|
|
Creator | Title | Description | Subject | Date |
| 276 |
 |
Normann, Richard A.; Jones, Kelly E. | Advanced demultiplexing system for physiological stimulation | A CMOS very large scale integration (VLSI) chip has been designed and built to implement a scheme developed for multiplexing/demultiplexing the signals required to operate an intracortical stimulating electrode array. Because the use of radio telemetry in a proposed system utilizing this chip may im... | Electrode Array; Stimulation; Telemetry; Microelectrodes; Transistors | 1997 |
| 277 |
 |
Rogers, Alan R.; Jorde, Lynn B. | Origins and affinities of modern humans: a comparison of mitochondrial and nuclear genetic data | To test hypotheses about the origin of modern humans, we analyzed mtDNA sequences, 30 nuclear restriction-site polymorphisms (RSPs), and 30 tetranucleotide short tandem repeat (STR) polymorphisms in 243 Africans, Asians, and Europeans. An evolutionary tree based on mtDNA displays deep African branch... | Base Sequence; Variation (Genetics); Base Sequence | 1995 |
| 278 |
 |
Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 16: bone graft extenders and substitutes | Standards. The use of autologous bone or rhBMP-2 bone graft substitute is recommended in the setting of an ALIF in conjunction with a threaded titanium cage. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) Recombinant human BMP-2 in combination with HA ... | Lumbar fusion; Lumbar spine; Bone graft; Treatment outcome; Practice guidelines; Degenerative disease | 2005 |
| 279 |
 |
Florsheim, Paul W.; Ngu, Le | Differential outcomes among adolescent fathers: understanding fatherhood as a transformative process | In response to the rising numbers of mother headed households, there is a great debate about whether to encourage young unwed parents to marry. Policies designed to pursue and/or punish fathers who do not meet their legal and financial responsibilities and to promote marriage, carte blanche, are ref... | Parenting; Gender; Matrimony | 2003-10-18 |
| 280 |
 |
Caserta, Michael; Lund, Dale A. | When the unexpected happens: husbands coping with the deaths of their wives | Most husbands do not outlive their wives. The 1990 Census of the United States reveals that while nearly 49 percent of women are widowed after age sixty-five only 14 percent of the men are widowed. After age eighty-five the rates of widowhood increase for both men and women. About 80 percent of thes... | | 2001 |
| 281 |
 |
Caserta, Michael; Lund, Dale A. | Sleep patterns in older bereaved spouses | The study examined the prevalence and pattern of reports of sleep disturbance over two years in a group of 296 adults aged 50 years and over, and assessed the relationship between patterns of sleep disturbance and bereavement adjustment over time. A sample of 192 widows and widowers were compared t... | Bereavement adjustment; Older bereaved spouses; Sleep patterns; Sleep disturbance | 2003-11-01 |
| 282 |
 |
Creel, Donnell J.; Leventhal, Audie G. | Retinal projections in tyrosinase-negative albino cats | Retinal projections were examined in two tyrosinase-negative albino cats using autoradiographic techniques. Cats from this colony have pink eyes; their retinal pigment epithelium, ciliary body, and iris epithelium are completely devoid of melanin pigment. Test breeding for five generations indicates... | Cats; Albinism; Vision; Autoradiography; Retina | 1982-07 |
| 283 |
 |
Couldwell, William T. | Comment on Kitano, M., et al.: Subdural patch graft technique for watertight closure of large dural defects in extended transsphenoidal surgery | Ahn and Kim demonstrate a suturing technique to close dural defects after transsphenoidal and extended transsphenoidal approaches. The technique entails a specifically designed forceps to cinch the knot down in the depths of the field. The Author's used the technique in 21 consecutive patients (16 e... | Transsphenoidal surgery; CSF leaks | 2009 |
| 284 |
 |
Hymas, Weston C.; Hillyard, David R. | Novel one step real time RT-PCR assay for the detection of Enterovirus, A | This poster describes the development of a novel real time assay that utilizes primers and an Eclipse probe in an overlapping format upstream of the Rotbart amplicon. | RT-PCR Assay | 2005-11-08 |
| 285 |
 |
Kestle, John R. W. | Comparison between magnetic resonance imaging and computed tomography for stereotactic coordinate determination | The spatial accuracy of magnetic resonance imaging (MRI) has not been established for stereotactic surgery. Magnetic susceptibility artifacts may lead to anatomical distortion and inaccurate stereotactic MRI coordinates, especially when targets are in regions of the brain out of the center of the ma... | Computed tomography; Stereotactic coordinates; Stereotactic surgery | 1992 |
| 286 |
 |
Zhang, Kang; Yang, Zhenglin; Jiang, Li | Mutations in LRP5 or FZD4 underlie the common familial exudative vitreoretinopathy locus on chromosome 11q | Familial exudative vitreoretinopathy (FEVR) is an inherited blinding disorder of the retinal vascular system. Autosomal dominant FEVR is genetically heterogeneous, but its principal locus, EVR1, is on chromosome 11q13-q23. The gene encoding the Wnt receptor frizzled-4 (FZD4) was recently reported ... | Familial exudative vitreoretinopathy; FEVR; Inherited blinding disorders | 2004 |
| 287 |
 |
Capecchi, Mario R. | Developmental defects of the ear, cranial nerves and hindbrain resulting from targeted disruption of the mouse homeobox gene Hox-1.6. | Gene targeting in mouse embryo-derived stem cells has been used to generate mice with a disruption in the homeobox gene Hox-1.6. Mice heterozygous at the Hox-1.6 locus appear normal, whereas Hox-1.6-/Hox-1.6- mice die at or shortly after birth. These homozygotes exhibit profound defects in the forma... | Chromosome Mapping; Genetic Vectors; Mice, Inbred C57BL | 2002-06-27 |
| 288 |
 |
Kestle, John R. W.; Walker, Marion L. | Noncommunicating spinal extradural arachnoid cyst causing spinal cord compression in a child | Extradural arachnoid cysts in the spine are relatively uncommon causes of spinal cord compression in the pediatric population that are thought to arise from congenital defects in the dura mater. Most reports describe such cysts communicating with the intrathecal subarachnoid space through a small de... | | 2006 |
| 289 |
 |
Baehr, Wolfgang; Zhang, Kang; Kolb, Helga | Gene array and expression of mouse retina guanylate cyclase activating proteins 1 and 2 | PURPOSE: To identify gene arrangement, chromosomal localization, and expression pattern of mouse guanylate cyclase activating proteins GCAP1 and GCAP2, retina-specific Ca2+-binding proteins, and photoreceptor guanylate cyclase activators. METHODS: The GCAP1 and GCAP2 genes were cloned from genomic l... | Molecular Sequence Data; Guanylate Cyclase-Activating Proteins; In Situ Hybridization, Fluorescence | 1998 |
| 290 |
 |
Capecchi, Mario R. | Regionally restricted developmental defects resulting from targeted disruption of the mouse homeobox gene hox-1.5. | Gene targeting in mouse embryo-derived stem cells has been used to disrupt the homeobox gene hox-1.5. Mice heterozygous at the hox-1.5 locus appear normal, whereas hox-1.5-/hox-1.5- mice die at or shortly after birth. These homozygotes are athymic, aparathyroid, have reduced thyroid and submaxillary... | Abnormalities, Multiple; Animals, Newborn; Arteries; Bone and Bones; Cartilage; Esophagus; Gene Expression; Heart Defects, Congenital; Organ Specificity; Parathyroid Glands; Pharynx; Thymus Gland; Thyroid Gland; Trachea | 1991-04-11 |
| 291 |
 |
Normann, Richard A.; Kolb, Helga; Lasater, Eric M. | Signal integration at the pedicle of turtle cone photoreceptors: an anatomical and electrophysiological study | The morphology of the axon which connects the cell body and pedicle of turtle cone photoreceptors was studied by light and electron microscopy. The axon which contains numerous synaptic vesicles, some endoplasmic reticulum, and a few cisternae is basically filled with cytoplasm. The length of the ax... | Cone Photoreceptor, Voltage Clamp; Isolated Cells; Input Resistance; Cell Body-Pedicle Coupling | 1989 |
| 292 |
 |
Baehr, Wolfgang | Calcium-sensitive particulate guanylyl cyclase as a modulator of cAMP in olfactory receptor neurons | The second messengers cAMP and inositol-1,4,5-triphosphate have been implicated in olfaction in various species. The odorant-induced cGMP response was investigated using cilia preparations and olfactory primary cultures. Odorants cause a delayed and sustained elevation of cGMP. A component of this c... | Calcium-Binding Proteins; Nerve Tissue Proteins; Rats, Sprague-Dawley | 1998 |
| 293 |
 |
Blumenthal, Donald K. | Identification of the calmodulin-binding domain of skeletal muscle myosin light | In the course of determining the primary structure of rabbit skeletal muscle myosin light chain kinase (MLCK; ATP:protein phosphotransferase, EC 2.7.1.37) a peptide fragment was obtained that appears to represent the calmodulin-binding domain of this enzyme. Low concentrations of the peptide inhibit... | Peptides; Enzymes; Protein sequence | 1985-05 |
| 294 |
 |
Dailey, Andrew T. | Diagnosis and treatment of craniocervical dislocation in a series of 17 consecutive survivors during an 8-year period | Object. Craniocervical dissociation (CCD) is a highly unstable and usually fatal injury resulting from osseoligamentous disruption between the occiput and C-2. The purpose of this study was to elucidate systematic factors associated with delays in diagnosing and treating this life-threatening condit... | Spinal cord injury; Craniocervical dislocation; Atlantooccipital joint; Atlantoaxial joint; Tetraplegia; CCJ; CCD | 2006 |
| 295 |
 |
Varner, Michael W. | Association of obesity with pulmonary and nonpulmonary complications of pregnancy in asthmatic women. | OBJECTIVE: To evaluate whether maternal obesity is associated with pulmonary and nonpulmonary pregnancy complications in asthmatic women. METHODS: This is a secondary analysis of the prospective cohort Asthma During Pregnancy Study. Asthma patients were classified as having either mild or moderate t... | Asthma; Body Mass Index; Pregnancy Outcome; Lung Diseases | 2006-07 |
| 296 |
 |
Capecchi, Mario R. | Measurement of suppressor transfer RNA activity. | Transfer RNA (tRNA) suppression of nonsense mutations in prokaryotic systems has been widely used to study the structure and function of different prokaryotic genes. Through genetic engineering techniques, it is now possible to introduce suppressor (Su+) tRNA molecules into mammalian cells. A quanti... | Animals; Cells, Cultured; Eukaryotic Cells; Genes, Viral; Mice; Orthomyxoviridae; Peptide Chain Termination, Translational; Protein Biosynthesis | 1983-08-26 |
| 297 |
 |
Schmidt, Meic H. | Photodynamic therapy | We appreciate the comments of Drs. Kaye and Hill on our article. We are pleased that these investigators concurred with our impression that photodynamic therapy (PDT) may potentially be useful in the treatment of posterior fossa tumors. Several interesting questions were raised about the technical ... | Photodynamic therapy; Photofrin | 1994 |
| 298 |
 |
Couldwell, William T. | Personal perspective: AANS Bulletin's momentum continues: new editor considers peer review, practice survey impact | With this issue, I assume the reins as editor of the AANS Bulletin. I am indebted to James Bean, MD, for his extraordinary efforts in this capacity, as witnessed by review of the recent issues published under his leadership. An important initiative put forth by Dr. Bean and the Bulletin Advisory Boa... | | 2005 |
| 299 |
 |
Couldwell, William T. | Medical and surgical management of microprolactinoma | A recent report by Colao et al. [1] indicates that a significant proportion of patients harboring prolactinomas treated with cabergoline will have persistence of remission of hyperprolactinemia following withdrawal of the drug. The prolactin and tumor control rates in the study suggest that medical ... | Microprolactinoma; Prolactinoma; Cabergolene | 2004 |
| 300 |
 |
Hansen, Mark S.; Coffin, Cheryl M.; Capecchi, Mario R. | Pax3:Fkhr interferes with embryonic Pax3 and Pax7 function: implications for alveolar rhabdomyosarcoma cell of origin. | To investigate the role of the translocation-associated gene Pax3:Fkhr in alveolar rhabdomyosarcomas, we generated a Cre-mediated conditional knock-in of Pax3:Fkhr into the mouse Pax3 locus. Exploring embryonic tumor cell origins, we replaced a Pax3 allele with Pax3:Fkhr throughout its expression do... | Neuroprogenitor; Embryogenesis | 2004-11-01 |
