Honors Theses Open Access
 
Filters: School Or College: "College of Science" Collection: "ir_htoa"
126 - 150 of 183
Number of results to display per page
CreatorTitleDescriptionSubjectDate
126 Trakhimets, AlesiaPre-clinical trials of anti-neoplastic drugs using zebrafish with T-cell cancerNote: To agree with NCBI nomenclature guidelines, human gene abbreviations are italicized and capitalized; human protein abbreviations are non-italicized and capitalized, and zebrafish gene abbreviations are italicized in lowercase. T lymphocytes, or T-cells, are blood cells that normally fight vira...Antineoplastic agents - Testing; Zebra danio2013-04
127 Christensen, KianaQuantifying Patterns of Squamate Dental ComplexitySquamate reptiles are ideal subjects for investigating relationships between diet and dentition patterns because they exhibit wide dietary diversity and taxonomic abundance. Most previous research is qualitative and limited to a basic assessment of the influence diet has on dentition (Hotton, 1955; ...2020
128 Tuft, MarieQuantitative analysis of virus trafficking in a biological cellVirus replication is a complex process that is important to understand. If a virus is to successfully infect a host cell it must travel from the cell wall to the nucleus by hijacking that cell's existing transport system of microtubules. This motion occurs as two iterated steps: passive diffusion th...Viruses -- Reproduction -- Mathematical models; Virus trafficking2015-05
129 Dutson, Matthew J.Reconstruction of Cosmic Ray Geometry using Cherenkov backscatteringFluorescence detectors are often used to examine the energy spectrum and arrival directions of ultra high energy cosmic rays. An accurate reconstruction of geometry is key when determining both energy and direction. In the past, it has been necessary to build multiple fluorescence detectors to take ...2017
130 Bingham, KouverReflection groups and coxeter groupsIn this paper we give a survey of the theory of Coxeter Groups and Reflection groups. This survey will give an undergraduate reader a full picture of Coxeter Group theory, and will lean slightly heavily on the side of showing examples, although the course of discussion will be based on theory. We'll...Finite groups2014-07
131 Ellis, James H.Refractory status epilepticus and chronic kidney disease in a large pedigree due to a variant in the mitochondrial encoded trna phenylalanine (MT-TF) geneMitochondrial disorders present with a wide spectrum of neurological manifestations. Clinical syndromes are described largely by phenotypic indicators. Epilepsy is a common but not universal feature. Myoclonus epilepsy with ragged red fibers (MERRF) is a common clinical syndrome that presents with e...2018
132 Steiner, WilliamRegulation of protein complexes during hedgehog signal transductionThe Hedgehog (Hh) pathway is an evolutionarily conserved signaling pathway essential in embryonic development and tissue homeostasis. Several cancers can form as a result of Hh pathway dysfunction. The G protein-coupled receptor (GPCR) Smoothened (SMO) is activated upon binding of the secreted Hh pr...2021
133 Wheeler, MayaRole of WNT-Dependent Neurogenesis in Functional Recovery Following Spinal Cord InjuryIn humans and other adult mammals, spinal cord injury leads to a permanent loss of motor and sensory function. The biggest obstacle to recovery is the inability of severed axons and neurons to regenerate. During embryogenesis, all vertebrates have a population of neural stem cells called radial glia...2019
134 Nguyen, NamRoles of Transient Receptor Potenitial Ankyrin-1 and Vanilloid-3 in Endoplasmic Reticulum stress and Cytotoxicity in Lung Epithelial CellsAir pollution is a growing global health issue with considerable local relevance. In particular, exposure to wood smoke particulate matter (WSPM) is associated with the development and exacerbation of chronic inflammatory conditions and irreversible damage of the airways and alveoli. However, exact ...2020
135 Christopherson, AnnaSearch for the highest energy gamma rays of galactic origin using telescope array low energy fluorescence detectorsTelescope Array (TA) is the largest cosmic ray detector in the Northern Hemisphere, designed to measure cosmic rays with energies greater than 1018 eV. TA combines three fluorescence telescope sites, which are each instrumented with 12-14 telescopes, surrounding an array of 507 surface detectors tha...2022
136 Gregersen, DylanSearching for extragalactic stars among candidate halo moving clustersWe seek to identify stars accreted into the Milky Way which are remnants of its merging with smaller galaxies or star clusters. In our approach, we selected stars from candidate moving clusters in the Milky Way's Halo. These stars were grouped by similar stellar characteristics: orbital energy, orbi...Halo stars; Extragalactic origins; Milky Way2012-05
137 Duffin, CalderSequence Activity Relaqtionships in a Radical Sam Peptide MaturaseRibosomally synthesized and post-translationally modified peptide Tte1186a and several point mutation variants are synthesized using solid phase peptide synthesis with FMOC amino acids. Substrate recognition and thioether linkage formation from the radical S-adenosyl methionine Tte1186 maturase is d...2020
138 Hunter, SamuelSignaling Role of the Hamp Domain in the Escherichia Coli Serine ChemoreceptorThe chemoreceptor Tsr enables Escherichia coli to track serine gradients in its environment. Binding of serine to the periplasmic domain propagates a signaling conformational change through other domains of the chemoreceptor molecule to modulate the activity of CheA, a kinase associated with t...Chemoreceptors - Research2016-07
139 Olsen, NicholasSimple Molecular Models for Chiral CrystallizationChiral molecules play an important role in many biological processes.1 Important chiral biomolecules include certain amino acids, sugars, DNA, RNA, and many proteins. Chiral molecules have enantiomers, mirror-image isomers that cannot be superimposed on each other. The classic analogy to enantiomers...2020
140 Blair, Coral DeanSnakes as a possible winter reservoir for Western equine encephalitis virusviruses; equine; snakes1964
141 Jensen, Trey W.Spectral evolution in high redshift quasars from the final boss sampleWe report on a study of the spectral variations in a sample of 102,150 quasars from the Baryon Oscillation Spectroscopic Survey (BOSS) of the Sloan Digital Sky Survey (SDSS-III). After mitigating selection effects and Malmquist bias over the redshift range 2:1 □ z □ 3:5, we create high...Quasars -- Spectra; Red shift -- Observations; Baryon Oscillation Spectroscopic Survey; Sloan Digital Sky Survey; Redshift evolution
142 Auduong, PriscillaSpinal muscular atrophy modeled in drosophila melanogasterSpinal Muscular Atrophy (SMA) is the most commonly inherited cause of death in children (Park, Kariya, & Monani, 2010 for review). This disease is characterized by a loss of motor neurons which leads to muscle degeneration, paralysis, and eventual death by respiratory failure (Monani, 2005 for revie...Spinal muscular atrophy - Research; Drosophila melanogaster - Researcher2012-05
143 Thompson, LaurenSptlC2 Deletion in Endothelial Cells: Implications for Arterial FunctionUsing pharmacological and genetic approaches to inhibit whole-body ceramide biosynthesis, our laboratory showed that this sphingolipid contributes importantly to hypertension and vascular dysfunction associated with diet-induced obesity in mice. Here we tested the hypothesis that inducible, endothel...2020
144 Hahm, SuhyunStressors of varying properties induce differences in the modulation of behavior and biologyStress induces enduring behavioral and biological consequences. Despite its pervasiveness, the biological and neural processes underlying its effects remain largely unknown. The existing literature generally examines the repercussions of stress from the aspect of a single stressor; however, stressor...2022
145 Skedros, Gregory AthanasiosStructural and material changes in the sheep radius from newborn to adult: Functional adaptation versus developmental constraintBones that exhibit marked changes in structural and material characteristics during ontogeny are potentially useful for studying the mechanisms that produce functional adaptations. The diaphyseal region of the sheep radius was examined because it is relatively simply loaded in cranial-caudal bending...Functional adaptations - Sheep; Developmental constraint - Sheep; Ontogeny2015-08
146 Farrall, NicholasStructural characterization of the full-length exocyst complex by transmission electron cryo-microscopyThe exocyst is a conserved octameric protein complex in eukaryotes that is essential for tethering and fusion of vesicles to the plasma membrane. Composed of eight subunits, it is essential for growth, secretion, and developmental processes and has been implicated in cell motility, autophagy, cell d...Saccaromyces cerevisaie - Cytology; Cryomiscroscopy - Research2014-05
147 Dyer, JamieStudies of Spectral Variability of Quasars with Multi-Epoch AnalysesQuasars are supermassive black holes known to drive galaxy formation. They can have masses up to 109 solar masses and are the most luminous known objects in the sky, making them very important trackers of cosmic evolution. Given the large amount of research already surrounding quasar astrophysics, t...2017
148 Bull, August JohnStudying Galois Representations Using Elliptic CurvesDiophantine equations and their solution sets are prominent subjects of study in number theory. These equations are often studied modulo prime numbers or prime ideals in field extensions. Galois Theory is well-suited to study field extensions, but Galois groups are often mysterious. To remedy this, ...2020
149 Watkins, Ryan DavisSuppression of lymphangiogenesis using VEGF-C trapThe lymphatic system is responsible for controlling systemic fluid buildup. Lymphangiogenesis is a dynamic process involving sprouting, and maintaining new lymphatic vasculature. Vascular endothelial growth factor C (VEGF-C) is as a key growth factor that induces lymphangiogenesis by binding VEGF re...Lymphatics - Growth; Vascular endothelial growth factors - Antagonists; Lymphangiogenesis; VEGF-C trap2014-05
150 Reece, Eric J.Synthesis and Characterization of Proton Conducting Silica Nano-Particles for use in Polymer Electrolyte Membrane Fuel CellsOne of the fastest growing fields in scientific research is alternative energy. This has led to an investigation into the various aspects of fuel cells and their components due to their highly efficient energy conversion and low CO2 emissions. The efficiency of fuel cells is highly dependent on the ...2019
126 - 150 of 183