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Creator | Title | Description | Subject | Date |
| 326 |
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Warner, Homer R. | The ILIAD Program: An Expert Computer Diagnostic Program | Biomedical Informatics | | 1992 |
| 327 |
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Caserta, Michael; Lund, Dale A. | Older bereaved spouses' participation in self-help groups | This study reports on bereaved spouses' assessments of their participation in twenty-six self-help groups which consisted of eight weekly meetings (short-term; N = 82) or ten monthly meetings in addition to the weekly ones (long-term; N = 52). Regardless of the duration of the groups whether they w... | Older bereaved spouses | 1992 |
| 328 |
 |
Florsheim, Paul W. | Mourning the loss of "self as father": a longitudinal study of fatherhood among the druze | IT is within the context of the parent-child relationship - through the processes of attachment, loss, separation and individuation - that we grow and develop interpersonally and intrapsychically (Bowlby 1969, 1980; Mahler et al. 1975; Pollock, 1989). Most developmentalists agree that changes in th... | | 1992 |
| 329 |
 |
Capecchi, Mario R. | Creating mice with targeted disruptions in protooncogenes and homeobox genes, NIH Director's Lecture given May 21, 1992 | This is an audio transcript of a 1 hour, 2 minutes and 12 seconds lecture given at the National Institutes of Health by Mario Capecchi on 1992/05/21. Beginning with a short summary of the mechanics of gene transfer and the ability to create germline chimera with mutations that become hereditary wit... | Transgenic mice; Gene targeting; Genetic engineering; Molecular genetics; Mutagenesis; Homeobox genes; Histology - Pathological; Gene expression; Gene regulation; Genotype; Phenotype | 1992 |
| 330 |
 |
Couldwell, William T. | Malignant glioma-derived soluble factors regulate proliferation of normal adult human astrocytes | Malignant gliomas are characteristically surrounded by marked gliosis. To assess whether glioma-derived products contribute to the proliferation of astrocytes, a feature of the gliosis response, we evaluated the influence of culture supernatants from malignant human glioma lines and tumor cyst fluid... | Astrocyte; Glioma; Gliosis; Proliferation; Soluble factors | 1992 |
| 331 |
 |
Caserta, Michael; Lund, Dale A. | Bereavement stress and coping among older adults: expectations versus the actual experience | This investigation compared the stress and coping levels of 108 older adults who recently lost their spouse with expectations of stress and coping reported by eighty-five matched nonbereaved controls. While the bereaved reported moderately high stress levels over two years, their stress scores were ... | Coping; Bereavement stress; Spousal bereavement | 1992 |
| 332 |
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Normann, Richard A.; Abbasi, Masoud; Johansson,Torbjorn | Silicon carbide enhanced thermomigration | The widespread acceptance of thermomigration technology to produce through-chip interconnects has been impaired by (i) a random walk of the Si-Al liquid eutectic inclusion as it traverses the wafer, and (ii) a ?surface barrier? which allows thermomigration of only relatively large inclusions. In ... | Silicon Dioxide; Thermometers; Transducers; Thermomigration Technology; Infrared Lamps | 1992 |
| 333 |
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Baehr, Wolfgang | Bilateral retinal and brain tumors in transgenic mice expressing simian virus 40 large T antigen under control of the human interphotoreceptor retinoid-binding protein promoter | We have previously shown that postnatal expression of the viral oncoprotein SV40 T antigen in rod photoreceptors (transgene MOT1), at a time when retinal cells have withdrawn from the mitotic cycle, leads to photoreceptor cell death (Al-Ubaidi et al., 1992. Proc. Natl. Acad. Sci. USA. 89:1194-1198).... | Simian virus 40; Retinol-Binding Proteins; Promoter Regions (Genetics) | 1992 |
| 334 |
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Gardner, Reed M. | Digital Electronic Communications Between ICU Ventilators and Computers and Printers | Biomedical Informatics | | 1992 |
| 335 |
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Baehr, Wolfgang | Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel | We have determined the primary structures of the human and mouse retinal rod cGMP-gated cation channel by analysis of cDNA clones and amplified DNA. The open reading frames predicted polypeptides of 690 and 683 residues exhibiting 88% sequence similarity. Sequence comparison indicated that the rod c... | Restriction Mapping; Sequence Homology, Nucleic Acid; Chromosomes, Human, Pair 4 | 1992 |
| 336 |
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Baehr, Wolfgang | In vitro isoprenylation and membrane association of mouse rod photoreceptor cGMP phosphodiesterase alpha and beta subunits expressed in bacteria | We investigated the specificity of CAAX box-related isoprenylation of rod photoreceptor cGMP phosphodiesterase (PDE) subunits expressed in bacteria and the consequences of this modification on rod disk membrane association. Full-length cDNA sequences of the alpha and beta subunits of mouse PDE, inse... | Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Molecular Sequence Data | 1992 |
| 337 |
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Normann, Richard A.; Horch, Kenneth W.; Cha, Kichul | Mobility performance with a pixelized vision system | A visual prosthesis, based on electrical stimulation of the visual cortex, has been suggested as a means for partially restoring functional vision in the blind. The prosthesis would create a pixelized visual sense consisting of punctate spots of light (phosphenes). The present study investigated the... | Visual Prosthesis; Mobility; Phosphene Simulator | 1992 |
| 338 |
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Digre, Kathleen B. | Selective MR imaging approach for evaluation of patients with Horner's syndrome. | PURPOSE: To assess the usefulness of MR in the evaluation of patients with Horner's syndrome. PATIENTS AND METHODS: We prospectively performed MR imaging in 33 patients with Horner's syndrome (13 preganglionic and 20 postganglionic) using a protocol specifically designed for pre- and postganglionic ... | Horner Syndrome; Magnetic Resonance Imaging; Epidemiology | 1992-01 |
| 339 |
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Mitchell, Joyce A. | Preliminary evaluation of learning via the AI/LEARN/Rheumatology interactive videodisc system | AI/LEARN/Rheumatology is a level three videodisc system to teach clinical observational skills in three important diseases: rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. The AI/LEARN software was developed on an independent authoring system called GALE designed for MS-DOS based c... | | 1992-01-01 |
| 340 |
 |
Mitchell, Joyce A. | The columbia registry of controlled clinical computer trials | Numerous reports on randomized controlled clinical trials of comnputer-based interventions have been published. These trials provide useful evaluations of the impact of information technology on patient care. Unfortunately, several obstacles make access to the trial reports difficult. Barriers inclu... | | 1992-01-01 |
| 341 |
 |
Digre, Kathleen B.; Mamalis, Nick; White, George L. Jr. | Congenital anomalies of the optic nerve in one family. | We present three cases of congenital optic disc anomalies in one family who underwent an extensive diagnostic workup to exclude any intracranial pathology. One patient had elevated optic nerve heads and was hospitalized for multiple diagnostic tests including a lumbar puncture and magnetic resonance... | Optic Nerve; Congenital Anomalies | 1992-04-24 |
| 342 |
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| KSL News clip of Mario Capecchi receiving the National Medal of Science for 1991 | This 1 minute, 44 seconds news clip from Salt Lake City's KSLTV, Channel 5 shows Mario Capecchi receiving the National Medal of Science for 1991 from President George W. Bush at the June 13, 2002 awards ceremony. The medal was presented for Capecchi's work in genetics and his development of the pro... | Transgenic mice; Gene targeting; Capecchi, Mario R.; Science - Awards - United States; Television broadcasting of news | 1992-06 |
| 343 |
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Digre, Kathleen B.; Skuster, Denise Z. | Neurologic conditions presenting as psychiatric disorders. | Understanding underlying neuroanatomic function helps physicians to localize defects and search for treatable neurologic conditions. Neurologic conditions such as Huntington's chorea, Wilson's disease, Gille de la Tourette syndrome, brain tumors, encephalitis and meningitis, neurodegenerative condit... | Psychiatric Diagnosis; Neurologic Disease | 1992-06-15 |
| 344 |
 |
Thomas, Kirk R.; Capecchi, Mario R. | High-fidelity gene targeting in embryonic stem cells by using sequence replacement vectors. | Mutations were targeted to the Hprt locus in murine embryonic stem cells by using sequence replacement vectors. When the vector was designed such that the mutated sequences were flanked on both sides by several kilobases of DNA homologous to the target locus, replacement of chromosomal sequences wit... | Drug Resistance; Gene Rearrangement; Gentamicins | 1992-07 |
| 345 |
 |
Battin, Margaret P. | To die or not to die? (Book Review) | Reviews the book `To Die or Not to Die? Cross-disciplinary, Cultural, and Legal Perspectives on the Right to Choose Death,' edited by Arthur S. Berger and Joyce Berger. | Books; Law; Death | 1992-07 |
| 346 |
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Capecchi, Mario R. | Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. | Mutations were targeted to the Hprt locus of mouse embryo-derived stem cells by using 22 different sequence replacement and sequence insertion vectors. The targeting frequency was examined at two sites within the Hprt locus as a function of the extent of homology between the targeting vector and the... | Cell Line; DNA Transposable Elements; Embryo; Exons; Mice | 1992-08-12 |
| 347 |
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Warner, Homer R. | A View of Medical Informatics as an Academic Disipline (Editorial) | Biomedical Informatics | | 1993 |
| 348 |
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Warner, Homer R. | Student Paper Finalists: SCAMC 1992 (Editorial) | Biomedical Informatics | | 1993 |
| 349 |
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Warner, Homer R. | Stepping Down as Editor of Computers and Biomedical Research (Editorial) | Biomedical Informatics | | 1993 |
| 350 |
 |
Couldwell, William T. | Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifen | PREVIOUS WORK HAS demonstrated the importance of the Protein Kinase C (PKC) signal transduction system in regulating the growth rate of malignant gliomas in vitro. Tamoxifen inhibits PKC in a minority of malignant gliomas within the micromolar concentration range in vitro, a property distinct from... | Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Chemotherapy; Glioma | 1993 |
