Filters: Department: "Biology" School Or College: "College of Science" Collection: "ir_uspace" Format: "application/pdf"
| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 426 |
 |
Capecchi, Mario R. | Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. | Mutations were targeted to the Hprt locus of mouse embryo-derived stem cells by using 22 different sequence replacement and sequence insertion vectors. The targeting frequency was examined at two sites within the Hprt locus as a function of the extent of homology between the targeting vector and the... | Cell Line; DNA Transposable Elements; Embryo; Exons; Mice | 1992-08-12 |
| 427 |
 |
Thomas, Kirk R.; Capecchi, Mario R. | Efficient correction of mismatched bases in plasmid heteroduplexes injected into cultured mammalian cell nuclei. | Heteroduplexes were prepared from two plasmids, pRH4-14/TK and pRH5-8/TK, containing different amber mutations in the neomycin resistance gene (Neor). The Neor gene was engineered to be expressed in both bacterial and mammalian cells. A functional Neor gene conferred kanamycin resistance to bacteria... | Cell Nucleus; Cells, Cultured; Microinjections | 1985-01 |
| 428 |
 |
Olivera, Baldomero M.; Gray, William Robert | New family of Conus peptides targeted to the nicotinic acetylcholine receptor | In this work, a new family of Conus peptides, the αA-conotoxins, which target the nicotinic acetylcholine receptor, is defined. The first members of this family have been characterized from the eastern Pacific species, Conus purpurascens (the purple cone); three peptides that cause paralysis in fis... | Conotoxins; Conus peptides; Conus purpurascens; Purple cone snail | 1995 |
| 429 |
 |
Clayton, Dale H. | Two new species of Dennyus (Ctenodennyus) lice (Phthiraptera: Menoponidae) from swiftlets (Apodiformes: Apodidae) | To date, only a single species of Dennyus (Ctenodennyus) has been described, this being D. (C.) spiniger Ewing from Cypseloides niger borealis (Kennedy), the northern black swift in North America. Through extensive collecting of lice by the junior author from swiftlets and through a loan of Bishop M... | Apodidae; Menoponidae; Ctenodennyus; Dennyus spiniger; Dennyus southwoodi; Dennyus elbeli | 1997 |
| 430 |
 |
Coley, Phyllis D.; Lokvam, John; Kursar, Thomas A. | Allelochemic function for a primary metabolite: the case of L-tyrosine hyper-production in Inga umbellifera (Fabaceae) | Young leaves of tropical forest trees experience far higher herbivory pressure than mature leaves of the same species. Selection on young leaves has led to diverse forms of defense chemical expression. Though most allelochemicals are secondary metabolites, allelochemic function for a primary metabol... | 5-amino-4-hydroxy-pentanoic acid; Panama; Barro Colorado Island; Fabaceae; Inga umbellifera; Primary metabolite; Heliothis virescens | 2006 |
| 431 |
 |
Clayton, Dale H. | Experimental test of the importance of preen oil in Rock Doves (Columba livia) | Most species of birds have a uropygial gland, also known as a preen gland, which produces oil that birds spread through their plumage when preening. The plumage of waterfowl deprived of uropygial oil becomes brittle and is subject to breakage. | Columba livia; Columbiformes; Preen oil; Ectoparasites; Columbicola columbae; Campanulotes compare; Plumage | 2003 |
| 432 |
 |
Shapiro, Michael D. | Limb diversity and digit reduction in reptilian evolution | The study of morphological rules, or trends, offered classical biologists the opportunity to address the mechanisms underlying the evolution of anatomical designs. Regularities in evolution suggested that common functional or developmental rules governed the transformation of structures. Parallelism... | Digit loss; Morphology; Adaptation | 2006 |
| 433 |
 |
Bastiani, Michael | Loss of axons in the cat optic nerve following fetal unilateral enucleation: an electron microscopic analysis | Between the 48th day of gestation (E-48) and maturity, the number of axons in the cat optic nerve is reduced by approximately 50%. On the basis of an electron microscopic assay, the axon population of the E-48 nerve was estimated to be 328,000. In contrast, estimates from two normal adults were 159,... | Ganglion cell death; Retinofugal projection; Retinal ganglion cell axons | 1983 |
| 434 |
 |
Adler, Frederick R. | Patterns of patch rejection in size-structured populations: beyond the ideal free distribution and size segregation | We examine optimal patch allocation strategies in a population structured by size or some other characteristic. By treating size-specific differences among patches as limiting factors, we create a single framework to analyse foraging for two resources, foraging in the presence of predators and fo... | Foraging-predation trade-off; Optimal foraging; Size structure | 2001 |
| 435 |
 |
Ehleringer, James R. | Ecosystem physiology responses to global change | Most ecosystems exposed to double ambient C02 show higher peak season net carbon uptake than those growing at current-ambient C02. For grasslands, above-ground biomass increased by an average of 14%, although individual responses for a given system and year range from negative to +85%. The wide ran... | Global change ; Ecosystem physiology; Carbon budget; Temperature; Water availability; Nitrogen deposition; Ozone | 1999 |
| 436 |
 |
Olivera, Baldomero M. | On the mechanism of the polynucleotide joining reaction | Polynucleotide-joining enzymes (ligases) have been identified in uninfected and phage-infected Escherichia coli (Gellert, 1967; Olivera and Lehman, 1967a; Zimmerman et al., 1967; Gefter et al., 1967; Weiss and Richardson, 1967a; Cozzarelli et al., 1967). Both types of enzyme catalyze the synthesis o... | Enzyme-AMP; Enzyme-Adenylate; DNA-Adenylate; Poly dt-Adenylate; Pyrophosphate bond | 1968 |
| 437 |
 |
Davidson, Diane W. | Evolutionary ecology of symbiotic ant-plant relationships | Abstract.--A tabular survey of ant-plant symbioses worldwide summarizes aspects of the evolutionary ecology of these associations. Remarkable similarities between ant-plant symbioses in disjunct tropical regions result from convergent and parallel evolution of similarly preadapted ants and plants. ... | Symbioses; Evolution; Taxonomic | 1993 |
| 438 |
 |
Goller, Franz | Nonlinear model predicts diverse respiratory patterns of birdsong | A central aspect of the motor control of birdsong production is the capacity to generate diverse respiratory rhythms, which determine the coarse temporal pattern of song. The neural mechanisms that underlie this diversity of respiratory gestures and the resulting acoustic syllables are largely unkn... | Sound; Syllables; Song | 2006 |
| 439 |
 |
Olivera, Baldomero M. | T-superfamily of conotoxins | We report the discovery and initial characterization of the T-superfamily of conotoxins. Eight different T-superfamily peptides from five Conus species were identified; they share a consensus signal sequence, and a conserved arrangement of cysteine residues (- -CC- -CC-). T-superfamily peptides... | Conotoxins; T-superfamily | 1999 |
| 440 |
 |
Olivera, Baldomero M. | Defining a clade by morphological, molecular, and toxinological criteria: distinctive forms related to Conus praecellens A. Adams, 1854 (Gastropoda: Conidae) | We carried out a definition of the Conus praecellens A. Adams, 1854, species group using a combination of comparative morphological data, molecular phylogeny based on standard genetic markers, and toxinological markers. Prior to this work, Conus praecellens was generally postulated to belong to a cl... | Turriconus; 12SrRNA sequences; Phylogenetic analysis; Conus praecellens; Exogenes | 2010 |
| 441 |
 |
Sperry, John S. | Observations of reaction fibers in leaves of dicotyledons | HALLE, OLDEMAN, AND TOMLINSON (1978) have discussed the transference of function between compound leaves and plagiotropic branches in the context of tree architecture. In trees conforming to Cook's model (see Halle, Oldeman, & Tomlinson, 1978), plagiotropic branches resemble compound leaves in their... | Reaction fibers; Compound leaves | 1982 |
| 442 |
 |
Olivera, Baldomero M. | Biochemical characterization of ?M-RIIIJ, a Kv1.2 channel blocker: evaluation of cardioprotective effects of ?M-conotoxins | Conus snail (Conus) venoms are a valuable source of pharmacologically active compounds; some of the peptide toxin families from the snail venoms are known to interact with potassium channels. We report the purification, synthesis, and characterization of ?M-conotoxin RIIIJ from the venom of a fish-... | 2010 | |
| 443 |
 |
Olivera, Baldomero M.; Yoshikami, Doju; Bulaj, Grzegorz | Structural basis for tetrodotoxin-resistant sodium channel binding by μ-conotoxin SmIIIA | SmIIIA is a new μ-conotoxin isolated recently from Conus stercusmuscarum. Although it shares several biochemical characteristics with other μ-conotoxins (the arrangement of cysteine residues and a conserved arginine believed to interact with residues near the channel pore), it has several distin... | Conotoxins; Conotoxin SmIIIA; Tetrodotoxin | 2003 |
| 444 |
 |
Beckerle, Mary C. | Two muscle-specific LIM proteins in Drosophila | The LIM domain defines a zinc-binding motif found in a growing number of eukaryotic proteins that regulate cell growth and differentiation during development. Members of the cysteine-rich protein (CRP) family of LIM proteins have been implicated in muscle differentiation in vertebrates. Here we r... | LIM domains; Mlp60A; Mlp84B; Cysteine-rich proteins | 1996 |
| 445 |
 |
Jorgensen, Erik | Mutations in synaptojanin disrupt synaptic vesicle recycling | Synaptojanin is a polyphosphoinositide phosphatase that is found at synapses and binds to proteins implicated in endocytosis. For these reasons, it has been proposed that synaptojanin is involved in the recycling of synaptic vesicles. Here, we demonstrate that the unc-26 gene encodes the Caenorhab... | 2000 | |
| 446 |
 |
Sperry, John S. | Hydraulic consequences of vessel evolution in angiosperms | We tested two hypotheses for how vessel evolution in angiosperms influenced xylem function. First, the transition to vessels decreased resistance to flow--often considered the driving force for their evolution. Second, the transition to vessels compromised safety from cavitation--a constraint emergi... | Cavitation; Resistivity; Perforation | 2007 |
| 447 |
 |
Jorgensen, Erik | μ2 adaptin facilitates but is not essential for synaptic vesicle recycling in Caenorhabditis elegans | Synaptic vesicles must be recycled to sustain neurotransmission, in large part via clathrin-mediated endocytosis. Clathrin is recruited to endocytic sites on the plasma membrane by the AP2 adaptor complex. The medium subunit (u 2) of AP2 binds to cargo proteins and phosphatidylinositol-4,5-bisph... | Synaptic vesicles; Caenorhabditis elegans; Adaptin | 2008 |
| 448 |
 |
Beckerle, Mary C. | Microinjected fluorescent polystyrene beads exhibit saltatory motion in tissue culture cells | Microinjected 0.26-um fluorescent, carboxylated microspheres were found to display classical saltatory motion in tissue culture cells . The movement of a given particle was characterized by a discontinuous velocity distribution and was unaffected by the activity of adjacent particles. | Organelles; Microscopy; Proteins | 1984 |
| 449 |
 |
Jorgensen, Erik | Trio's Rho-specific GEF domain is the missing Gaq effector in C. elegans | The Gaq pathway is essential for animal life and is a central pathway for driving locomotion, egg laying, and growth in Caenorhcibditis elegans, where it exerts its effects through EGL-8 (phospholipase CB [PLCB]) and at least one other effector. To find the missing effector, we performed forward ... | 2007-11-01 | |
| 450 |
 |
Jorgensen, Erik | Mutations in β-spectrin disrupt axon outgrowth and sarcomere structure | B-Spectrin is a major component of the membrane skeleton, a structure found at the plasma membrane of most animal cells. B-Spectrin and the membrane skeleton have been proposed to stabilize cell membranes, generate cell polarity, or localize specific membrane proteins. We demonstrate that the Caen... | 2000 |