51 - 75 of 114
Number of results to display per page
51 Taylor, MarkUnderstanding the community based participatory research (CBPR) approach: case study in GhanaIn 2003, the University of Utah, in cooperation with Kwame Nkrumah University of Science and Technology (KNUST), Komfo Anokye Teaching Hospital (KATH), the Atwima Nwabiagya District Assembly and Barekuma community leaders, formed what is known as the Barekuma Collaborative Community Development Proj...2011-12-01
52 Gerig, GuidoBuilding spatiotemporal anatomical models using joint 4-D segmentation, registration, and subject-specific atlas estimationLongitudinal analysis of anatomical changes is a vital component in many personalized-medicine applications for predicting disease onset, determining growth/atrophy patterns, evaluating disease progression, and monitoring recovery. Estimating anatomical changes in longitudinal studies, especially th...2012-01-01
53 Gerig, GuidoLongitudinal growth modeling of discrete-time functions with application to DTI tract evolution in early neurodevelopmentWe present a new framework for spatiotemporal analysis of parameterized functions attributed by properties of 4D longitudinal image data. Our driving application is the measurement of temporal change in white matter diffusivity of fiber tracts. A smooth temporal modeling of change from a discrete-ti...2012-01-01
54 Gerig, GuidoA framework for longitudinal data analysis via shape regressionTraditional longitudinal analysis begins by extracting desired clinical measurements, such as volume or head circumference, from discrete imaging data. Typically, the continuous evolution of a scalar measurement is estimated by choosing a 1D regression model, such as kernel regression or fitting a p...2012-01-01
55 Gerig, GuidoPatient-tailored connectomics visualization for the assessment of white matter atrophy in traumatic brain injuryAvailable approaches to the investigation of traumatic brain injury (TBI) are frequently hampered, to some extent, by the unsatisfactory abilities of existing methodologies to efficiently define and represent affected structural connectivity and functional mechanisms underlying TI-related pathology....2012-01-01
56 Gerig, GuidoMeasures for validation of DTI tractographyThe evaluation of analysis methods for diffusion tensor imaging (DTI) remains challenging due to the lack of gold standards and validation frameworks. Significant work remains in developing metrics for comparing fiber bundles generated from streamline tractography. We propose a set of volumetric and...2012-01-01
57 Gerig, GuidoStatistical growth modeling of longitudinal DT-MRI for regional characterization of early brain developmentA population growth model that represents the growth trajectories of individual subjects is critical to study and understand neurodevelopment. This paper presents a framework for jointly estimating and modeling individual and population growth trajectories, and determining significant regional diffe...2012-01-01
58 Gerig, GuidoQuantifying regional growth patterns through longitudinal analysis of distances between multimodal MR intensity distributionsQuantitative analysis of early brain development through imaging is critical for identifying pathological development, which may in turn affect treatment procedures. We propose a framework for analyzing spatiotemporal patterns of brain maturation by quantifying intensity changes in longitudinal MR i...2012-01-01
59 Wunderlich, Adam JamesOn efficient assessment of image-quality metrics based on linear model observersThis paper is motivated by the problem of image-quality assessment using model observers for the purpose of development and optimization of medical imaging systems. Specifically, we present a study regarding the estimation of the receiver operating characteristic (ROC) curve for the observer and ass...2012-01-01
60 Gerig, GuidoAutomatic corpus callosum segmentation using a deformable active Fourier contour modelThe corpus callosum (CC) is a structure of interest in many neuroimaging studies of neuro-developmental pathology such as autism. It plays an integral role in relaying sensory, motor and cognitive information from homologous regions in both hemispheres. We have developed a framework that allows auto...2012-01-01
61 Gerig, GuidoSegmentation of serial MRI of TBI patients using personalized atlas construction and topological change estimationTraumatic brain injury (TBI) due to falls, car accidents, and warfare affects millions of people annually. Determining personalized therapy and assessment of treatment efficacy can substantially benefit from longitudinal (4D) magnetic resonance imaging (MRI). In this paper, we propose a method for s...2012-01-01
62 Gerig, Guido3D tensor normalization for improved accuracy in DTI tensor registration methodsThis paper presents a method for normalization of diffusion tensor images (DTI) to a xed DTI template, a pre-processing step to improve the performance of full tensor based registration methods. The proposed method maps the individual tensors of the subject image in to the template space based on ma...2012-01-01
63 Gerig, GuidoTopology preserving atlas construction from shape data without correspondence using sparse parametersStatistical analysis of shapes, performed by constructing an atlas composed of an average model of shapes within a population and associated deformation maps, is a fundamental aspect of medical imaging studies. Usual methods for constructing a shape atlas require point correspondences across subject...2012-01-01
64 Gerig, GuidoAnalysis of longitudinal shape variability via subject specific growth modelingStatistical analysis of longitudinal imaging data is crucial for understanding normal anatomical development as well as disease progression. This fundamental task is challenging due to the difficulty in modeling longitudinal changes, such as growth, and comparing changes across different populations...2012-01-01
65 Gerig, GuidoMixed-effects shape models for estimating longitudinal changes in anatomy2012-01-01
66 Macleod, Robert S.Identification and acute targeting of gaps in atrial ablation lesion sets using a real-time magnetic resonance imaging systemBackground-Radiofrequency ablation is routinely used to treat cardiac arrhythmias, but gaps remain in ablation lesion sets because there is no direct visualization of ablation-related changes. In this study, we acutely identify and target gaps using a real-time magnetic resonance imaging (RT-MRI) sy...2012-01-01
67 Pascucci, ValerioExploring performance data with boxfishThe growth in size and complexity of scaling applications and the systems on which they run pose challenges in analyzing and improving their overall performance. With metrics coming from thousands or millions of processes, visualization techniques are necessary to make sense of the increasing amount...2012-01-01
68 Wunderlich, Adam JamesA nonparametric procedure for comparing the areas under correlated LROC curvesIn contrast to the receiver operating characteristic (ROC) assessment paradigm, localization ROC (LROC) analysis provides a means to jointly assess the accuracy of localization and detection in an observer study. In a typical multireader, multicase (MRMC) evaluation, the data sets are paired so that...2012-01-01
69 Gerig, GuidoModeling longitudinal MRI changes in populations using a localized, information-theoretic measure of contrastLongitudinal MR imaging during early brain development provides important information about growth patterns and the development of neurological disorders. We propose a new framework for studying brain growth patterns within and across populations based on MRI contrast changes, measured at each time ...2013-01-01
70 Gerig, GuidoSpatiotemporal modeling of distribution-valued data applied to DTI tract evolution in infant neurodevelopmentThis paper proposes a novel method that extends spatiotemporal growth modeling to distribution-valued data. The method relaxes assumptions on the underlying noise models by considering the data to be represented by the complete probability distributions rather than a representative, single-valued su...2013-01-01
71 Gerig, GuidoAnalyzing imaging biomarkers for traumatic brain injury using 4D modeling of longitudinal MRIQuantitative imaging biomarkers are important for assessment of impact, recovery and treatment efficacy in patients with traumatic brain injury (TBI). To our knowledge, the identification of such biomarkers characterizing disease progress and recovery has been insufficiently explored in TBI due to d...2013-01-01
72 Gerig, GuidoAnalysis of diffusion tensor imaging for subjects with Down SyndromeAuthors: Neda Sadeghi1, Clement Vachet1, Marcel Prastawa1, Julie Korenberg1, Guido Gerig1 Institutions: 1University of Utah, Salt Lake City, UT Introduction: Down syndrome (DS) is the most common chromosome abnormality in humans. It is typically associated with delayed cognitive development and phys...2013-01-01
73 Gerig, GuidoA longitudinal structural MRI study of change in regional contrast in Autism Spectrum DisorderAuthors: Avantika Vardhan1, Joseph Piven2, Marcel Prastawa3, Guido Gerig3 Institutions: 1Scientific Computing and Imaging Institute, University of Utah, Salt Lake City, United States, 2Dept of Psychiatry, UNC School of Medicine, Chapel Hill, NC, 3University of Utah, Salt Lake City, UT Introduction: ...2013-01-01
74 Gerig, GuidoGeodesic image regression with a sparse parameterization of diffeomorphismsImage regression allows for time-discrete imaging data to be modeled continuously, and is a crucial tool for conducting statistical analysis on longitudinal images. Geodesic models are particularly well suited for statistical analysis, as image evolution is fully characterized by a baseline image an...2013-01-01
75 Gerig, GuidoMultivariate Modeling of longitudinal MRI in early brain development with confidence measuresThe human brain undergoes rapid organization and structuring early in life. Longitudinal imaging enables the study of these changes over a developmental period within individuals through estimation of population growth trajectory and its variability. In this paper, we focus on maturation of white an...2013-01-01
51 - 75 of 114