Pallidotomy in advanced Parkinson's disease

Update item information
Publication Type Journal Article
School or College School of Medicine
Department Neurosurgery
Creator Couldwell, William T.
Other Author Grafton, Scott T.
Title Pallidotomy in advanced Parkinson's disease
Date 1995
Description To the Editor: We read with interest the comments published regarding our recent article on pallidotomy in patients with advanced Parkinson's disease (3). There seems to be confusion as to some of the technical methods used in creating the radiofrequency lesions in these patients. As noted in the Patients and Methods section, multiple lesions were created by moving the probe to achieve the ultimate overall lesion. The short radiofrequency times noted in the comments are used in performing thalamotomy by our group to titrate the size of the lesion to the clinical response. However, the lesions created in the medial pallidum in the present series of patients were large (lesioning times, 45-60 s for each probe position), as also noted by the dimensions of the lesions revealed by the follow-up MRI studies. The size and position of the lesions should target the globus pallidus internus and certainly some of the globus pallidus externus as well, given the relative size and proximity of these targets (see Plate 27 [coronal] and Plate 45 [sagittal] of the Atlas for Stereotaxy of the Human Brain [2).
Type Text
Publisher Wolters Kluwer (LWW)
Volume 37
Issue 6
First Page 1234
Last Page 1235
Subject Pallidotomy; Dyskinesia
Subject LCSH Parkinson's disease -- Treatment; Globus pallidus -- Surgery
Language eng
Bibliographic Citation Couldwell, W. T., & Grafton, S. T. (1995). Pallidotomy in advanced Parkinson's disease [Letter to the editor]. Neurosurgery, 37(6), 1234-5.
Rights Management (c) Wolters Kluwer (LWW)
Format Medium application/pdf
Format Extent 103,500 bytes
Identifier ir-main,12987
ARK ark:/87278/s69601q6
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2021-05-06
ID 703244
Reference URL