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26 Olson, Randall J.Comparison of patient satisfaction after uncomplicated cataract surgery between the silicone AMO SI-30/40 and the acrylic Alcon MA30BA and MA60BA foldable intraocular lensesPURPOSE: To compare patient satisfaction with vision 12 months after implantation of a silicone or acrylic foldable intraocular lens (IOL). SETTING: John A. Moran Eye Center, University of Utah Medical Center, Salt Lake City, Utah, USA. METHODS: Selection criteria included patients who had uneventfu...Patient Satisfaction; Lenses, Intraocular; Silicone Elastomers; Biocompatible Materials2001-10
27 Baehr, WolfgangIdentification and light-dependent translocation of a cone-specific antigen, (Cone Arrestin) recognized by monoclonal antibody 7G6PURPOSE: To elucidate the antigen recognized by monoclonal antibody (mAb) 7G6, a widely used cone-specific marker. METHODS: 7G6 immunocytochemistry was performed on sections of human, primate, and bovine retina. The antigen was immunoprecipitated from human retinal lysates and purified with protein ...Cones (Retina); Molecular Sequence Data; Phototransduction2003
28 Bernstein, Paul S.; Zabriskie, Norman A.; Zhang, Kang; Leppert, Mark F.Diverse macular dystrophy phenotype caused by a novel complex mutation in the ELOVL4 genePURPOSE: A 5-bp deletion in ELOVL4, a photoreceptor-specific gene, has been associated with autosomal dominant (ad) macular dystrophy phenotypes in five related families, in which phenotypes range from Stargardt-like macular dystrophy (STGD3; Mendelian Inheritance in Man 600110) to pattern dystrophy...Linkage (Genetics); Middle Older people; Phenotype2001
29 Digre, Kathleen B.; Blumenthal, Deborah T.; Cessna, Melissa H.; Gopez, Evelyn V.; Shen, YueCarcinomatous meningitis as the presenting manifestation of gallbladder carcinoma: case report and review of the literatureThe primary tumors that typically cause carcinomatous meningitis include lung cancer, breast cancer, leukemia, lymphoma and melanoma. A variety of neurological signs and symptoms can be seen depending on the extent and location of the meningeal metastasis. Once the diagnosis of carcinomatous meningi...Carcinomatous Meningitis; Gallbladder Carcinoma; Leptomeningeal Metastasis; Meningeal Carcinomatosis; Cranial Neuropathy2004-10
30 Zhang, KangIdentification and functional consequences of a new mutation (E155G) in the gene for GCAP1 that causes autosomal dominant cone dystrophy2001
31 Baehr, Wolfgang; Frederick, Jeanne M.; Church-Kopish, Jill; Howes, KimberlyMutant rhodopsin transgene expression on a null backgroundPURPOSE. To study mechanisms leading to photoreceptor degeneration in mouse models for autosomal dominant retinitis pigmentosa (adRP) based on the rhodopsin P23H mutation. METHODS. Mice of a transgenic line expressing a rhodopsin triple mutant, V20G, P23H, and P27L (GHL), were mated with rhodopsin (...Mutant Rhodopsin; Photoreceptor Degeneration; Autosomal Dominant Retinitis Pigmentosa; Rhodopsin2001-03
32 Askew, Eldon W.; Bernstein, Paul S.Serum and macular responses to antioxidant supplementation verus a carotenoid-rich dietary intervention in the elderly.The aim of this study was to observe responses of serum antioxidants, oxidative stress biomarkers, and macular carotenoid pigments to antioxidant supplements or dietary intervention in a single-masked, randomized, pilot clinical study of elderly subjects receiving antioxidant supplements or a dietar...Macula; Serum Carotenoids; Zeaxanthin2006-02-01
33 Normann, Richard A.; Johansson,Torbjorn; Abbasi, Masoud; Huber, Robert J.Three-dimensional architecture for a parallel processing photosensing arrayA three-dimensional architecture for a photosensing array has been developed. This silicon based architecture consists of a 10 x 10 array of photosensors with 80 microns diameter, through chip interconnects to the back side of a 500 microns thick silicon wafer. Each photosensor consists of a 300 x 3...Retina; Optics; Silicon; Photosensing1992
34 Normann, Richard A.; Jones, Kelly E.Advanced demultiplexing system for physiological stimulationA CMOS very large scale integration (VLSI) chip has been designed and built to implement a scheme developed for multiplexing/demultiplexing the signals required to operate an intracortical stimulating electrode array. Because the use of radio telemetry in a proposed system utilizing this chip may im...Electrode Array; Stimulation; Telemetry; Microelectrodes; Transistors1997
35 Creel, Donnell J.; Leventhal, Audie G.Retinal projections in tyrosinase-negative albino catsRetinal projections were examined in two tyrosinase-negative albino cats using autoradiographic techniques. Cats from this colony have pink eyes; their retinal pigment epithelium, ciliary body, and iris epithelium are completely devoid of melanin pigment. Test breeding for five generations indicates...Cats; Albinism; Vision; Autoradiography; Retina1982-07
36 Zhang, Kang; Yang, Zhenglin; Jiang, LiMutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11qFamilial exudative vitreoretinopathy (FEVR) is an inherited blinding disorder of the retinal vascular system. Autosomal dominant FEVR is genetically heterogeneous, but its principal locus, EVR1, is on chromosome 11q13-q23. The gene encoding the Wnt receptor frizzled-4 (FZD4) was recently reported ...Familial exudative vitreoretinopathy; FEVR; Inherited blinding disorders2004
37 Baehr, Wolfgang; Zhang, Kang; Kolb, HelgaGene array and expression of mouse retina guanylate cyclase activating proteins 1 and 2PURPOSE: To identify gene arrangement, chromosomal localization, and expression pattern of mouse guanylate cyclase activating proteins GCAP1 and GCAP2, retina-specific Ca2+-binding proteins, and photoreceptor guanylate cyclase activators. METHODS: The GCAP1 and GCAP2 genes were cloned from genomic l...Molecular Sequence Data; Guanylate Cyclase-Activating Proteins; In Situ Hybridization, Fluorescence1998
38 Normann, Richard A.; Kolb, Helga; Lasater, Eric M.Signal integration at the pedicle of turtle cone photoreceptors: an anatomical and electrophysiological studyThe morphology of the axon which connects the cell body and pedicle of turtle cone photoreceptors was studied by light and electron microscopy. The axon which contains numerous synaptic vesicles, some endoplasmic reticulum, and a few cisternae is basically filled with cytoplasm. The length of the ax...Cone Photoreceptor, Voltage Clamp; Isolated Cells; Input Resistance; Cell Body-Pedicle Coupling1989
39 Baehr, WolfgangCalcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neuronsThe second messengers cAMP and inositol-1,4,5-triphosphate have been implicated in olfaction in various species. The odorant-induced cGMP response was investigated using cilia preparations and olfactory primary cultures. Odorants cause a delayed and sustained elevation of cGMP. A component of this c...Calcium-Binding Proteins; Nerve Tissue Proteins; Rats, Sprague-Dawley1998
40 Normann, Richard A.; Muller, Jay F.; Kolb, HelgaSynaptic inputs to physiologically defined turtle retinal ganglion cellsTwo physiologically distinct, HRP-marked turtle retinal ganglion cells were examined for their morphology, GABAergic, glycinergic, and bipolar cell synaptic inputs, using electron-microscopic autoradiography and postembedding immunocytochemistry. One cell was a color-opponent, transient ON/OFF gangl...Turtles; Neural Pathways; Synapes; Retinal Ganglion Cells1991
41 Olson, Randall J.; Pingree, Michael F.; Lundergan, Maureen K.Penetrating keratoplasty for keratoconus: a long-term review of results and complicationsPURPOSE: To study the long-term complications of penetrating keratoplasty (PKP) to evaluate current recommendations to patients with keratoconus. SETTING: John Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS: Retrospective study of all PKP procedures for keratoconus performe...Visual Acuity; Refraction, Ocular; Keratoconus; Astigmatism2000-07
42 Olson, Randall J.; Mamalis, Nick; Spencer, Terrence S.Postoperative sterile endophthalmitis (TASS) associated with the memorylensPURPOSE: To report 10 cases of delayed-onset acute intraocular inflammation following cataract extraction and posterior chamber implantation of the MemoryLens(R) intraocular lens (IOL). SETTING: John A. Moran Eye Center, Department of Ophthalmology, University of Utah, Salt Lake City, Utah, USA. MET...Memory Lens; Toxic Anterior Segment Syndrome; Retrospective Studies; adverse effects2000-12
43 Normann, Richard A.Background and bleaching adaptation in luminosity type horizontal cells in the isolated turtle retina1. The effects of background illumination and bleached photopigment on luminosity type horizontal cells were studied in the isolated turtle retina. 2. Background illumination, which produced less than 60% bleaching, hyperpolarized and desensitized the horizontal cells to a degree which depended upon...Turtles; Retina; Photoreceptors; Bleached photopigment; Dark Adaptation1990
44 Baehr, WolfgangGuanylyl cyclase activating protein. A calcium-sensitive regulator of phototransductionGuanylyl cyclase activating protein (GCAP1) has been proposed to act as a calcium-dependent regulator of retinal photoreceptor guanylyl cyclase (GC) activity. Using immunocytochemical and biochemical methods, we show here that GCAP1 is present in rod and cone photoreceptor outer segments where photo...Cloning, Molecular; DNA Primers; Molecular Sequence Data1995
45 Olson, Randall J.Wound complications associated with incision enlargement for foldable intraocular lens implantation during cataract surgeryPURPOSE: To determine the relationship between various intraocular lens (IOL) types and the incidence of unwanted light images. SETTING: The Moran Eye Center, University of Utah, Salt Lake City, Utah, USA. METHODS: A telephone questionnaire was administered to 302 postoperative patients who had rece...Cararact Surgery; Incision Enlargement; Wound Complications; Vision Disorders2000-06
46 Normann, Richard A.; Shah, Maulik R.Study of printed spiral coils for neuroprosthetic transcranial telemetry applicationsWe have explored the use of printed spiral coils (PSC's) for neuroprosthetic transcranial telemetry applications. We fabricated two-dimensional PSC's on a thin (25 microns) polyimide substrate using copper (35 microns) as a conducting material. All the coils had a fixed inner diameter of 1.0 cm. We ...Blindness; Neuroprosthesis; Transcranial Telemetry System; Prosthesis Design1998
47 Bernstein, Paul S.Evaluation of the G protein coupled receptor-75 (GPR75) in age related macular degeneration2001
48 Bernstein, Paul S.Biochemical characterization of the retinoid isomerase system of the eyeWe have previously shown that membranes from the retinal pigment epithelium can transform added all-trans-retinol into a mixture of 11-cis-retinoids, demonstrating the "missing reaction" in the visual cycle for the first time (Bernstein, P. S., Law, W. C., and Rando, R. R. (1987) Proc. Natl. Acad. S...Hydrogen-Ion Concentration1987
49 Olson, Randall J.Update on a long-term, prospective study of capsulotomy and retinal detachment rates after cataract surgeryPURPOSE: To evaluate the retinal detachment risks and neodymium:YAG (Nd:YAG) capsulotomy rates associated with different cataract approaches and intraocular lens (IOL) styles in a long-term,prospective clinical study. SETTING: Clinical practice of 1 ophthalmologist, Fort Collins, Colorado, USA. METH...Cataract Extraction; Laser Therapy; Retinal Detachment; Risk Factors2000-07
50 Fu, YingbinMechanism of reductive activation of potato tuber ADP-glucose pyrophosphorylase.The potato tuber (Solanum tuberosum L.) ADP-glucose pyrophosphorylase activity is activated by a incubation with ADP-glucose and dithiothreitol or by ATP, glucose- 1-phosphate, Ca2+, and dithiothreitol. The activation was accompanied by the appearance of new sulfhydryl groups as determined with 5, 5...Glucosephosphates; Enzyme Activation; Adenosine Triphosphate1998
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