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TitleCreatorDescription
326 Systemic Disorders With Optic Nerve and Retinal FindingsLarry P. Frohman, MDSkin rashes occur in about 30 percent of patients with sarcoid. When seen, the rashes offer an accessible site for obtaining histologic material for confirmation of the clinical diagnosis. Pair with 91_68.
327 Neuro-Ophthalmic Imaging-MRIMitchell J. Wolin, MDAxial view of Arnold-Chiari malformation on a patient with downbeat nystagmus. Note the presence of the cerebellar tonsils posterior to the caudal medulla. In addition to downbeat nystagmus, Arnold-Chiari malformations can sometimes lead to increased intracranial pressure and papilledema.
328 Neuro-Ophthalmic Imaging-MRIMitchell J. Wolin, MDSagittal view of Arnold-Chiari malformation on a patient with downbeat nystagmus. The compression of the cervicomedullary junction is clearly depicted in the sagittal view.
329 Ocular Manifestations of Congenital/Inherited DiseasesWilliam Fletcher Hoyt, MDNeurofibromatosis, type 1, is an autosomal dominant phakomatosis characterized by Lisch nodules of the iris (hamartomas) plexiform neurofibromas, café-au-lait spots on the skin, and axillary freckling. Intracranial tumors such as optic pathway gliomas may occur. Disease/Diagnosis: Neurofibromatosis...
330 Ocular Manifestations of Congenital/Inherited DiseasesLarry P. Frohman, MDOn optic nerve CT scan, this patient with neurofibromatosis, type 1, shows the classic railroad-track sign of optic nerve meningioma and the kink sign of optic nerve glioma. Disease/Diagnosis: Neurofibromatosis, Type 1.
331 Isolated Optic Neuritis/NeuropathyJohn A. Charley, MDSeveral Primary Mutations result in Leber's hereditary optic neuropathy, including mitochondrial deletions at positions 11778, 3460, and 14484. Although the 11778 is the most common mutation, the 11484 has the best prognosis for spontaneous recovery. This case exhibits the 3460 mutation.
332 Isolated Optic Neuritis/NeuropathyJohn A. Charley, MDSeveral Primary Mutations result in Leber's hereditary optic neuropathy, including mitochondrial deletions at positions 11778, 3460, and 14484. Although the 11778 is the most common mutation, the 11484 has the best prognosis for spontaneous recovery. This case exhibits the 3460 mutation.
333 Isolated Optic Neuritis/NeuropathyJohn A. Charley, MDSeveral Primary Mutations result in Leber's hereditary optic neuropathy, including mitochondrial deletions at positions 11778, 3460, and 14484. Although the 11778 is the most common mutation, the 11484 has the best prognosis for spontaneous recovery. This case exhibits the 3460 mutation.
334 Isolated Optic Neuritis/NeuropathyJohn A. Charley, MDSeveral Primary Mutations result in Leber's hereditary optic neuropathy, including mitochondrial deletions at positions 11778, 3460, and 14484. Although the 11778 is the most common mutation, the 11484 has the best prognosis for spontaneous recovery. This case exhibits the 3460 mutation.
335 Isolated Optic Neuritis/NeuropathyJohn A. Charley, MDSeveral Primary Mutations result in Leber's hereditary optic neuropathy, including mitochondrial deletions at positions 11778, 3460, and 14484. Although the 11778 is the most common mutation, the 11484 has the best prognosis for spontaneous recovery. This case exhibits the 3460 mutation.
336 Isolated Congenital Optic Disc AnomaliesRoger Turbin, MDShown are the fundi of a - year old child with dominant optic atrophy, 20/200 OU. Pair with 1996_59. Disease/Diagnosis: Congenital optic atrophy.
337 Isolated Congenital Optic Disc AnomaliesRoger Turbin, MDShown are the fundi of a - year old child with dominant optic atrophy, 20/200 OU. Pair with 1996_60. Disease/Diagnosis: Congenital optic atrophy.
338 Neuro-Ophthalmic Vascular DiseaseMark L. Moster, MDNeovascularization of the iris may form in response to an ischemic disease of the retina, such as diabetic retinopathy. Carotid artery occlusion may result in ocular ischemia that may induce neovascularization.This is a dramatic image of iris neovascularization.
339 Neuro-Ophthalmic Imaging-CT ScanMitchell J. Wolin, MDThis is a patient with trauma leading to enucleation, with swelling years later over the implant. This is a presumed chronic abscess between orbit and dura.
340 Ocular Manifestations of Congenital/Inherited DiseasesWilliam Fletcher Hoyt, MDTuberous sclerosis is an autosomal dominant phakomatosis characterized by astrocytic hamartomas of the retina or optic nerve, adenoma sebaceum of the face, periungual fibromas, and astrocytic hamartomas of the brain, with secondary seizures and mental retardation. Disease/Diagnosis: Tuberous Scleros...
341 Ocular Manifestations of Congenital/Inherited DiseasesAnthony C. Arnold, MDNote the retinal/optic nerve head astrocytoma in a 12-year-old boy with tuberous sclerosis. Disease/Diagnosis: Tuberous Sclerosis.
342 Neuro-Ophthalmic Vascular DiseaseMark J. Kupersmith, MDAneurysms of the intracranial circulation may act as mass lesions and compress the afferent of efferent visual pathway. Ophthalmic artery aneurysms may compress the optic nerve and result in an optic neuropathy (ie, visual loss, afferent pupillary defect, optic atrophy). Treatment includes endovascu...
343 Systemic Disorders With Optic Nerve and Retinal FindingsMark J. Kupersmith, MDSarcoidosis is an inflammatory multisystem granulomatous disease that may result in an inflammatory or infiltrative optic neuropathy, papilledema from increased intracranial pressure due to meningeal inflammation or intracranial granuloma, or may present with an optic disc granuloma. Pair with 91_31...
344 Systemic Disorders With Optic Nerve and Retinal FindingsMark J. Kupersmith, MDSarcoidosis is an inflammatory multisystem granulomatous disease that may result in an inflammatory or infiltrative optic neuropathy, papilledema from increased intracranial pressure due to meningeal inflammation or intracranial granuloma, or may present with an optic disc granuloma. Pair with 91_32...
345 Systemic Disorders With Optic Nerve and Retinal FindingsLarry P. Frohman, MDSkin rashes occur in about 30 percent of patients with sarcoid. When seen, the rashes offer an accessible site for obtaining histologic material for confirmation of the clinical diagnosis. Pair with 91_69.
346 Trochlear Motility DisturbancesDon Bienfang, MDThis patient displays a posttraumatic left fourth nerve palsy sustained after having struck her head on the dashboard.
347 Motility DisturbancesThomas R. Wolf, MDThe patient is a 53-year-old man with diplopia from right oculomotor nerve palsy and left hemiparesis (Weber's syndrome), with associated left lung hilar mass. The spinal tap showed pleocytosis consistent with carcinomatous meningitis. This image demonstrates oculomotor nerve metastatic carcinomatos...
348 Ocular Manifestations of Congenital/Inherited DiseasesLarry P. Frohman, MDThis girl was 8 years old when these photographs were taken. She had been referred by pediatric neurology with ataxia. When seen, the findings of ataxia, poor convergence, early head thrusting maneuvers, and relatively preserved motility, in conjunction with the conjunctival findings as seen in the ...
349 Ocular Manifestations of Congenital/Inherited DiseasesLarry P. Frohman, MDThis girl was 8 years old when these photographs were taken. She had been referred by pediatric neurology with ataxia. When seen, the findings of ataxia, poor convergence, early head thrusting maneuvers, and relatively preserved motility, in conjunction with the conjunctival findings as seen in the ...
350 Systemic Disorders With Optic Nerve and Retinal FindingsLarry P. Frohman, MDThis is a 32-year-old HIV-positive man with anterior uveitis, vitritis, and bilateral papillitis from syphilis. With intravenous penicillin treatment, the optic discs and vision returned to normal.
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