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51 Olivera, Baldomero M.Biochemical characterization of ?M-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of ?M-conotoxinsConus snail (Conus) venoms are a valuable source of pharmacologically active compounds; some of the peptide toxin families from the snail venoms are known to interact with potassium channels. We report the purification, synthesis, and characterization of ?M-conotoxin RIIIJ from the venom of a fish-...2010
52 Olivera, Baldomero M.Biochemical studies of ω-conotoxin GVIA; a peptide toxin inhibiting voltage-sensitive Ca++ channelsThe fish-hunting cone snails use their venom to quickly paralyze their more agile prey. In the last few years, our laboratories have carried out a program of analyzing biologically active components present in the fish-hunting cone snail venoms (Cruz et al. 1985; Olivera et al. 1985). We have concen...Conotoxins; Calcium channels; Conus geographus; Venom1987
53 Horvath, Martin P.Biochemistry of Cone Snail toxin activationCone snails use venom to capture prey for food and for defense against predators. The venom is composed of over 100 active peptides that target specific receptors in the nervous system. Several of these peptides have the potential to become medicine for treatment of pain, depression, seizures, and n...biochemistry; horvath; olivera; cone snail; toxin; nmda; elution; buffers; sparse matrix test; protease; protein; purification; neurotoxin; conotoxin2013
54 Seger, Jon; Davidson, Diane W.Biological richness of desertsA desert is "waterless," "treeless," "barren," "remote," "uninteresting," and "presumably uninhabited," according to the authoritative Oxford English Dictionary. The word is derived from deserere, a Latin verb meaning "to leave." In English, to desert is still to "abandon," "forsake," or "fail." Bec...Desert life; Desert biodiversity1995
55 Clayton, Dale H.Biology, ecology, and evolution of chewing liceChewing lice are small, dorsoventrally compressed insects and are parasites of virtually all birds (Fig. 1) and some mammals (Fig. 2). Many chewing lice are host specific, being found on only a single species of host. All chewing lice are permanent ectoparasites and complete their entire life c...Chewing lice2003
56 Sekercioglu, CaganBirding economics: conservation through commodificationIn the long-run, the quality of our birding (and the length of our lists) depends on our success in conserving birds and their habitats. Who would not love to see a Labrador Duck during a pelagic trip, have Carolina Parakeets fly overhead on a CBC, or photograph a Bachman's Warbler foraging in a can...2003-01-01
57 Olivera, Baldomero M.Block of Shaker K+ channels by ĸ-conotoxin PVIIA is state dependentĸ-conotoxin PVIIA is the first conotoxin known to interact with voltage-gated potassium channels by inhibiting Shaker-mediated currents. We studied the mechanism of inhibition and concluded that PVIIA blocks the ion pore with a 1:1 stoichiometry and that binding to open or closed channels is very d...Conotoxins; k-conotoxin PVIIA; Potassium channel blockers; Shaker K+ channels1999
58 Ehleringer, James R.Burning coal seams in southern Utah: a natural system for studies of plant responses to elevated CO2In the Burning Hills and Smoky Mountains of southern Utah (USA), coal deposits exposed to the surface have been ignited by lightning and have been burning for periods of years to over a century. We examined one of these sites, where the below-ground combustion of this low-sulfur coal releases gases ...Coal fires; Elevated CO2; Isotope ratios; Atriplex confertifolia; Salsola iberica; Gutierrezia sarothrae1997
59 Jorgensen, ErikCaenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase and is required for synaptic transmission but not synaptic developmentThe neurotransmitter GABA has been proposed to play a role during nervous system development. We show that the Caenorhabditis elegans gene unc-25 encodes glutamic acid decarboxylase (GAD), the GABA biosynthetic enzyme. unc-25 is expressed specifically in GABAergic neurons. Null mutations in unc-25...1999
60 Jorgensen, ErikCaenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesiclesRab molecules regulate vesicular trafficking in many different exocytic and endocytic transport pathways in eukaryotic cells. In neurons, rab3 has been proposed to play a crucial role in regulating synaptic vesicle release. To elucidate the role of rab3 in synaptic transmission, we isolated and cha...1997
61 Jorgensen, ErikCaenorhabditis elegans unc-49 locus encodes multiple subunits of a heteromultimeric GABA receptorIonotropic GABA receptors generally require the products of three subunit genes. By contrast, the GABA receptor needed for locomotion in Caenorhabditis elegans requires only the unc-49 gene. We cloned unc-49 and demonstrated that it possesses an unusual overlapping gene structure.1999
62 Olivera, Baldomero M.Calcium channel antagonists: ω-conotoxin defines a new high affinity siteThe ω-conotoxins, a class of Ca2+ channel antagonists from fish-hunting marine snails, have recently been described (Olivera, B. M., McIntosh, J. M., Zeikus, R., Gray, W. R., Varga, J., Rivier, J., de Santos, V., and Cruz, L. J. (1985) Science, 230, 1338-1343). One of these peptide neurotoxins...Conotoxins; Calcium channels; Synaptosomes; Neurotoxins1986
63 Yamaguchi, AyakoCall initiation in African clawed frogsSociety for Neuroscience Meeting 2016vocalizations; Xenopus laevis2016
64 Jorgensen, Erik; Schuske, Kimberly R.CAPS and syntaxin dock dense core vesicles to the plasma membrane in neuronsDocking to the plasma membrane prepares vesicles for rapid release. Here, we describe a mechanism for dense core vesicle docking in neurons. In Caenorhabditis elegons motor neurons, dense core vesicles dock at the plasma membrane but are excluded from active zones at synapses.2008
65 Hultine, KevinCarbon and nitrogen allocation to male and female reproduction in Rocky Mountain Douglas-fir (Pseudotsuga menziesii var. glauca, Pinaceae)We measured carbon (respiration, photosynthesis, and production) and nitrogen allocation to male and female cones of Rocky Mountain Douglas-fir (Pseudotsuga menziesii var. glauca) to quantify gender-specific: (1) resource allocation to reproduction, and (2) contribution to carbon costs of reproducti...Gender; photosynthesis; resource allocation2000
66 Ehleringer, James R.Carbon isotope discrimination and water relations of oak hybrid populations in southwestern UtahThe evergreen oak Quercus turbinella and the deciduous Q. gambelii form natural hybrids in southwestern Utah and northern Arizona. Hybrid individuals also are found in northern Utah in a region where only Q. gambelii currently exists, indicating that Q. turbinella has recently retreated southward. ...Quercus turbinella; Oak hybrids; Leaf structure; Leaf nitrogen; Carbon isotope discrimination; Water potential; Oak ecology2000
67 Ehleringer, James R.Carbon isotope discrimination in the C4 shrub Atriplex confertifolia along a salinity gradientCarbon isotope discrimination (∆) was measured for leaves of Atriplex confertifolia along a salinity gradi~ ent in northern Utah. Over this gradient, the variation of ∆ values was high for a C4 species, and the ∆ values were positively correlated with salinity in both years of the study. Of th...Carbon isotope ratio; Salt stress; Bundle sheath leakiness; Halophyte; Atriplex confertifolia; Salinity gradient1995
68 Ehleringer, James R.Carbon isotope dynamics in Abies amabilis stands in the CascadesCarbon isotope ratios (d13C) of canopy air and carbon isotope discrimination at the ecosystem level were studied in three montane Pacific silver fir (Abies amabilis (Dougl. ex Loud.) Dougl. ex J. Forbes) stands, an old-growth and two younger stands. Spatial and temporal variations of canopy CO2 con...Carbon isotopes; Pacific silver fir; Carbon budget; Soil respiration; Cascade Mountains1998
69 Ehleringer, James R.Carbon isotope ratios in belowground carbon cycle processesAnalyses of carbon isotope ratios (δ13C) in soil organic matter (SOM) and soil respired CO2 provide insights into dynamics of the carbon cycle. δ13C analyses do not provide direct measures of soil CO2 efflux rates but are useful as a constraint in carbon cycle models. In many cases, δ13C analyses...Below ground processes; Ecosystems; Carbon cycle; Carbon isotope ratio; Ecosystem processes; Global change; Soil organic carbon; Soil organic matter2000
70 Ehleringer, James R.Carbon isotope ratios of Atacama Desert plants reflect hyperaridity of region in northern ChileLeaf carbon isotope ratios were measured on plants from the coastal portions of the Atacama Desert at Pan de Azucar and Paposo, Chile. Most species possessed C3 photosynthesis, although there were several CAM species, indications of some facultative CAM species, and only one C4 species. The carbon i...Atacama Desert; Carbon isotope ratio; Intercellular carbon dioxide concentration; Hyperaridity1998
71 Sekercioglu, CaganCauses and consequences of bird extinctionsIncreased human domination of the planet has caused the declines and extinctions of countless species. Each species has not only intrinsic value, but ecological functions of organisms are also essential for the integrity of ecosystems that allow people to benefit from essential free ecosystem servic...2003-01-01
72 Torti, Sylvia D.; Coley, Phyllis D.; Kursar, Thomas A.Causes and consequences of monodominance in tropical lowland forestsTropical canopy dominance in lowland, well-drained forests by one plant species is a long-standing conundrum in tropical biology. Research now shows that dominance is not the result of one trait or mechanism. We suggest that the striking dominance of Gilbertiodendron dewevrei in the Ituri Forest of ...Monodominance; Gilbertiodendron dewevrei; Ituri Forest; Understory2001
73 Sperry, John S.Cavitation fatigue - the weakening of cavitation resistance of xylem and its reversibilityXylem function is essential for the growth and survival of higher land plants. Xylem must not only be efficient under favorable conditions to facilitate high rates of stomatal conductance and carbon uptake, but it should also remain functional under drought conditions, when water potential (Ψ) dro...Cavitation fatigue; Drought; Pit membrane2003
74 Davidson, Diane W.Cecropia and its biotic defensesIn all the world, the genus Cecropia is unrivaled for the number of myrmecophytes, or true "antplants" counted among its species (McKey & Davidson, 1993). Based on the proportion of Cecropia species producing Mullerian bodies in at least some parts of their distribution, myrmecophytes comprise the ...Myrmecophytes; Mullerian bodies; Pearl bodies2005
75 Bastiani, MichaelCell-cell interactions during the migration of an identified commissural growth cone in the embryonic grasshopperOne of the fascicles of the posterior commissure of the embryonic grasshopper is pioneered by an individually identifiable neuron named Q1. Q1 initially grows along a longitudinal pathway established by another pioneer neuron, MPl, and then crosses to the midline, where it meets and fasciculates wi...Commissure; Pathfinding; Filopodia1993
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