000 Wall Street, Ann Arbor, MI48105.] A 15-year-old boy with bilateral painful ophthalmoplegia had all extraocular muscles enlarged on computed tomographic scanning. Extraocular muscle biopsy showed granuloma consistent with sarcoidosis, and transbronchial biopsy was positive as well. A unique and previously unreported initial presentation of sarcoidosis. Lyn A. Sedwick, M.D. Visual Prognosis in Giant Cell Arteritis. Aiello PD, Trautmann JC, McPhee n, Kunselman AR, Hunder GG. Ophthalmology 1993;100:35~5 (Apr). [Reprint requests to Dr. J. C. Trautmann, Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.] All patients at Mayo Clinic with a diagnosis of giant-cell arteritis over a 5-year period, from 1980 to 1984 inclusive, were reviewed. Of 245 patient, 34 (14%) lost vision permanently because of giantcell arteritis. In 32 patients, visual loss occurred prior to therapy, and in 2 patients, after starting therapy. In 3, vision worsened, and in 5, vision improved after therapy. They concluded that visualloss or progression of previous visual loss was rare after initiation of appropriate therapy for giant- cell arteritis. Lyn A. Sedwick, M.D. Transesophageal Echocardiography in the Diagnosis of Branch Retinal Artery Obstruction. Wisotsky BI, Engel HM. Am JOphthalmoI1993;115: 653-6 (May). [Reprint requests to Dr. B. J. Wisotsky, Department of Ophthalmology, Albert Einstein College of Medicine, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467.] Two young patients with branch retinal artery occlusion (ages 28 and 19) were exhaustively studied for a possible source of emboli. Only transesophageal echocardiography disclosed a patent foramen ovale in each. This type of echocardio- JClin Neuro-ophthalmol, Vol. 13, No.3, 1993 |
