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Creator | Title | Description | Subject | Date |
26 |
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Gerig, Guido | Structural integrity of the uncinate fasciculus in geriatric depression: relationship with age of onset | Background: The uncinate fasciculus connects limbic structures, such as the hippocampus and amygdala, with frontal regions. This study utilized diffusion tensor imaging to examine the structural integrity of the uncinate fasciculus in late-life depression. Method: 18 elderly depressed and 19 elderly... | | 2007-01-01 |
27 |
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Gerig, Guido | Topology preserving atlas construction from shape data without correspondence using sparse parameters | Statistical analysis of shapes, performed by constructing an atlas composed of an average model of shapes within a population and associated deformation maps, is a fundamental aspect of medical imaging studies. Usual methods for constructing a shape atlas require point correspondences across subject... | | 2012-01-01 |
28 |
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Gerig, Guido | Tumor-induced structural radiometric asymmetry in brain images | This paper presents a general framework for analyzing structural and radiometric asymmetry in brain images. In a healthy brain, the left and right hemispheres are largely symmetric across the mid-sagittal plane. Brain tumors may belong to one or both of the following categories: mass-effect, in whic... | | 2001-01-01 |
29 |
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Gerig, Guido | Analysis of longitudinal shape variability via subject specific growth modeling | Statistical analysis of longitudinal imaging data is crucial for understanding normal anatomical development as well as disease progression. This fundamental task is challenging due to the difficulty in modeling longitudinal changes, such as growth, and comparing changes across different populations... | | 2012-01-01 |
30 |
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Gerig, Guido | 3D tensor normalization for improved accuracy in DTI tensor registration methods | This paper presents a method for normalization of diffusion tensor images (DTI) to a xed DTI template, a pre-processing step to improve the performance of full tensor based registration methods. The proposed method maps the individual tensors of the subject image in to the template space based on ma... | | 2012-01-01 |
31 |
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Gerig, Guido | Modeling 4D changes in pathological anatomy using domain adaptation: analysis of TBI imaging using a tumor database | Analysis of 4D medical images presenting pathology (i.e., lesions) is significantly challenging due to the presence of complex changes over time. Image analysis methods for 4D images with lesions need to account for changes in brain structures due to deformation, as well as the formation and deletio... | | 2013-01-01 |
32 |
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Gerig, Guido | Mixed-effects shape models for estimating longitudinal changes in anatomy | | | 2012-01-01 |
33 |
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Gerig, Guido | Multiscale medial shape-based analysis of image objects | Medial representation of a three-dimensional (3-D) object or an ensemble of 3-D objects involves capturing the object interior as a locus of medial atoms, each atom being two vectors of equal length joined at the tail at the medial point. Medial representation has a variety of beneficial properties,... | | 2003-01-01 |
34 |
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Gerig, Guido | Group mean differences of voxel and surface objects via nonlinear averaging | Building of atlases representing average and variability of a population of images or of segmented objects is a key topic in application areas like brain mapping, deformable object segmentation and object classification. Recent developments in image averaging, i.e. constructing an image which is cen... | | 2006-01-01 |
35 |
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Gerig, Guido | Closed and open source neuroimage analysis tools and libraries at UNC | The emergence of open-source libraries and development tools in the last decade has changed the process of academic software development in many ways. In medical image processing and visualization this change is especially evident, also because open source projects are actively furthered by grant fu... | | 2006-01-01 |
36 |
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Gerig, Guido | Correspondence evaluation in local shape analysis and structural subdivision | Regional volumetric and local shape analysis has become of increasing interest to the neuroimaging community due to the potential to locate morphological changes. In this paper we compare three common correspondence methods applied to two studies of hippocampal shape in schizophrenia: correspondence... | | 2007-01-01 |
37 |
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Gerig, Guido | Discrimination analysis using Multi-object statistics of shape and pose | A main focus of statistical shape analysis is the description of variability of a population of geometric objects. In this paper, we present work towards modeling the shape and pose variability of sets of multiple objects. Principal geodesic analysis (PGA) is the extension of the standard technique ... | | 2007-01-01 |
38 |
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Gerig, Guido | Computational anatomy to assess longitudinal trajectory of brain growth | This paper addresses the challenging problem of statistics on images by describing average and variability. We describe computational anatomy tools for building 3-D and spatio-temporal 4-D atlases of volumetric image data. The method is based on the previously published concept of unbiased atlas bui... | | 2006-01-01 |
39 |
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Gerig, Guido | Statistical shape analysis of Multi-Object complexes | An important goal of statistical shape analysis is the discrimination between populations of objects, exploring group differences in morphology not explained by standard volumetric analysis. Certain applications additionally require analysis of objects in their embedding context by joint statistical... | | 2007-01-01 |
40 |
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Gerig, Guido | Statistics of populations of images and its embedded objects: driving applications in neuroimaging | Work in progress towards modeling shape statistics of multi-object complexes is presented. Constraints defined by the set of objects such as a compact representation of object shape relationships and correlation of shape changes might have advantages for automatic segmentation and group discriminati... | | 2006-01-01 |
41 |
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Gerig, Guido | Statistical shape analysis of brain structures using spherical wavelets | We present a novel method of statistical surface-based morphometry based on the use of non-parametric permutation tests and a spherical wavelet (SWC) shape representation. As an application, we analyze two brain structures, the caudate nucleus and the hippocampus, and compare the results obtained to... | | 2007-01-01 |
42 |
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Gerig, Guido | Statistical group differences in anatomical shape analysis using Hotelling T2 Metric | Shape analysis has become of increasing interest to the neuroimaging community due to its potential to precisely locate morphological changes between healthy and pathological structures. This manuscript presents a comprehensive set of tools for the computation of 3D structural statistical shape anal... | | 2007-01-01 |
43 |
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Gerig, Guido | Regional gray matter growth, sexual dimorphism, and cerebral asymmetry in the Neonatal Brain | Although there has been recent interest in the study of childhood and adolescent brain development, very little is known about normal brain development in the first few months of life. In older children, there are regional differences in cortical gray matter development, whereas cortical gray and wh... | | 2007-01-01 |
44 |
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Gerig, Guido | Evaluation of DTI property maps as basis of DTI atlas building | Compared to region of interest based DTI analysis, voxel-based analysis gives higher degree of localization and avoids the procedure of manual delineation with the resulting intra and inter-rater variability. One of the major challenges in voxel-wise DTI analysis is to get high quality voxel-level c... | | 2010-01-01 |
45 |
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Gerig, Guido | Quality control of diffusion weighted images | Diffusion Tensor Imaging (DTI) has become an important MRI procedure to investigate the integrity of white matter in brain in vivo. DTI is estimated from a series of acquired Diffusion Weighted Imaging (DWI) volumes. DWI data suffers from inherent low SNR, overall long scanning time of multiple dire... | | 2010-01-01 |
46 |
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Gerig, Guido | Multivariate longitudinal statistics for neonatal-pediatric brain tissue development | The topic of studying the growth of human brain development has become of increasing interest in the neuroimaging community. Cross-sectional studies may allow comparisons between means of different age groups, but they do not provide a growth model that integrates the continuum of time, nor do they ... | | 2008-01-01 |
47 |
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Gerig, Guido | Towards analysis of growth trajectory through multi-modal longitudinal MR imaging | The human brain undergoes significant changes in the first few years after birth, but knowledge about this critical period of development is quite limited. Previous neuroimaging studies have been mostly focused on morphometric measures such as volume and shape, although tissue property measures rela... | | 2010-01-01 |
48 |
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Gerig, Guido | A new framework for analyzing white matter maturation in early brain development | The trajectory of early brain development is marked by rapid growth presented by volume but also by tissue property changes. Capturing regional characteristics of axonal structuring and myelination via neuroimaging requires analysis of longitudinal image data with multiple modalities. Complementary ... | | 2010-01-01 |
49 |
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Gerig, Guido | Changes of MR and DTI appearance in early human brain development | Understanding myelination in early brain development is of clinical importance, as many neurological disorders have their origin in early cerebral organization and maturation. The goal of this work is to study a large neonate database acquired with standard MR imagery to illuminate effects of early ... | | 2010-01-01 |
50 |
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Gerig, Guido | Cortical enhanced tissue segmentation of neonatal brain MR images acquired by a dedicated phased array coil | The acquisition of high quality MR images of neonatal brains is largely hampered by their characteristically small head size and low tissue contrast. As a result, subsequent image processing and analysis, especially for brain tissue segmentation, are often hindered. To overcome this problem, a dedic... | | 2009-01-01 |