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101 Gerig, Guido4D active cut: an interactive tool for pathological anatomy modeling4D pathological anatomy modeling is key to understanding complex pathological brain images. It is a challenging problem due to the difficulties in detecting multiple appearing and disappearing lesions across time points and estimating dynamic changes and deformations between them. We propose a novel...2014-01-01
102 Gerig, Guido4D modeling of infant brain growth in Down's Syndrome and controls from longitudinal MRIModeling of early brain growth trajectories from longitudinal MRI will provide new insight into neurodevelopmental characteristics, timing and type of changes in neurological disorders from controls. In addition to an ongoing large-scale infant autism neuroimaging study 1, we recruited 4 infants wit...2014-01-01
103 Gerig, GuidoMulti-atlas segmentation of subcortical brain structures via the AutoSeg software pipelineAutomated segmenting and labeling of individual brain anatomical regions, in MRI are challenging, due to the issue of individual structural variability. Although atlas-based segmentation has show its potential for both tissue and structure segmentation, due to the inherent natural variability as wel...2014-01-01
104 Planelles, VicenteAn HIV-encoded antisense long non-coding RNA epigenetically regulates viral transcriptionThe abundance of long non-coding RNAs (lncRNAs) and their wide range of functional roles in human cells are fast becoming realized. Importantly, lncRNAs have been identified as epigenetic modulators and consequently play a pivotal role in the regulation of gene expression. A human immunodeficiency v...2014-01-01
105 Awate, Suyash PrakashMultiatlas segmentation as nonparametric regressionThis paper proposes a novel theoretical framework to model and analyze the statistical characteristics of a wide range of segmentation methods that incorporate a database of label maps or atlases; such methods are termed as label fusion or multiatlas segmentation.We model these multiatlas segmentati...2014-01-01
106 Gerig, GuidoParametric regression scheme for distributions: analysis of DTI fiber tract diffusion changes in early Brain DevelopmentTemporal modeling frameworks often operate on scalar variables by summarizing data at initial stages as statistical summaries of the underlying distributions. For instance, DTI analysis often employs summary statistics, like mean, for regions of interest and properties along fiber tracts for populat...2014-01-01
107 Seyedhosseini Tarzjani, Seyed MojtabaA workflow for the automatic segmentation of organelles in electron microscopy image stacksElectron microscopy(EM) facilitates analysis of the form,distribution, and functional status of key organelle systems in various pathological processes,including those associated with neurodegenerative disease.Such EM data often provide important new in sights into the underlying disease mechanisms....2014-01-01
108 Gerig, GuidoNormative modeling of early brain maturation from longitudinal DTI reveals twin-singleton differencesEarly brain development of white matter is characterized by rapid organization and structuring. Magnetic Resonance diffusion tensor imaging (MR-DTI) provides the possibility of capturing these changes non-invasively by following individuals longitudinally in order to better understand departures fro...2014-01-01
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