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CreatorTitleDescriptionSubjectDate
51 Couldwell, William T.Experience with use of extended length peritoneal shunt cathetersThe placement of a ventriculoperitoneal (VP) shunt is the current treatment of choice for diversion of cerebrospinal fluid associated with hydrocephalus. Although there are a host of reported potential abdominal complications related to the procedure, they are notably uncommon. The authors report t...1996
52 Couldwell, William T.Petroclival meningiomas: surgical experience in 109 casesThe surgical removal of petroclival meningiomas has historically been associated with a high incidence of morbidity and mortality. The 109 consecutive patients included in the present retrospective study represent a combined series of tumors operated on by the four authors during a period from 1980 ...Petroclival meningiomas; Clivus; Brain neoplasm; Petrous bone; Posterior fossa; Skull base tumor1996
53 Schmidt, Meic H.Role of light-emitting diodes for photodynamic therapy of brain tumorsThe development of more effective light sources for Photodynamic Therapy (PDT) of brain tumors would be of benefit for both research and clinical application. In this study, the use of light-emitting diode arrays for PDT of brain tumors with Photofrin® porfimer sodium was investigated. An inflatabl...Aluminum Gallium Arsenide; Photodynamic therapy; Brain tumors; Photofrin1996
54 Kestle, John R. W.Significance of bacteriologically positive ventriculoperitoneal shunt components in the absence of other signs of shunt infectionThe purpose of this study was to determine the significance of "asymptomatic bacteriological shunt contamination" (ABSC), defined as a positive bacteriological culture found on a ventricular shunt component in the absence of bacteria in the cerebrospinal fluid (CSF) culture and/or clinical evidence ...Ventricular shunt; Shunt infection; Ventriculoperitoneal shunt; Asymptomatic bacteriological; Shunt contamination1996
55 Couldwell, William T.Inhibition of cellular growth and induction of apoptosis in pituitary adenoma cell lines by the protein kinase C inhibitor hypericin: potential therapeutic applicationProtein kinase C (PKC) is an enzyme involved in the regulation of cellular growth, proliferation, and differentiation in a number of tissues including the anterior pituitary, in which it is also believed to play a role in hormone secretion. Protein kinase C activity and expression have been found to...Apoptosis; Hypericin; Pituitary adenoma; Protein kinase C1996
56 Kestle, John R. W.Does thalamotomy alter the course of Parkinson's disease?Irving Cooper (3) observed that unilateral Parkinson's disease seemed less likely to progress to the other side of the body after thalamotomy that abolished contralateral tremor and rigidity, an effect that he felt might be the result of either the surgery itself or the slow progression of that par...1996
57 Kestle, John R. W.Determining the best cerebrospinal fluid shunt valve design: the pediatric valve design trialMyriad cerebrospinal fluid shunt valve designs are available (17, IS). None has ever been shown to be superior to another, although claims by neurosurgeons and shunt manufacturers of the merits of particular designs are numerous. Such is the case with two recent shunt valve designs, the Orbis-Sigm...Pediatric valve design; Shunt valves1996
58 Couldwell, William T.Defining postoperative values for successful resection of prolactinomasWe, as other authors, have noted that late relapse of hyperprolactinemia following apparent successful adenomectomy in women harboring microprolactinomas is not rare.[1-3] On retrospective review of a series of tumors treated at the University of Southern California teaching hospitals, we have foun...Hyperprolactinemia; Microadenoma; Prolactin1996
59 Couldwell, William T.Vagus nerve stimulation activates central nervous system structures in epileptic patients during PET H2(15)O blood flow imagingOBJECTIVE: To determine the central areas of activation by vagal nerve stimulation (VNS) in epilepsy. VNS is a promising neurosurgical method for treating patients with partial and secondary generalized epilepsy. The anti-epileptic mechanism of action from VNS is not well understood. METHODS: We p...Epilepsy; Positron emission tomography; Thalamus; Vagus nerve stimulation1996
60 Schmidt, Meic H.Light-emitting diodes as a light source for intraoperative photodynamic therapyTHE DEVELOPMENT OF more cost-effective light sources for photodynamic therapy of brain tumors would be of benefit for both research and clinical applications. In this study, the use of light-emitting diode arrays for photodynamic therapy of brain tumors with Pholofrin porfimer sodium was investiga...Photodynamic therapy; Brain tumors; Brain tumor therapy; Photofrin; LED1996
61 Kestle, John R. W.Effect of hyperventilation on regional cerebral blood flow in head-injured childrenObjectives: To study cerebral blood flow and cerebral oxygen consumption in severe head-injured children and also to assess the effect of hyperventilation on regional cerebral blood flow. Design: Prospective cohort study. Setting: Pediatric intensive care unit at a tertiary-level university childre...Cerebral blood flow; Head injury; Jugular venous oximetry; Xenon computed tomography scan; Head-injured children1997
62 Couldwell, William T.Transmaxillary approach to the anterior cavernous sinus: a microanatomic studyOBJECTIVE: Several approaches to expose the anterior cavernous sinus have been used, such as frontotemporal, orbitofrontal, anterior subtemporal, and various transfacial approaches. In an effort to gain exposure to the anterior cavernous sinus without necessitating a craniotomy or wide transfacial ...Anterior cavernous sinus; Clivus; Cranial base; Maxillary sinus1997
63 Couldwell, William T.Prognostic variables in surgery for skull base meningiomasThe authors have retrospectively analyzed selected surgical and pathological observations made among a group of 20 patients harboring recurrent cranial base meningiomas in an attempt to reveal which factors may be important in predicting tumor recurrence. This cohort was compared with a group of 3...Skull base; Prognostic factor; Recurrence1997
64 Couldwell, William T.Irving S. Cooper (1922-1985): a pioneer in functional neurosurgeryIrving S. Cooper (1922-1985), the son of a salesman, worked his way through high school, college, and medical school to become one of the pioneers in functional neurosurgery. He developed several novel techniques for the surgical management of Parkinson's disease and other crippling movement disord...Functional neurosurgery; Cryosurgery; Dystonia; Movement disorder; Parkinson's disease; Thalamotomy; Tremor; Neurosurgical history1998
65 Schmidt, Meic H.Benzoporphyrin derivative and light-emitting diode for use in photodynamic therapy: applications of space light-emitting diode technologyPhotodynamic therapy (PDT) is a cancer treatment modality that recently has been applied as adjuvant therapy for rain tumors. PDT consists of intravenously injecting a photosensitizer, which preferentially accumulates in tumor ells, into a patient and then activating the photosensitizer with a light...Benzoporphyrin; Photodynamic therapy; Brain tumors; Photofrin1998
66 Couldwell, William T.Transfacet pedicle-sparing approach for thoracic disc removal: cadaveric morphometric analysis and preliminary clinical experienceA number of operative techniques have been described for the treatment of herniated thoracic discs. The transfacet pedicle-sparing approach allows for complete disc removal with limited spinal column disruption and soft-tissue dissection. Fifteen cadaveric spinal columns were used for evaluation of...Thoracic spine; Herniated thoracic discs; Intervertebral disc herniation; Discectomy; Pedicle; Radiculopathy; Myelopathy1998
67 Couldwell, William T.Posterolateral approach for decompression with anterior and posterior fusion: a less invasive surgical technique for stabilization of the thoracic spineThe goals of surgery in unstable thoracic fractures or tumors involving the thoracic spine are neural decompression, correction of deformity, and stabilization. Several different approaches can be used to achieve these goals. The anterior, combined anterior and posterior, and more recently thoraco...Decompression; Thoracic spine; Posterolateral approach1998
68 Dailey, Andrew T.Complement depletion reduces macrophage infiltration and activation during Wallerian degeneration and axonal regenerationAfter peripheral nerve injury, macrophages infiltrate the degenerating nerve and participate in the removal of myelin and axonal debris, in Schwann cell proliferation, and in axonal regeneration. In vitro studies have demonstrated the role serum complement plays in both macrophage invasion and activ...1998
69 Dailey, Andrew T.Intracranial vascular anastomosis using the microanastomotic systemThe authors describe the use of a microanastomotic device to perform intracranial end-to-end vascular anastomoses. Direct end-to-end anastomosis was performed between the superficial temporal artery and branches of the middle cerebral artery (MCA) in three patients. Two patients had moyamoya disease...Microanastomotic system; Intracranial anastomosis; Superficial temporal-middle cerebral artery bypass; Carotid occlusion1998
70 Kestle, John R. W.Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalusOBJECTIVE: Forty percent of standard cerebrospinal fluid shunts implanted for the treatment of pediatric hydrocephalus fail within the first year. Two new shunt valves designed to limit excess flow, particularly in upright positions, were studied to compare treatment failure rates with those for st...Shunt failure; Valve design; Orbis-Sigma valve; Delta valve1998
71 Swallow, Charles E.; Tsuruda, Jay S.; Digre, Kathleen B.; Glaser, Matthew J.; Davidson, H. Christian; Harnsberger, H. RicTerson syndrome: CT evaluation in 12 patients.PURPOSE: Terson syndrome may be overlooked in the acute setting and often requires ophthalmologic intervention to prevent long-term visual loss. In this syndrome, vitreous or retinal hemorrhage results from an abrupt rise in intracranial pressure, leading to retinal venous hypertension and intraocul...Retinal Hemorrhage; Visual Acuity; Vitreous Hemorrhage1998-04
72 Kestle, John R. W.Change in ventricular size and effect of ventricular catheter placement in pediatric patients with shunted hydrocephalusOBJECTIVE: The multicenter, randomized pediatric cerebrospinal fluid shunt valve design trial found no difference in the rate of shunt failure between a standard valve, a siphon-reducing valve (Delta; Medtronic PS Medical, Goleta, CA), and a flow-limiting valve (Orbis Sigma; Cordis, Miami, FL); ho...Shunt failure; Valve design; Ventricular size; Ventricular catheter placement1999
73 Dailey, Andrew T.Modulation of macrophage and microglial responses to axonal injury in the peripheral and central nervous systemsOBJECTIVE: After axonal injury, macrophages rapidly infiltrate and become activated in the mammalian peripheral nervous system (PNS) but not the central nervous system (CNS). We used the dorsal root pathway to study factors that modulate the response of macrophages to degenerating axons in both the ...Axonal injury; Macrophage response; Microglial response; Peripheral nervous system; Lewis rats1999
74 Couldwell, William T.Prolactinomas: focus on indications, outcomes and management of recurrencesAlthough prolactinomas are discovered at autopsy with equal frequency in women and men, they present clinically in women far more often than in men. In children, "in whom they are the most common type of adenoma, prolactinomas are seen more often in girls than in boys. In a series of nearly 400 PRL...Outcome; Pituitary adenoma; Prognosis; Prolactin; Transsphenoidal surgery1999
75 Schmidt, Meic H.Medical applications of space light-emitting diode technology-space station and beyondSpace light-emitting diode (LED) technology has provided medicine with a new tool capable of delivering light deep into tissues of the body, at wavelengths which are biologically optimal for cancer treatment and wound healing. This LED technology has already flown on Space Shuttle missions, and show...Photodynamic therapy; Lutetium Texaphyrin; Lutex; Canine glioma1999
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