ALP-enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans

Update item information
Publication Type Journal Article
School or College College of Science
Department Biology
Creator Beckerle, Mary C.
Other Author Han, Hsaio-Fen
Title ALP-enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans
Date 2009
Description Mutations that affect the Z-disk-associated ALP-Enigma proteins have been linked to human muscular and cardiac diseases. Despite their clear physiological significance for human health, the mechanism of action of ALP-Enigma proteins is largely unknown. In Caenorhabditis elegans, the ALP-Enigma protein family is encoded by a single gene, alp-1; thus C. elegans provides an excellent model to study ALP-Enigma function. Here we present a molecular and genetic analysis of ALP-Enigma function in C. elegans.
Type Text
Publisher American Society for Cell Biology
Volume 20
Issue 9
First Page 2361
Last Page 2370
Subject Actin; Caenorhabditis elegans; Contractility; alp-1 mutants; Z-disks; Kettin
Subject LCSH Cytoskeletal proteins; Muscle cells; Nematodes -- Physiology
Language eng
Bibliographic Citation Han, H.-F., & Beckerle, M. C. (2009). ALP-enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans. Molecular Biology of the Cell, 20(9), 2361-70.
Rights Management (c)American Society for Cell Biology http://www.molbiolcell.org/
Format Medium application/pdf
Format Extent 542,401 bytes
Identifier ir-main,7550
ARK ark:/87278/s6bg36c0
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2021-05-06
ID 704698
Reference URL https://collections.lib.utah.edu/ark:/87278/s6bg36c0