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CreatorTitleDescriptionSubjectDate
251 Couldwell, William T.Diagnosis and management of Cushing diseaseThe management of a case involving Cushing disease, defined as excess secretion of adrenocorticotropic hormone (ACTH) from a pituitary adenoma, remains one of the most vexing problems facing the pituitary surgeon. The systemic consequences of this endocrinopathy are profound morbidity and premature...2007-01-01
252 Couldwell, William T.; Nelson, Don HarryNelson syndrome: historical perspectives and current conceptsThe appearance of an adrenocorticotropic hormone (ACTH)-producing tumor after bilateral adrenalectomy for Cushing disease was first described by Nelson in 1958. The syndrome that now bears his name was characterized by hyperpigmentation, a sellar mass, and increased plasma ACTH levels. The treatment...2007-01-01
253 Schmidt, Meic H.Thoracoscopic vertebral body replacement with an expandable cage after ventral spinal canal decompressionOBJECTIVE: Minimally invasive thoracic anterior surgery using a thoracoscopic approach has evolved to include spinal biopsy, debridement, discectomy, decompressive corpectomy, interbody fusions, and internal fixations. Minimal access techniques can potentially decrease surgical access morbidity and...2007-01-01
254 Digre, Kathleen B.Serum vitamin A concentration is elevated in idiopathic intracranial hypertension.OBJECTIVE: The primary purpose was to investigate whether serum vitamin A concentration is associated with idiopathic intracranial hypertension (IIH). The secondary aim was to obtain pilot data regarding the amount of vitamin A ingested by patients and controls. BACKGROUND: Vitamin A is an attractiv...Vitamin A; Retinol; Idiopathic intracranial hypertension; Chromatography2007-02-01
255 Couldwell, William T.; Chin, Steven S.Extranodal NK/T-cell lymphoma presenting as a pituitary massExtranodal NK/T-cell lymphomas are uncommon neoplasms that are highly aggressive and show a strong association with Epstein-Barr virus. They most commonly affect the nasal cavity and paranasal sinuses; manifestation as a primary pituitary tumor has never been described. The authors report a case of ...2007-09
256 Couldwell, William T.Radiographic features of tumefactive giant cavernous angiomasGiant cavernous angiomas (GCAs) are very rare, and imaging features of GCAs can be very different from those of typical cavernous angiomas (CAs), making them a diagnostic challenge. The purpose of the study was to evaluate the radiographic features of GCAs, with an emphasis on the differentiating fe...Cavernous angiomas; Cavernous malformations; Tumefactive2008
257 Schmidt, Meic H.Minimally invasive thoracoscopic approach for anterior decompression and stabilization of metastatic spine diseaseObject. The choices available in the management of metastatic spine disease are complex, and the role of surgical therapy is increasing. Recent studies have indicated that patients treated with direct surgical decompression and stabilization before radiation have better functional outcomes than thos...Metastatic spine disease; Minimally invasive surgery; Spinal cord decompression2008
258 Couldwell, William T.; Osborne, Anne G.Hypertrophic olivary degeneration after surgical removal of cavernous malformations of the brain stem: report of four cases and review of the literatureBackground: Hypertrophic olivary degeneration (HOD) is a pathological phenomenon that occurs after injury to the dentato-olivary pathway. Its hallmarks include hypertrophy of the olive with increased T2 signal intensity on magnetic resonance imaging, and often manifests with palatal tremor and osci...Hypertrophic olivary degeneration; Surgery; Cavernous malformation; Brainstem2008
259 Couldwell, William T.; Gillespie, David L.; Jensen, Randy L.Comparison of the cell lines used in meningoma researchBackground: Immortal cell lines and cell lines derived from operative specimens transplanted into animal models are used in meningioma research. We address two criticisms of the mouse xenograft flank tumor model: Why are tumor induction rates derived from operative specimens low and inconsistent? Ar...CH-157 MN; IOMM-Lee; Meningioma; Xenograft Mouse Model; Flank tumors2008
260 Couldwell, William T.; Yonemura, Kenneth S.Use of the Olympus endoArm for spinal and skull-based transsphenoidal neurosurgeryMinimally invasive surgical techniques have evolved to reduce soft-tissue injury associated with open surgical techniques. The use of endoscopic visualization allows the exposure of deep structures and provides a mechanism to perform all the components of an open surgical procedure through small p...EndoArm; Endoscope; Pneumatic; Skull-based; Transsphenoidal neurosurgery2008
261 Dailey, Andrew T.Variations in surgical treatment of cervical facet dislocationsObjective. To explore surgeon preference in the choice of surgical approach in the treatment of traumatic cervical facet dislocations. Summary of Background Data. The choice of surgical approach in the treatment of traumatic cervical dislocations is highly variable and maybe influenced by a vari...Cervical facet dislocations; Spine Trauma Study Group2008
262 Dailey, Andrew T.; Brodke, Darrel S.Cervical end of an occipitocervical fusion: a biomechanical evaluation of 3 constructsObject. Stabilization with rigid screw/rod fixation is the treatment of choice for craniocervical disorders requiring operative stabilization. The authors compare the relative immediate stiffness for occipital plate fixation in concordance with transarticular screw fixation (TASF), C-1 lateral mass...Harms technique; Occipitocervical fusion; Transarticular screw; Translaminar screw; Craniocervical instability2008
263 Kestle, John R. W.It's randomized and double blinded... what more do we want?This issue of Journal of Neurosurgery: Pediatrics presents a randomized trial in which investigators have evaluated antimicrobial suture (AMS) in the prevention of shunt infection. The authors randomized 84 shunt procedures in 61 patients over 21 months. The surgeons and patients were blinded to...2008
264 Dailey, Andrew T.Vertebral artery injuries associated with cervical spine injuries: a review of the literatureObjective: To determine the incidence of vertebral artery injuries (VAIs) in association with cervical spine trauma and investigate the optimum diagnostic and treatment protocols. Summary of Background Data: VAIs may result from cervical spine trauma and have the potential to cause cerebral, brain...Cervical spine injuries; Literature review2008
265 Couldwell, William T.; Apfelbaum, Ronald I.Transoral approach and extended modifications for lesions of the ventral foramen magnum and craniovertebral junctionObjectives: To describe our method of performing the transoral approach and the extended approaches to the ventral foramen magnum and craniovertebral junction and review the technical aspects and operative nuances. Design: Review Results: The transoral approach provides direct midline exposure to a...Craniovertebral junction; Foramen magnum; Skull base surgery; Transoral approach2008
266 Dailey, Andrew T.Surgical treatment of occipitocervical instabilityOBJECTIVE: Instability of the occipitocervical junction can be a challenging surgical problem because of the unique anatomic and biomechanical characteristics of this region. We review the causes of instability and the development of surgical techniques to stabilize the occipitocervical junction. ...Occipitocervical instability2008
267 Dailey, Andrew T.Subaxial cervical spine trauma classification: the subaxial injury classification system and case examplesObject. The authors review a novel subaxial cervical trauma classification system and demonstrate its application through a series of cervical trauma cases. Methods. The Spine Trauma Study Group collaborated to create the Subaxial Injury Classification (SLIC) and Severity score. The SLIC system is...Cervical spine trauma; Injury severity score; Spinal cord injury; Subaxial Injury Classification; SLIC; Discoligamentous integrity; Neurological status2008
268 Dailey, Andrew T.; Brodke, Darrel S.Differences between neurosurgeons and orthopaedic surgeons in classifying cervical dislocation injuries and making assessment and treatment decisions: a multicenter reliability studyVariability exists in the management of cervical spinal injuries. The goal of this study was to assess the effect of training specialty (orthopedic surgery vs neurosurgery) on management of cervical dislocations.Cervical dislocation injuries; Classification; Orthopedic surgeons; Orthopaedic surgeons; Assessment decisions; Treatment decisions2008
269 Couldwell, William T.Medpor implant in cranioorbitomaxillary reconstruction: institutional experience and a review of the literatureAutologous materials remain the gold standard for complex skull base and craniofacial reconstruction, but they carry additional morbidity associated with the second harvest procedure and with prolonged operation time. These autologous materials also resorb in a way that is not predictable, rendering...Medpor; Alloplastic material; Autogenous tissue; Craniofacial reconstruction; Skull base surgery; Methylmethacrylate; Silicone2008
270 Couldwell, William T.; Schmidt, Richard H.Ruptured intracranial dermoid cysts: clinical, radiographic, and surgical featuresIntracranial dermoid cysts are pathologically characterized by a thick, stratified squamous epithelium cyst wall containing dermal elements. Rupture into the subarachnoid spaces and ventricles is extremely rare. We review the clinical, radiographic, and surgical features of eight ruptured dermoid c...Dermoid cyst; Intracranial; Rupture; Tumor2008
271 Schmidt, Meic H.Management of brain abscesses associated with halo fixationHalo orthoses are commonly used in the management of a variety of cervical spinal pathological conditions. Although placement of the cranial pins was initially believed to be safe with minimal complications, minor complications related to the cranial pins have the potential to create a setting for ...Cerebral abscess; Cranial pin; Halo orthosis; Halo fixation; Inner table of skull2008
272 Kestle, John R. W.Ventriculoperitoneal shunts in children: indications, equipment and techniquesThe decision to implant a ventriculoperitoneal shunt in a child with ventriculomegaly should not be taken lightly. Once a shunt has been implanted, it is very difficult to determine that it is no longer necessary, and therefore the initial decision is very important. Sometimes the need is obvious, s...2008
273 Couldwell, William T.Choroid plexus cyst development and growth following ventricular shuntingChoroid plexus cysts are typically incidental, asymptomatic cysts. They have been reported to hemorrhage and grow, causing symptoms of obstruction. However, growth and multiplication has not been reported following ventriculoperitoneal shunting procedures. A 66-year-old woman initially underwent a ...Choroid plexus cyst; Ventriculoperitoneal shunt2008-01
274 Couldwell, William T.Practicing neurosurgery in the United StatesCompared with other developed countries, the U.S. spends a high percentage of its gross domestic product on healthcare: 16 percent in 2005, up from 15 percent in 2004. This is far and away the greatest percentage of GDP spent on healthcare of any nation for which such data is collected. However,...2008-01-01
275 Couldwell, William T.Stress and burnout: insidious influencesA career in neurosurgery may take a substantial toll on an individual?s body and mind. From the ?baptism by fire? experienced by a brand-new junior resident, to keeping one?s head above water as the residency proceeds, to the realization shortly after graduation of being responsible for the health a...2008-01-01
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