|
|
Creator | Title | Description | Subject | Date |
26 |
|
Blumenthal, Donald K. | Structure of vardenafil in the active site of PDE5 | PyMol file (725 KB): http://ir.utah.edu/blumenthal/PyMol/PDE5_Vardenafil.pse Download PyMol software to view this file. Available for free educational use: http://pymol.sourceforge.net Quicktime Movie--High Resolution (4 MB): http://stream.lib.utah.edu/index.php?c=details&id=9288 Quicktime Movie--... | Levitra; Phosphodiesterase inhibitors; PDE; Enzymes; Intracellular cyclic nucleotide-mediated signaling; 110634 | 2006-07-14 |
27 |
|
Blumenthal, Donald K. | Structure of Vardenafil in the active site of PDE5 | | | 2006-07-14 |
28 |
|
Blumenthal, Donald K. | CYP2C9 catalytic domain showing positions of *2 and *3 polymorphisms | X-ray crystal structure of human CYP2C9 (PDB id=1R9O (http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1R9O)) showing the positions of the amino acids altered by the CYP2C9*2 (Arg144Cys) and CYP2C9*3 (Ile359Leu) polymorphisms relative to the six substrate recognition sites (SRSs). The Arg144 and Ile359... | Warfarin; CYP2C9*2; CYP2C9*3; P450 | 2006-08-30 |
29 |
|
Keefe, Kristen A. | Introduction to autonomic pharmacology | | | 2006-09-12 |
30 |
|
Blumenthal, Donald K. | Ranolazine: a new antianginal agent with a novel mechanism of action | This animation (with audio) illustrates the mechanism of action of ranolazine (RANEXA), a novel antianginal drug that inhibits the late sodium current (late I Na) in cardiac myocytes. The animation first describes how the late sodium current can contribute to symptoms of myocardial ischemia by causi... | Angina; Myocardial Ischemia, Acute Coronary Syndrome; Voltage-Gated Sodium Channel, Late Sodium Current; Sodium-Calcium Exchanger; Calcium Overload; Ranolazine | 2006-09-19 |
31 |
|
Bernstein, Paul S.; Gellermann, Werner | Nonmydriatic fluorescence-based quantitative imaging of human macular pigment distributions. | We have developed a CCD-camera-based nonmydriatic instrument that detects fluorescence from retinal lipofuscin chromophores ("autofluorescence") as a means to indirectly quantify and spatially image the distribution of macular pigment (MP). The lipofuscin fluorescence intensity is reduced at all ret... | Cytology; Sensitivity and Specificity | 2006-10 |
32 |
|
Bernstein, Paul S. | HPLC measurement of ocular carotenoid levels in human donor eyes in the lutein supplementation era. | PURPOSE: A substantial proportion of the population at risk for visual loss from age-related macular degeneration consumes supplements containing high doses of lutein, but clinical studies to date have shown only modest and variable increases in macular carotenoid pigments in response to supplementa... | Chromatography, High Pressure Liquid; Dietary Supplements; Tissue Donors | 2007-02 |
33 |
|
Blumenthal, Donald K. | In vivo evaluation of the delivery and efficacy of a sirolimus-laden polymer gel for inhibition of hyperplasia in a porcine model of arteriovenous hemodialysis graft stenosis | Synthetic arteriovenous (AV) hemodialysis grafts are plagued by hyperplasia resulting in occlusion and graft failure yet there are no clinically available preventative treatments. Here the delivery and degradation of a sirolimus-laden polymer gel were monitored in vivo by magnetic resonance imaging ... | | 2012-01-01 |