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Creator | Title | Description | Subject | Date |
| 201 |
 |
Olivera, Baldomero M.; Gray, William Robert | New family of Conus peptides targeted to the nicotinic acetylcholine receptor | In this work, a new family of Conus peptides, the αA-conotoxins, which target the nicotinic acetylcholine receptor, is defined. The first members of this family have been characterized from the eastern Pacific species, Conus purpurascens (the purple cone); three peptides that cause paralysis in fis... | Conotoxins; Conus peptides; Conus purpurascens; Purple cone snail | 1995 |
| 202 |
 |
Beckerle, Mary C. | Cysteine-rich protein family of highly related LIM domain proteins | Here we describe a family of closely related LIM domain proteins in avian cells. The LIM motif defines a zinc-binding domain that is found in a variety of transcriptional regulators, proto-oncogene products, and proteins associated with sites of cell-substratum contact. One type of LIM-domain protei... | LIM domains; Chicken embryo fibroblasts; Quail embryo fibroblasts; Cell growth; Cell development; Cysteine-rich proteins | 1995 |
| 203 |
 |
Gesteland, Raymond F.; Krapcho, Karen J.; Talbot, Phil; Thulin, Craig | Crystallization of the MS2 translational repressor alone and complexed to bromouridine | The coat protein from the MS2 bacteriophage plays a dual role by encapsidating viral RNA and also by binding RNA as a translational repressor. In order to study the isolated dimer in a conformation not influenced by capsid interactions, a mutant molecule was crystallized that is defective in capsid ... | Crystallization; RNA Bacteriophage; RNA Hairpin; Translational Repressor | 1995 |
| 204 |
 |
Adler, Frederick R. | Stumped by trees? A generalized null model for patterns of organismal diversity | Evolutionary biologists increasingly have become interested in the factors determining the structure of phylogenetic trees. For example, highly asymmetric trees seem to suggest that the probability of extinction and/or speciation differs among lineages. | Evolutionary diversification; phylogenetic topologies; speciation | 1995 |
| 205 |
 |
Sperry, John S. | Hydraulic architecture of palms | The water transport and storage system of palms is adapted to maintain the primary stem xylem functional over the life of the shoot, and in spite of severe drought. However, our structural information far exceeds our knowledge of vascular function, and these functional considerations bring more que... | Hydraulic architecture; Rhapis excelsa; Cavitation | 1995 |
| 206 |
 |
Bohs, Lynn A. | Transfer of Cyphomandra (Solanaceae) and its species to Solanum | Data from recent molecular studies demonstrate that the genus Cyphomandra is nested within Solanum. Recognition of Cyphomandra as a separate genus therefore is not tenable unless Solanum is broken up into smaller monophyletic units. All Cyphomandra species are transferred to Solanum, necessitating t... | Cyphomandra; Solanum | 1995 |
| 207 |
 |
Capecchi, Mario R. | Genetic interaction between hoxb-5 and hoxb-6 is revealed by nonallelic noncomplementation. | hoxb-5 and hoxb-6 are adjacent genes in the mouse HoxB locus and are members of the homeotic transcription factor complex that governs establishment of the mammalian body plan. To determine the roles of these genes during development, we generated mice with a targeted disruption in each gene. Three ... | Alleles; CCAAT-Enhancer-Binding Proteins; Cervical Vertebrae; DNA-Binding Proteins; Forelimb; Genetic Complementation Test | 1995-01-01 |
| 208 |
 |
Capecchi, Mario R. | Introduction: the molecular genetic analysis of mouse development | This paper is an introduction of seven different papers presented in "Seminars in developmental biology" on Molecular Genetic Analysis of Mouse Development . The first paper, by Janet Rossant, describes very early mouse development. The second paper, by Frank Conlon and Rosa Beddington provide an i... | Embryo Culture Techniques; Genes | 1995-04 |
| 209 |
 |
Eichwald, Ernst; Capecchi, Mario R.; Thomas, Kirk R. | Mouse model for the delta F508 allele of cystic fibrosis | The most common cause of cystic fibrosis is a mutation that deletes phenylalanine 508 in cystic fibrosis transmembrane conductance regulator (CFTR). The delta F508 protein is misprocessed and degraded rather than traveling to the apical membrane. We used a novel strategy to introduce the delta F508 ... | Digestive System; Disease Models, Animal; Electrolytes; Mice, Inbred C57BL | 1995-10 |
| 210 |
 |
Olivera, Baldomero M.; Gray, William Robert | Contryphan is a D-tryptophan-containing Conus peptide | In this report, we document for the first time the occurrence of D-tryptophan in a normally translated polypeptide, contryphan. The peptide, isolated from the venom of the fish-hunting marine snail Conus radiatus, produces the "stiff-tail" syndrome in mice. | Conotoxins; Contryphan; D-tryptophan; Conus peptides; Conus radiatus; Stiff-tail syndrome | 1996 |
| 211 |
 |
Olivera, Baldomero M.; Ireland, Chris M. | NMR structures of conotoxins | This review discusses the methodology, structural details, and biological implications regarding NMR structures of conotoxins. NMR and molecular modeling techniques have improved to the point that three-dimensional structures of conotoxins can now be determined with a significant degree of confiden... | Conotoxins | 1996 |
| 212 |
 |
Clayton, Dale H. | Revision of the chewing louse genus Formicaphagus (Phthiraptera: Philopteridae) from Neotropical Antbirds and Gnateaters (Aves: Passeriformes) | Examination of specimens of the 15 recognized species of Formicaphagus resulted in 6 new synonymies: F. laemostictus, F. latifrons, and F. peruvianus are junior synonyms of F. picturatus; F. huilae of F. angustifrons; and F. bolivianus and F. thoracicus of F. minutus. Two new species are described f... | Formicaphagus; Formicaphagus arnoldi; Formicaphagus donpetersi; Antbirds; Gnateaters | 1996 |
| 213 |
 |
Davidson, Diane W. | Tropical arboreal ants: why so abundant? | ANTS ARE AMONG the most numerous and readily observed arthropods of tropical forests. Indeed, based on their standing biomass and many effects on other species, ants (Formicidae) are arguably the dominant arthropod family in the canopies of lowland rain forest trees (Tobin 1995). Others have tried t... | Arboreal ants; Tropics | 1996 |
| 214 |
 |
Ehleringer, James R. | Gas exchange, δ13C, and heterotrophy for Castilleja linariifolia and Orthocarpus tolmiei, facultative root hemiparasites on Artemisia tridentata | Gas exchange and carbon isotope ratios were measured on 2 facultative hemiparasites, Castilleja linarifolia Benth. (Indian paintbrush; Scrophulariaceae) and Orthocarpus tolmiei I-I. & A. (Tolmie owl clover; Scrophulariaceae), and their Artemisia tridentata L. (big sagebrush; Asteraceae) hosts. Photo... | Heterotrophy; Hemiparasite; Carbon isotope ratios; Shrub ecology; Castilleja linarifolia; Orthocarpus tolmiei; Artemisia tridentata | 1996 |
| 215 |
 |
Bastiani, Michael | Role of the cell surface in neuronal pathfinding | Perhaps the organ of the human body that evokes the most astonishment, and yet is the least understood, is our brain. From the coordination of simple movements, to consciousness and thought, the function of the nervous system relies on the establishment of trillions of precise connections among the... | Axon; molecular guidance code; growth cone | 1996 |
| 216 |
 |
Olivera, Baldomero M. | Identification and characterization of a Ca2+-sensitive nonspecific cation channel underlying prolonged repetitive firing in Aplysia neurons | The afterdischarge of Aplysia bag cell neurons has served as a model system for the study of phosphorylation-mediated changes in neuronal excitability. The nature of the depolarization generating the afterdischarge, however, has remained unclear. We now have found that venom from Conus textile trig... | Ca21-activated nonspecific cation channel; Slow inward current; Ion channel modulation; Afterdischarge; Bursting; Aplysia bag cell neurons; Conus textile; Neurotoxins | 1996 |
| 217 |
 |
Capecchi, Mario R. | Lessons from angiotensin-converting enzyme-deficient mice | Since the first description of renin by Tigerstedt and Bergman [1] in 1898, many papers have described the biochemistry and physiological roles of the reninangiotensin system [2]. A critical component of this system is angiotensin-converting enzyme (ACE), a peptidase which cleaves the inactive pep... | | 1996 |
| 218 |
 |
Bastiani, Michael | Developmental expression and biochemical analysis of Conulin, a protein secreted from a subset of neuronal growth cones | In this report, we analyze the developmental pattern of expression of a new grasshopper protein, Conulin, using the monoclonal antibody 7D2 on whole-mount embryos and dissociated neurons. We also have examined its biochemical properties by immunoblot analysis. Conulin is a protein expressed by a su... | Conulin; Growth cone-specific protein; Secreted protein; Selective tasciculation; CNS-specific protein; Pathfinding | 1996 |
| 219 |
 |
Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. Michael | New α-conotoxin which targets α3ß2 nicotinic acetylcholine receptors | We have isolated a 16-amino acid peptide from the venom of the marine snail Conus magus which potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3ß2 subunits. This peptide, named a-conotoxin MII, was identified by electrophysiologically screening venom fractions against cl... | Conotoxins; a-conotoxin MII; Conus magus | 1996 |
| 220 |
 |
Jorgensen, Erik | Genetic screens for synaptic function mutants in the nematode C. elegans | The synapse is the site of a remarkable conversion of electrical signals into chemical signals. This conversion takes place when a depolarizing impulse enters the axon terminal and opens voltage-sensitive calcium channels; calcium then flows into the cell and initiates the fusion of synaptic vesicle... | Vesicle; Neurotransmission; Cell | 1996 |
| 221 |
 |
Beckerle, Mary C. | Molecular characterization of human zyxin | Zyxin is a component of adhesion plaques that has been suggested to perform regulatory functions at these specialized regions of the plasma membrane. Here we describe the isolation and characterization of cDNAs encoding human and mouse zyxin. | Zyxin; Proline; LIM domains | 1996 |
| 222 |
 |
Davidson, Diane W.; Rickart, Eric Allan; Keiter, Robert B. | Selecting wilderness areas to conserve Utah's biological diversity | Congress is currently evaluating the wilderness status of Bureau of Land Management (BLM) public lands in Utah. Wilderness areas play many important roles, and one critical role is the conservation of biological diversity. | Bureau of Land Management; Conservation; Endemic species; Exotic species; Cryptobiotic soils; Plants; Bees; Vertebrates | 1996 |
| 223 |
 |
Ehleringer, James R. | Potential adaptability and constraints of response to changing climates for Encelia farinosa var. phenicodonta from southern Baja California, Mexico | To examine the physiological adaptability of Encelia farinosa var. phenicodonta from southern Baja California, plants from Todos Santos, BCS were raised in central Arizona where winter-spring precipitation is greater than typically experienced by this variety. Plants were capable of high photosynthe... | Encelia farinosa var. phenicodonta; Ecophysiology | 1996 |
| 224 |
 |
Beckerle, Mary C. | Two muscle-specific LIM proteins in Drosophila | The LIM domain defines a zinc-binding motif found in a growing number of eukaryotic proteins that regulate cell growth and differentiation during development. Members of the cysteine-rich protein (CRP) family of LIM proteins have been implicated in muscle differentiation in vertebrates. Here we r... | LIM domains; Mlp60A; Mlp84B; Cysteine-rich proteins | 1996 |
| 225 |
 |
Goller, Franz | Motor control of crystallized song is modified by sensory feedback | Song production requires precisely coordinated activity in the respiratory and syringcal (vocal organ) muscles. Crystallized adult song is characterized by acoustic and motor stereotypy which does not require auditory feedback, suggesting it is represented by fixed central motor programs. To determ... | Air injection; Auditory feedback; Pressure | 1997 |
