Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project

Update item information
Publication Type Journal Article
School or College School of Medicine
Department Neurosurgery
Creator Schmidt, Meic H.
Other Author Chang, Susan M.; Parney, Ian F.; McDermott, Michael; Barker, Fred G.; Huang, Wei; Laws, Edward R.; Lillehei, Kevin O.; Bernstein, Mark; Brem, Henry; Sloan, Andrew E.; Berger, Mitchel
Title Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project
Date 2003
Description In many new clinical trials of patients with malignant gliomas surgical intervention is incorporated as an integral part of tumor-directed interstitial therapies such as gene therapy, biodegradable wafer placement, and immunotherapy. Assessment of toxicity is a major component of evaluating these novel therapeutic interventions, but this must be done in light of known complication rates of craniotomy for tumor resection. Factors predicting neurological outcome would also be helpful for patient selection for surgically based clinical trials. Methods. The Glioma Outcome Project is a prospectively compiled database containing information on 788 patients with malignant gliomas that captured clinical practice patterns and patient outcomes. Patients in this series who underwent their first or second craniotomy were analyzed separately for presenting symptoms, tumor and patient characteristics, and perioperative complications. Preoperative and intraoperative factors possibly related to neurological outcome were evaluated.
Type Text
Publisher American Association of Neurological Surgeons (AANS)
Volume 98
First Page 1175
Last Page 1181
Subject Perioperative complications; Neurological outcomes; Glioma Outcome Project
Subject LCSH Gliomas; Gliomas -- Treatment; Craniotomy; Craniotomy -- Complications
Language eng
Bibliographic Citation Chang, S. M., Parney, I. F., McDermott, M., Barker, F. G., Schmidt, M. H., Huang, W., Laws, E. R., Lillehei, K. O., Bernstein, M., Brem, H., Sloan, A. E., & Berger, M. (2003). Perioperative complications and neurological outcomes of first and second craniotomies among patients enrolled in the Glioma Outcome Project. Journal of Neurosurgery, 98, 1175-81.
Rights Management (c) American Association of Neurological Surgeons
Format Medium application/pdf
Format Extent 60,033 bytes
Identifier ir-main,12762
ARK ark:/87278/s68p6hw1
Setname ir_uspace
Date Created 2012-06-13
Date Modified 2013-02-28
ID 704683
Reference URL https://collections.lib.utah.edu/ark:/87278/s68p6hw1