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TitleDescriptionSubject
126 Pendular, gaze-evoked and abducting nystagmus in MSThis is a 40-year-old woman with a history of multiple sclerosis who presented for oscillopsia. On examination, she had bilateral internuclear ophthalmoplegia (INO-adduction lag OU and abducting nystagmus OU), with a corresponding exotropia that increased in right and left gaze. She also had horiz...Jerk Nystagmus, INO, Pendular Nystagmus; Abducting Nystagmus, Gaze-Evoked Nystagmus, Cerebellar OMS
127 Periodic Alternating Nystagmus due to Spinocerebellar Ataxia Type 6This 50-yo-man complained of imbalance for several years and more recently oscillopsia. On examination, there was saccadic pursuit and VOR suppression in addition to gaze-evoked nystagmus with rebound, raising suspicion for a vestibulocerebellar localization. Additionally, there was periodic alterna...Cerebellar; Jerk nystagmus; Periodic alternating nystagmus; Gaze evoked nystagmus; Rebound nystagmus
128 Periodic alternating nystagmus and perverted head-shaking nystagmus in cerebellar degenerationThis is a 60-yo-woman with several years of worsening imbalance, diplopia (hers was actually unrelated to cerebellar pathology [although she did have an esotropia greater at distance that was cerebellar in origin] and due to thyroid eye disease) and blurry vision (due to her spontaneous nystagmus). ...Headshaking, Cerebellar, Jerk Nystagmus, Periodic Alternating Nystagmus
129 Periodic alternating nystagmus due to nodulus strokeThis is a 70-year-old woman who experienced the acute onset of vertigo and imbalance. MRI demonstrated a diffusion-weighted imaging hyperintensity involving the nodulus (with corresponding ADC hypointensity) consistent with an acute stroke. On examination several weeks after the stroke, periodic alt...Periodic Alternating Nystagmus, Jerk Nystagmus
130 Periodic alternating nystagmus due to nodulus stroke - Figure 1This is a 70-year-old woman who experienced the acute onset of vertigo and imbalance. MRI demonstrated a diffusion-weighted imaging hyperintensity involving the nodulus (with corresponding ADC hypointensity) consistent with an acute stroke. On examination several weeks after the stroke, periodic alt...Periodic Alternating Nystagmus, Jerk Nystagmus
131 Peripheral (vestibular) and central (gaze-evoked) patterns of nystagmus in a single patientA 55-year-old man experienced episodic vertigo and was diagnosed with Meniere's disease affecting the left ear (based on audiograms and his clinical course) about 1 year prior to presentation. About 6 months prior to presentation, intratympanic (IT) gentamicin was injected into the left ear, at whic...Jerk Nystagmus, Vestibular Nystagmus, Bruns, Gaze Evoked Nystagmus, VOR HIT Abnormal
132 Pons: 6th and 7th nerve anatomy and the central tegmental tractFrom this cross-section of the pons, the proximity of the 6th nucleus to the 7th nerve fascicles is apparent. This is the basis of the so-called facial colliculus syndrome, where an ipsilesional horizontal gaze palsy from a nuclear 6th lesion (usually related to stroke or demyelination) can be seen ...Sixth Nerve Palsy, INO, One and a Half, Horizontal Gaze Palsy, OMS Pons, Facial Nerve, Oculopalatal
133 Pons: 6th, 7th, 8th, and middle cerebellar peduncle anatomyFrom this cross-section of the pons, the proximity of the 7th and 8th fascicles can be appreciated, and a lateral inferior pontine syndrome (anterior inferior cerebellar artery territory), which could involve both of these fascicles, could cause acute prolonged vertigo accompanied by a + ipsilateral...Sixth Nerve Palsy, OMS Pons, Facial Nerve, VOR Normal, VOR Abnormal
134 Pontine hemorrhage causing oculopalatal tremor and multiple cranial neuropathiesThis is a 45-yo-woman who had a dorsal pontine cavernoma that bled 2 years prior to this video. Symptoms included diplopia and oscillopsia. On examination, she had left>right facial palsies (upper and lower face from involvement of the nucleus/fascicle - i.e., lower motor neuron palsies) and sixth n...Sixth Nerve Palsy; Pons; Pendular Nystagmus; Oculopalatal Tremor
135 Positional downbeat nystagmus mimicking anterior canal BPPVAlthough positional downbeat nystagmus (pDBN) can indicate the rare anterior canal variant of benign paroxysmal positional vertigo, central mimics are common causes of pDBN. pDBN may be seen in multiple system atrophy (MSA), or seen with posterior fossa lesions, with a common example being a stroke ...Cerebellar, Jerk Nystagmus, Downbeat Nystagmus, Central Positional Nystagmus
136 Post-infectious ocular flutter and myoclonus syndromeThis is a 35-yo-woman presenting with oscillopsia following a viral illness. She described being easily startled, with "shakiness" of the head/neck and body. She had myoclonus and ocular flutter, with the latter evident when she initiated saccades. Eye movement recordings showed that most of her sac...Flutter
137 Posterior Canal - BPPV: Epley and Semont maneuversEpley/canalith repositioning maneuver (CRP) To treat right posterior canal (PC)-BPPV (each position maintained for at least 30 seconds or until nystagmus and/or vertigo cease): • First the patient is placed in the long-sitting position • The head is rotated 45 degrees to the right • Then the p...Benign Paroxysmal Positional Vertigo; BPPV; Posterior Canal; Epley Canalith Repositioning Maneuver - CRP; Semont Maneuver; Exam; Examination
138 Posterior canal BPPV pre- and post-Epley maneuverThis is a patient with typical right posterior canal benign paroxysmal positional vertigo (BPPV), which was provoked by the Dix-Hallpike maneuver. When the patient was moved into the right Dix-Hallpike maneuver, after a brief latency, upbeat-torsional (towards the lowermost or affected [right] ear) ...BPPV Posterior, BPPV Diagnosis, BPPV Treatment, Jerk Nystagmus, Vestibular Nystagmus,
139 Posterior canal BPPV treated with Semont maneuverThis is a patient with left posterior canal (PC) benign paroxysmal positional vertigo (BPPV), and upbeat-torsional (towards the left ear) nystagmus was provoked by left Dix-Hallpike maneuver and left side-lying maneuver. This video demonstrates treatment of her left PC BPPV with the Semont maneuver....BPPV Posterior, BPPV Diagnosis, BPPV Treatment, Jerk Nystagmus, Vestibular Nystagmus
140 Posterior canal BPPV with fixation and with fixation removedThis is a 60-yo-woman with positional vertigo. In the right Dix-Hallpike position with fixation removed, there was clear upbeat-torsional nystagmus (towards the lowermost right ear) which led to the diagnosis of right posterior canal BPPV. In right Dix-Hallpike with fixation there was mainly torsion...Benign Paroxysmal Positional Vertigo; BPPV, Dix-Hallpike, posterior canal; Vestibular nystagmus; Jerk nystagmus
141 Pressure testing for superior canal dehiscence syndromeSuperior semicircular canal dehiscence syndrome (SCDS) is caused by a third mobile window in the inner ear. This allows for transmission of sound or pressure to the superior canal. Tragal compression and/or glottic and pinched nose Valsalva may provoke vertigo and vertical-torsional nystagmus in t...Valsalva; Superior canal dehiscence syndrome
142 Prolonged lid twitch in myasthenia gravisThis 50-yo-woman with ocular MG demonstrated a spontaneous and particularly prolonged eyelid twitch.Myasthenia Gravis
143 Provocative maneuvers (removal of fixation, vibration, head-shaking) to accentuate peripheral vestibular nystagmus)With an acute destructive process like vestibular neuritis that causes significant unilateral vestibular loss, spontaneous nystagmus is always present. However, over days to months, spontaneous nystagmus should resolve completely. In a patient with vestibular neuritis involving the right side, left-...Headshaking Nystagmus
144 Pseudo-INOs in myasthenia gravisThis is a 55-yo-woman with an intermittent exotropia who had normal adduction OU, but clear lag of adducting saccades OD>OS with rapid horizontal saccades. This was much more apparent after repeat testing (ie, it was fatigable), and she wound up having ocular MG.Myasthenia Gravis, INO, Abnormal Saccades
145 Pseudo-spontaneous nystagmus and bow and lean test in horizontal canal BPPVThis is a 70-year-old woman presenting to the Emergency Department with positional vertigo that was determined to be due to the apogeotropic variant of right horizontal canal (HC) benign paroxysmal positional vertigo (BPPV). When her head is in a neutral position with the head in axis with the trunk...Benign Paroxysmal Positional Vertigo; BPPV; Horizontal Canal; Jerk nystagmus; Vestibular nystagmus; Head shaking
146 Range of Eye Movements and Evaluation for NystagmusRange: Assesses for motility deficit due to an ocular motor palsy, particularly if a posterior fossa localization is being considered; Nystagmus: Spontaneous nystagmus may or may not be noted and gaze-evoked nystagmus is common with posterior fossa lesions; nystagmus that is unidirectional in all di...Exam, Nystagmus, Range of Eye Movements
147 Rebound nystagmusThis is a 50-yo-man who presented for dizziness and imbalance. His exam demonstrated choppy smooth pursuit and VOR suppression as well as mild gait ataxia. There was mild right-beating nystagmus in right gaze and left-beating nystagmus in left gaze without vertical gaze-evoked nystagmus. Occasionall...Cerebellar, Jerk Nystagmus, Gaze Evoked Nystagmus, Rebound Nystagmus
148 Relationship between semicircular canals and extraocular musclesFigure 1: When stimulated, each of the 6 angular acceleration detecting semicircular canals (3 on the right and 3 on the left) responds with a conjugate eye movement, with the vector(s) indicated below. PC=posterior canal; HC=horizontal (also known as lateral) canal; AC=anterior (also known as super...Extraocular Muscles
149 Reversal of vertical nystagmus with convergence in anti-DPPX encephalitisThis is a man who initially presented with spontaneous upbeat and torsional nystagmus, which led to the diagnosis of anti-DPPX encephalitis (for further details on this patient's course and for a video of his nystagmus, see reference 1). Over 6-12 months, his spontaneous (mainly) upbeat nystagmus (U...Upbeat Nystagmus; Downbeat Nystagmus; Jerk Nystagmus; Gaze-Evoked Nystagmus
150 Rotary Chair TestingRotary chair testing includes rotation around a vertical axis, and evaluates the horizontal semicircular canal vestibulo-ocular reflex (VOR). The patient sits in a mechanized chair with the head secured in a neutral position or in 30 degree forward flexion (to better isolate the horizontal canals)....Normal VOR, Abnormal VOR, Vestibular Lab Testing, Rotary Chair
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