|
|
Creator | Title | Description | Subject | Date |
| 26 |
 |
Couldwell, William T. | Development of neurosurgery in Southern California and the Los Angeles County/University of Southern California Medical Center | The Los Angeles County General Hospital has played an integral role in the development of medicine and neurosurgery in Southern California. From its fledgling beginnings, the University of Southern California School of Medicine has been closely affiliated with the hospital, providing the predomina... | Historical vignette; Los Angeles County General Hospital; University of Southern California School of Medicine; Neurosurgical history | 1993 |
| 27 |
 |
Kestle, John R. W. | Moyamoya phenomenon after radiation for optic glioma | The role of radiotherapy in the management of patients with optic pathway glioma is controversial. In a series of patients with optic pathway glioma treated at The Hospital for Sick Children in Toronto, five children were encountered who developed moyamoya phenomenon after radiotherapy. A retrospec... | Optic pathway glioma | 1993 |
| 28 |
 |
Dailey, Andrew T. | Emergent aneurysm clipping without angiography in the moribund patient with intracerebral hemorrhage: the use of infusion computed tomography scans | THE AUTHORS REPORT their experience with 25 patients (mean age, 44.3 ± 12.1 years) with an intracerebral hematoma (ICH) from a ruptured aneurysm who were emergently operated on without angiography. Instead, preoperative high-resolution infusion computed tomography (CT) scans were used to identify... | Ruptured aneurysms; Computed tomography; Infusion computed tomography; Aneurysm clipping | 1993 |
| 29 |
 |
Kestle, John R. W. | Role of angiography following aneurysm surgery | The postoperative angiograms in 66 patients who underwent craniotomy for clipping of 78 cerebral aneurysms were reviewed. Indications for urgent postoperative angiography included neurological deficit or repeat subarachnoid hemorrhage. Routine postoperative angiograms were carried out in the remai... | Postoperative angiography; Aneurysm rest; Cerebral angiography; Vascular occlusion | 1993 |
| 30 |
 |
Schmidt, Meic H. | Photodynamic therapy | We appreciate the comments of Drs. Kaye and Hill on our article. We are pleased that these investigators concurred with our impression that photodynamic therapy (PDT) may potentially be useful in the treatment of posterior fossa tumors. Several interesting questions were raised about the technical ... | Photodynamic therapy; Photofrin | 1994 |
| 31 |
 |
Couldwell, William T. | Surgical implications of magnetic resonance-enhanced dura | THE PURPOSE OF this study was to assess tissue changes responsible for dural enhancement on magnetic resonance imaging (MRI) and its clinical implications. A prospective surgical, histopathological, and MRI study was performed in 7 3 patients with various types of disease, including meningiomas (n =... | Enhanced dura | 1994 |
| 32 |
 |
Couldwell, William T. | Surgical approaches to petroclival meningiomas Part II: extended approaches | In Part I, the classification, clinical presentation, and upper and midclival surgical approaches were discussed. This lesson covers extended surgical approaches, results, complications, and adjuvant therapy. | Petroclival meningiomas; Petroclivus; Surgical approach; Staged surgery; Complications; Adjuvant therapy; Radiosurgery; Resections | 1994 |
| 33 |
 |
Couldwell, William T. | Hypericin: a potential antiglioma therapy | HYPERICIN, A POLYCYCLIC aromatic dione isolated from plants, is presently being clinically evaluated as an antiviral agent in the treatment of human immunodeficiency virus (HIV) infection. In addition, it is known to be a potent protein kinase C inhibitor. To evaluate its potential as an inhibitor o... | Hypericin; Protein kinase C; Glioma; Brain neoplasm | 1994 |
| 34 |
 |
Couldwell, William T. | Comment on: Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials | The long-term consequences of adenovirus-mediated conditional cytotoxic gene therapy for gliomas remain uncharacterized. We report here detection of active brain inflammation 3 months after successful inhibition of syngeneic glioma growth. The inflammatory infiltrate consisted of activated macrophag... | Brain inflammation; Herpes simplex virus-1; Thymidine kinase; Syngeneic glioma; Adenovirus-mediated gene therapy | 1994 |
| 35 |
 |
Kestle, John R. W. | Effect of single-application topical ophthalmic anesthesia in patients with trigeminal neuralgia: a randomized double-blind placebo-controlled trial | To evaluate the reported benefit of ipsilateral single-application ophthalmic anesthetic eyedrops in patients with typical trigeminal neuralgia, a randomized double-blind placebo-controlled trial was performed. Fortyseven patients were randomly assigned to receive two drops of either proparacaine (... | Randomized trial; Ophthalmic anesthesia | 1994 |
| 36 |
 |
Couldwell, William T. | Protein kinase C and growth regulation in malignant gliomas | To the Editor: The presence of amplified growth factor systems in many tumor models, including malignant gliomas, raises the question of how such external signals are transduced into a transformed phenotype (increased proliferation, invasion, lack of contact inhibition, angiogenic capacity, etc.). ... | Protein kinase C; Glioma; Brain neoplasm; protooncogenes; Apoptosis; Tamoxifen | 1994 |
| 37 |
 |
Couldwell, William T. | Cranioplasty with the Medpor porous polyethylene Flexblock implant | The authors describe the use of a porous polyethylene Flexblock implant for cosmetic cranioplasty. The implant may be used to cover any small- or medium-sized (< 8 cm) cranial defect, offering similar cosmetic results to standard alloplast cranioplasty while decreasing operation time. The porous i... | Cranioplasty; Medpor; Alloplast; Polyethylene; Skull defect | 1994 |
| 38 |
 |
Couldwell, William T. | Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report | LEVAMISOLE AND 5-FLUOROURACIL have now become the standard chemotherapeutic regimen for patients with Stage 111 colon carcinoma. A case of multifocal inflammatory leukoencephalopathy secondary to levamisole alone or combination of levamisole and 5-fluorouracil is reported. Magnetic resonance imaging... | Autopsy; Levamisole; Multifocal inflammatory leukoencephalopathy | 1994 |
| 39 |
 |
Couldwell, William T. | Surgical approaches to petroclival meningiomas part I: upper and midclival approaches | Strictly considered, petroclival meningiomas represent only a percentage of the 10% of all intracranial meningiomas that reside in the posterior fossa. Although not statistically frequent, with their location in proximity to cranial nerves, the basilar artery and its perforating branches, and t... | Petroclival meningiomas; Petroclivus; Surgical approach; Upper clivus; Midclivus | 1994 |
| 40 |
 |
Couldwell, William T. | Management of pituitary adenomas | We present an overview of the management of pituitary adenomas, with discussions of microanatomy, of diagnostic studies of general neuroendocrine function, and of radiologic evaluation. We discuss the diagnosis of pituitary adenoma and its treatment with sections on null cell, prolactin (PRL)-secre... | Pituitary adenoma; Transsphenoidal surgery; Corticotropin; Prolactin; Growth hormone; Transcranial surgery | 1994 |
| 41 |
 |
Kestle, John R. W. | Relationship of intraoperative electrophysiological criteria to outcome after selective functional posterior rhizotomy | At British Columbia's Children's Hospital, the criteria used in selective functional posterior rhizotomy (SFPR) evolved in three distinct phases. In Phase 1 the electrophysiological criteria for abnormality included a low threshold to a single stimulation, a sustained response to 50-Hz stimulation, ... | Selective posterior rhizotomy; Electrophysiological criteria; Intraoperative electrical stimulation | 1995 |
| 42 |
 |
Kestle, John R. W. | Simple risk predictions for arteriovenous malformation hemorrhage | WE PRESENT A simple risk prediction formula for arteriovenous malformation hemorrhage. Natural history studies have shown an annual risk of hemorrhage of 2 to 4% for patients with brain arteriovenous malformations. Although decision analysis programs and biostatistical models are available to predic... | Arteriovenous malformation; Hemorrhage risk; Prediction formula | 1995 |
| 43 |
 |
Couldwell, William T. | Paradoxical elevation of Ki-67 labeling with protein kinase inhibition in malignant gliomas | The monoclonal antibody Ki-67 recognizes a nuclear antigen expressed in the G1, S, G2, and M phase of the cell cycle and has been used extensively as an indicator of cellular proliferation in malignant gliomas, both in the laboratory and clinically. Recently, protein kinase C (PKC) inhibitors have b... | Brain neoplasm; Chemotherapy; Glioma; Monoclonal antibody; Ki-67; Protein kinase C; Tamoxifen | 1995 |
| 44 |
 |
Couldwell, William T. | Pallidotomy in advanced Parkinson's disease | To the Editor: We read with interest the comments published regarding our recent article on pallidotomy in patients with advanced Parkinson's disease (3). There seems to be confusion as to some of the technical methods used in creating the radiofrequency lesions in these patients. As noted in the Pa... | Pallidotomy; Dyskinesia | 1995 |
| 45 |
 |
Kestle, John R. W. | Natural history of cerebral cavernous malformations | To determine the natural history of brain cavernous malformations, the authors entered patients referred to their center into a prospective registry between 1987 and 1993. All patients underwent magnetic resonance imaging, which showed the typical appearance of this lesion, and conservative manageme... | Cavernous malformation; Vascular malformation; Seizure | 1995 |
| 46 |
 |
Dailey, Andrew T. | Pathophysiology of oral pharyngeal apraxia and mutism following posterior fossa tumor resection in children | Mutism following posterior fossa tumor resection in pediatric patients has been previously recognized, although its pathophysiology remains unclear. A review of the available literature reveals 33 individuals with this condition, with only a few adults documented in the population. All of these pati... | Vermis; Posterior fossa tumor; Pediatric patients | 1995 |
| 47 |
 |
Kestle, John R. W. | Reduction of hemorrhage risk after stereotactic radiosurgery for cavernous malformations | The benefits of radiosurgery for cavernous malformations are difficult to assess because of the unclear natural history of this vascular lesion, the inability to image malformation vessels, and the lack of an imaging technique that defines "cure." The authors selected for radiosurgery 47 patients w... | Cavernous malformation; Gamma knife; Stereotactic radiosurgery | 1995 |
| 48 |
 |
Couldwell, William T. | Ventroposterior medial pallidotomy in patients with advanced Parkinson's disease | IN A PRELIMINARY study, the effects of ventroposterior medial pallidotomy were evaluated in five patients with advanced Parkinson's disease in whom medical therapy had failed. The mean age was 67.0 ? 5.6 years, and t h e mean Hoelin and Yahr stage when "off" was 3.9 ? 1.3. Three patients received u... | Pallidotomy; Dyskinesia; Stereotaxy; Postoperative morbidity | 1995 |
| 49 |
 |
Dailey, Andrew T. | Magnetic resonance neurography for cervical radiculopathy: a preliminary report | MAGNETIC RESONANCE NEUROGRAPHY was used to directly image cervical spinal nerves in patients with clinical and radiographic evidence of cervical radiculopathy. A magnetic resonance imaging phased-array coil system was used to obtain high-resolution coronal T1-weighted spin echo, coronal/axial T2-wei... | | 1996 |
| 50 |
 |
Kestle, John R. W. | Value of postoperative surveillance imaging in the management of children with some common brain tumors | The rationale for obtaining surveillance computerized tomography (CT) scans or magnetic resonance (MR) images in pediatric patients with brain tumors is that early detection of recurrence may result in timely treatment and better outcome. The purpose of this study was to investigate the value of sur... | Brain neoplasm; Brain tumors; Computerized tomography scanning; Surveillance; Postoperative surveillance | 1996 |
