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Creator | Title | Description | Subject | Date |
176 |
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Frederick, Jeanne M. | Neurotransmitter properties of the newborn human retina. | Human retinal tissue from a newborn was examined autoradiographically for the presence of highaffinity uptake and localization of the following putative neurotransmitters: dopamine, glycine, GAB A, aspartate, and glutamate. In addition, the dopamine content of this newborn retina was measured by ... | Newborn; Human Retina; Neurotransmitter Properties; Photoreceptors | 1983 |
177 |
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Varner, Michael W. | Diagnosis of maternal cystic fibrosis during pregnancy. | The third and fourth cases of maternal cystic fibrosis diagnosed during pregnancy are presented. Quantitative pilocarpine iontophoresis (sweat chlorides) must be performed to establish the diagnosis. Other important findings include recurrent or persistent respiratory symptoms, chest x-ray abnormali... | Pregnancy; Cystic Fibrosis; Chlorides; Respiratory Insufficiency | 1983-03 |
178 |
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Varner, Michael W. | Endotoxin enhancement as a possible etiology of early-onset group B beta-hemolytic streptococcal sepsis in the newborn. | Group B streptococcal cells, either viable or heat-killed, contain a substance that induced fever in rabbits with maximal responses occurring four hours after intravenous injection. In contrast, supernatant fluids failed to induce significant fever. Group B streptococcal cells also enhanced host sus... | Newborns; Endotoxins; Group B Beta-Hemolytic Streptococcal Sepsis | 1983-05 |
179 |
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Capecchi, Mario R. | Location and function of retroviral and SV40 sequences that enhance biochemical transformation after microinjection of DNA. | Biochemical transformation of thymidine-kinase-deficient (TK-) mouse L cells is enhanced 20 to 40 fold when microinjected plasmid DNA contains regions of the genomes of Rous sarcoma virus or simian virus 40 in addition to the complete herpes simplex virus tk gene, irrespective of the orientation and... | Animals; Base Sequence; Genes, Viral; Plasmids; Thymidine Kinase | 1983-07-01 |
180 |
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Capecchi, Mario R. | Measurement of suppressor transfer RNA activity. | Transfer RNA (tRNA) suppression of nonsense mutations in prokaryotic systems has been widely used to study the structure and function of different prokaryotic genes. Through genetic engineering techniques, it is now possible to introduce suppressor (Su+) tRNA molecules into mammalian cells. A quanti... | Animals; Cells, Cultured; Eukaryotic Cells; Genes, Viral; Mice; Orthomyxoviridae; Peptide Chain Termination, Translational; Protein Biosynthesis | 1983-08-26 |
181 |
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Varner, Michael W. | Systemic lupus erythematosus. | Systemic lupus erythematosus is an autoimmune disease of unresolved cause afflicting predominantly women in their childbearing years. Speculation exists as to the relative roles of viruses, histocompatibility loci such as HLA-DR3, and estrogenmediated decreases in suppressor cell function. Whateve... | Systemic Lupus Erythematosus; Pregnancy Complications | 1983-09 |
182 |
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Warner, Homer R. | The HELP System | Biomedical Informatics | | 1984 |
183 |
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Warner, Homer R. | Decision-Driven Acquisition of Qualitative Data | Biomedical Informatics | | 1984 |
184 |
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Gardner, Reed M. | Measuring the Value of Information Systems | Biomedical Informatics | | 1984 |
185 |
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Gardner, Reed M. | Tomorrow's Electronic Hospital is Here Today | Biomedical Informatics | | 1984 |
186 |
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Gardner, Reed M. | Accuracy of Pulmonary Artery and Wedge Pressure Measurements (Letter) | Biomedical Informatics | | 1984 |
187 |
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Frederick, Jeanne M. | Inhibitors of metalloendoprotease activity prevent K+-stimulated neurotransmitter release from the retina of Xenopus laevis. | Metalloendoprotease activity was identified in retinal homogenates using a synthetic fluorogenic metalloendoprotease substrate and specific metalloendoprotease inhibitors. The requirement of metalloendoprotease activity in neurotransmitter release was examined during the depolarization-induced relea... | Neuromuscular Junction; Neurotransmitter Agents; Membrane Fusion | 1984 |
188 |
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Gardner, Reed M. | Frequency of Technical Problems Encountered in the Measurement of Pulmonary Artery Wedge Pressure | Biomedical Informatics | | 1984 |
189 |
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Gardner, Reed M. | Prospective Comparison of Arterial Catheter Blood and Catheter-Tip Cultures in Critically Ill Patients | Biomedical Informatics | | 1984 |
190 |
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Olson, Randall J.; Coldwell, Karin D.; Compton, Bruce J.; Giddings, John C. | Sedimentation field-flow fractionation: a method for studying particulates in cataractous lens | It is shown that the technique of sedimentation field-flow fractionation (sedimentation [sed] FFF) can be used to determine the particle content and particle size distribution of normal and cataractous lenses. A 31-year-old normal human lens, for example, showed a particle content of 1.5% by weight ... | Fractionation; Cataractous Lens; Particulates | 1984 |
191 |
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Varner, Michael W. | Decidual, amniotic fluid, maternal and fetal prolactin in normal and abnormal pregnancies. | In the present studies, the content and the in vitro production of prolactin by decidua as well as the concentrations of prolactin in amniotic fluid, maternal and fetal serum in normal term pregnancies, induced abortions at various gestational ages, and in pregnancies complicated by diabetes mellitu... | Decidual; Amniotic Fluid; Prolactin; Pregnancy Complications | 1984-03 |
192 |
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Varner, Michael W. | Multiple gestation: time interval between delivery of the first and second twins. | A clinical investigation was undertaken to challenge the commonly accepted view that the interval between the birth of the first and second twins should be preferably within 15 minutes and certainly no more than 30 minutes. During 1981 and 1982, 115 patients with live-born twins at 34 or more weeks'... | Twins; Time Interval Between Births; Fetal Monitoring | 1984-04 |
193 |
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Rogers, Alan R. | Sociobiology of sex and sexes (comment) | A comment on "Sociobiology of sex and sexes" by Marion Blute. | Sociobiology; Sex and sexes | 1984-04 |
194 |
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Varner, Michael W.; Digre, Kathleen B. | Pseudotumor cerebri and pregnancy. | Pseudotumor cerebri (PTC) is most commonly seen in obese women of reproductive age. We studied 109 women with PTC between ages 16 and 44 years. In 11, PTC started during pregnancy. Thirteen women with previous diagnosis of PTC, including two of the aforementioned 11, had an additional 17 documented ... | Pregnancy Complications; Pseudotumor Cerebri; Vision disorders; Headache; Intracranial Pressure | 1984-06 |
195 |
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Capecchi, Mario R. | Synthesis of an ochre suppressor tRNA gene and expression in mammalian cells. | We have used site-specific mutagenesis to change the anticodon of a Xenopus laevis tyrosine tRNA gene so that it would recognize ochre codons. This tRNA gene is expressed when amplified in monkey cells as part of a SV40 recombinant and efficiently suppresses termination at both the ochre codon separ... | Xenopus; Nucleic Acid Conformation; Kidney; DNA Restriction Enzymes | 1984-11 |
196 |
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Warner, Homer R. | HELP - A Medical Information System Which Combines Automated Medical Decision-Making With Clinical Data Review and Administrative Support | Biomedical Informatics | | 1985 |
197 |
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Warner, Homer R. | HELP: A Medical Information System With Decision Making Capability | Biomedical Informatics | | 1985 |
198 |
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Warner, Homer R. | HELP/PATHLAB Integration - A Decade of Experience Using an Expert System Interfaces to a Clinical Laboratory System | Biomedical Informatics | | 1985 |
199 |
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Warner, Homer R. | Development of a Computerized Infectious Disease Monitor (CIDM) | Biomedical Informatics | | 1985 |
200 |
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Warner, Homer R. | The Library and the Department of Medical Informatics: Collaboration or Conflict | Biomedical Informatics | | 1985 |