Gaze-evoked and rebound nystagmus in a cerebellar syndrome

Update item information
Identifier GEN&Rebound
Title Gaze-evoked and rebound nystagmus in a cerebellar syndrome
Subject Jerk nystagmus; End-gaze nystagmus; Gaze-evoked nystagmus; Rebound nystagmus; Cerebellar pathology
Creator Daniel R. Gold, DO, Departments of Neurology, Ophthalmology, Neurosurgery, Otolaryngology - Head & Neck Surgery, Emergency Medicine, and Medicine, The Johns Hopkins School of Medicine
Description 30-yo-man with the subacute onset of a cerebellar syndrome. After extensive evaluation and progression, it was thought that this represented an autoimmune process and there was some improvement with immunosuppression. He had a variety of cerebellar ocular motor findings, including gaze-evoked nystagmus with rebound (e.g., left-beating nystagmus in left gaze, transitioning to right-beating when he looks back to primary), saccadic smooth pursuit and failure of VOR suppression, and saccadic dysmetria. In some cases, the distinction between physiologic end point nystagmus (EPN) and pathologic gaze-evoked nystagmus (GEN) can be difficult. Findings suggestive of EPN include relatively small amplitude, fatigues, abates in ¾ eccentric position (far enough in that both eyes can view the target), and the absence of rebound nystagmus (occasionally, normal people may have a beat or two), often with a horizontal-slight torsional (towards the ipsilateral ear) component. Findings suggestive of GEN include larger amplitude, doesn't fatigue, still present in ¾ eccentric position (far enough in that both eyes can view the target), and presence of rebound or centripetal nystagmus. Centripetal nystagmus is a nystagmus in eccentric gaze, in which the fast phase beats ""centripetally"" towards primary gaze. Video shows patient with cerebellar disease demonstrating gaze-evoked and rebound nystagmus.
Publisher Spencer S. Eccles Health Sciences Library, University of Utah
Date 2016
Type Image/MovingImage
Format video/mp4
Rights Management Copyright 2016. For further information regarding the rights to this collection, please visit:
Collection Neuro-ophthalmology Virtual Education Library: NOVEL
Language eng
ARK ark:/87278/s6089dz6
Setname ehsl_novel_gold
Date Created 2016-08-30
Date Modified 2017-05-02
ID 187733
Reference URL