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TitleDescriptionSubject
1 A Comparison of Nystagmus and Saccadic Intrusions/OscillationsNystagmus can be classified into pendular and jerk waveforms, where both are generated by a slow, pathologic phase. Corrective phase (the position reset mechanism) differs. In pendular nystagmus, the eyes move back and forth with about the same velocity and amplitude, similar to that of a pendulum...Jerk Nystagmus, Flutter, Pendular Nystagmus, Square Wave Jerks, Opsoclonus,
2 Bilateral Horizontal Gaze Palsy and Oculopalatal Tremor Due to Pontine HemorrhageThis 70-yo-woman experienced headache and diplopia and was found to have a hemorrhage centrally within the dorsal pons. Months after the onset, the patient was seen in clinic and had no horizontal eye movements (pursuit, saccades, VOR) in either eye, suggestive of bilateral nuclear 6th nerve palsies...VOR HIT Abnormal, Horizontal Gaze Palsy, OMS PONS, Pendular Nystagmus, Oculopalatal
3 Congenital nystagmusPresented here are two patients with congenital nystagmus demonstrating characteristic features including: mixed pendular and jerk nystagmus (usually gaze-evoked) waveforms, stays horizontal even in vertical gaze, suppression with convergence, strabismus and a latent component (common but not always...Jerk Nystagmus, Pendular Nystagmus, Latent Nystagmus, Congenital Acquired Nystagmus
4 Elliptical Pendular Nystagmus in MSThis is a 40-yo-woman with MS and bilateral optic nerve disease who presented with a year's long history of oscillopsia, which was related to elliptical pendular nystagmus. The appearance of elliptical nystagmus is the result of out of phase horizontal and vertical components. She had a variety of p...Pendular Nystagmus, Multiple Sclerosis
5 Eye closure and oculopalatal tremorThis patient suffered a traumatic brain injury with brainstem injury resulting in damage to Mollaret's triangle and palatal tremor. Inferior olivary hypertrophy was noted on her MRI, although no vertical and/or torsional pendular nystagmus was present even when observing closely with the ophthalmosc...Pendular Nystagmus; Oculopalatal Tremor
6 Monocular horizontal pendular nystagmus in MSBoth of these patients have MS and monocular (OS) horizontal pendular nystagmus. The first patient seen in the video has normal afferent function and no evidence of optic nerve disease in either eye, while the second patient has severe OS>>OD optic nerve disease related to bouts of optic neuritis (t...Pendular Nystagmus
7 Oculopalatal tremor and internuclear ophthalmoplegia due to hemorrhagic pontine cavernomaThis is a 60-year-old woman who experienced 2 episodes of vertigo, nausea and vomiting, which was felt to be related to recurrent hemorrhage of a pontine cavernoma that was adjacent to the fourth ventricle. The cavernoma was resected, and diplopia and left facial palsy were noted after the surgery. ...Pendular Nystagmus, Oculopalatal Tremor; INO; Pons OMS; Seventh Facial Nerve
8 Oculopalatal tremor and one-and-a-half syndrome due to pontine hemorrhageThis is a 65-year-old man who was put on a blood thinner, and shortly thereafter experienced a midline pontine hemorrhage, which was more dense on the left side. Immediately afterwards, right hemiparesis and hemi-anesthesia, left lower motor neuron (LMN) facial palsy and ophthalmoparesis were noted....Pendular Nystagmus; Oculopalatal Tremor; INO; One and a Half; Pons OMS; Seventh Facial Nerve; Sixth Abducens Nerve
9 Oculopalatal tremor with prominent nystagmus, bilateral horizontal gaze palsy, and bilateral facial palsiesThis is a 50-year-old woman who experienced the acute onset of right sixth and seventh nerve palsies and left hemiparesis. Two cavernomas within the right pons (one in the region of the facial colliculus) were demonstrated by MRI. Five years after her initial presentation she developed recurrent r...Abnormal Range, Sixth Nerve Palsy, Facial Nerve, Horizontal Gaze Palsy, OMS Pons, Pendular Nystagmus, Oculopalatal
10 Oculopalatal tremor with prominent nystagmus, bilateral horizontal gaze palsy, and bilateral facial palsies Figure 1Figure 1, MRI T2 sequence demonstrating hyperintensities involving bilateral inferior olives of the medulla. This is a 50-year-old woman who experienced the acute onset of right sixth and seventh nerve palsies and left hemiparesis. Two cavernomas within the right pons (one in the region of the facia...Abnormal Range, Sixth Nerve Palsy, Facial Nerve, Horizontal Gaze Palsy, OMS Pons, Pendular Nystagmus, Oculopalatal
11 Pendular nystagmus and ocular motor signs in MSThis is a 30-year-old man with a 15 year history of multiple sclerosis. For the last 12 months, he experienced horizontal oscillopsia. On examination, there were ocular motor abnormalities including gaze-evoked nystagmus, saccadic smooth pursuit, and hypermetric saccades which were attributable to h...Pendular Nystagmus, Jerk Nystagmus, Gaze Evoked Nystagmus, Abnormal Saccades
12 Pendular nystagmus and vision lossThree patients are presented here, each with poor vision (counting fingers or worse) related to retinitis pigmentosa in one patient (Usher's syndrome) and optic neuropathy in two patients, each of whom developed pendular nystagmus after vision loss developed. Visually mediated movements normally pre...Pendular Nystagmus
13 Pendular, gaze-evoked and abducting nystagmus in MSThis is a 40-year-old woman with a history of multiple sclerosis who presented for oscillopsia. On examination, she had bilateral internuclear ophthalmoplegia (INO-adduction lag OU and abducting nystagmus OU), with a corresponding exotropia that increased in right and left gaze. She also had horiz...Jerk Nystagmus, INO, Pendular Nystagmus; Abducting Nystagmus, Gaze-Evoked Nystagmus, Cerebellar OMS
14 Pontine hemorrhage causing oculopalatal tremor and multiple cranial neuropathiesThis is a 45-yo-woman who had a dorsal pontine cavernoma that bled 2 years prior to this video. Symptoms included diplopia and oscillopsia. On examination, she had left>right facial palsies (upper and lower face from involvement of the nucleus/fascicle - i.e., lower motor neuron palsies) and sixth n...Sixth Nerve Palsy; Pons; Pendular Nystagmus; Oculopalatal Tremor
15 Subtle torsional pendular nystagmus in oculopalatal tremor (OPT)This is a 50-year-old woman who presented with imbalance, and MRI demonstrated a right cerebellar cavernous malformation. She underwent surgery to resect the malformation, and post-operatively experienced right hemiparesis and ataxia. Six months after the surgery, balance worsened and vision became ...Pendular Nystagmus; Oculopalatal Tremor
16 Subtle torsional pendular nystagmus in oculopalatal tremor (OPT) - Figure 1This is a 50-year-old woman who presented with imbalance, and MRI demonstrated a right cerebellar cavernous malformation. She underwent surgery to resect the malformation, and post-operatively experienced right hemiparesis and ataxia. Six months after the surgery, balance worsened and vision became ...Pendular Nystagmus; Oculopalatal Tremor
17 Test Your Knowledge - Monocular OscillopsiaWhich of the following associated signs is most likely to be seen in this patient presenting with oscillopsia? ; A.; Optic nerve pallor ; B.; Palatal tremor; C.; Severe unilateral cataract ; D.; Head bobbing; E.; Neurovascular contact on MR CISS/FIESTA imaging; ; A.; Correct. This patient has MS an...Pendular Nystagmus
18 Test Your Knowledge - OscillopsiaThis 65-year-old man with multiple sclerosis described that objects in front of him appear to spontaneously jump or move horizontally for the last few months. He reported that his symptoms occur independent of head movements and head impulse testing was normal. After viewing the video, what is the m...Pendular Nystagmus, Jerk Nystagmus, Abducting Nystagmus, Internuclear Ophthalmoplegia
19 Triangle of Guillain-MollaretSeen here is a schematic representation of the Gullain-Mollaret triangle (Figure 1), also referred to as the dentato-olivary pathway, reflecting the 3 points of this imaginary triangle - 1) dentate nucleus, 2) red nucleus, and 3) inferior olivary nucleus. The olive sends decussating climbing fibers ...Pendular Nystagmus; Oculopalatal Tremor
20 Vertical-Torsional Pendular Nystagmus and Convergence Spasm Due to Anti-MaTa EncephalitisThis is a 50-yo-woman with debilitating oscillopsia due to a high frequency (6 Hz) vertical-torsional pendular (quantitative eye movement recordings were performed) nystagmus. She also had intermittent double vision due to (organic) convergence spasm. Her nystagmus and spasm were thought to be relat...Mesencephalon; Pendular nystagmus; Convergence spasm
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