Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2

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Publication Type Journal Article
School or College College of Science
Department Biology
Creator Jorgensen, Erik
Other Author Jung, Nadja; Wienisch, Martin; Gu, Mingyu; Rand, James B.; Müller, Sebastian L; Krause, Gerd; Klingauf, Jurgen; Haucke, Volker
Title Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2
Date 2007
Description Synaptic transmission depends on clathrin-mediated recycling of synaptic vesicles (SVs). How select SV proteins are targeted for internalization has remained elusive. Stonins are evolutionarily conserved adaptors dedicated to endocytic sorting of the SV protein synaptotagmin. Our data identify the molecular determinants for recognition of synaptotagmin by stonin 2 or its Caenorhabditis elegans orthologue UNC-41B.
Type Text
Publisher Rockefeller University Press
Volume 179
Issue 7
First Page 1497
Last Page 1510
Language eng
Bibliographic Citation Jung, N., Wienisch, M., Gu, M., Rand, J. B., Müller, S. L., Krause, G., Jorgensen, E., Klingauf, J., & Haucke, V. (2007). Molecular basis of synaptic vesicle cargo recognition by the endocytic sorting adaptor stonin 2. Journal of Cell Biology, 179(7), 1497-510.
Rights Management (c) Author(s) http://www.jcb.org/
Format Medium application/pdf
Format Extent 7,359,269 bytes
Identifier ir-main,6264
ARK ark:/87278/s63r1bk5
Setname ir_uspace
ID 707254
Reference URL https://collections.lib.utah.edu/ark:/87278/s63r1bk5