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Creator | Title | Description | Subject | Date |
| 251 |
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Couldwell, William T. | Pallidotomy in advanced Parkinson's disease | To the Editor: We read with interest the comments published regarding our recent article on pallidotomy in patients with advanced Parkinson's disease (3). There seems to be confusion as to some of the technical methods used in creating the radiofrequency lesions in these patients. As noted in the Pa... | Pallidotomy; Dyskinesia | 1995 |
| 252 |
 |
Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A. | Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis. | A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-assoc... | Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex | 2006-07-11 |
| 253 |
 |
Couldwell, William T. | Increased invasive capacity of connexin43-overexpressing malignant glioma cells | Object. Malignant glioma cells, similar to astrocytes, express connexin43 (Cx43) universally but at widely varied levels. Data from previous studies have demonstrated that malignant glioma cells form functional gap junction channels among themselves as well as with astrocytes and that such a communi... | | 2003-12 |
| 254 |
 |
Couldwell, William T. | Protein kinase C and growth regulation in malignant gliomas | To the Editor: The presence of amplified growth factor systems in many tumor models, including malignant gliomas, raises the question of how such external signals are transduced into a transformed phenotype (increased proliferation, invasion, lack of contact inhibition, angiogenic capacity, etc.). ... | Protein kinase C; Glioma; Brain neoplasm; protooncogenes; Apoptosis; Tamoxifen | 1994 |
| 255 |
 |
Couldwell, William T. | No ordinary time, no ordinary men: the relationship between Harvey Cushing and Franklin D. Roosevelt, 1928-1939 | The authors elucidate the strong personal relationship that developed between Dr. Harvey Cushing and Franklin Delano Roosevelt (FDR) from 1928 to 1939, as manifested in their frequent letters to each other. The relationship was initiated by the marriage of their children. Through his correspondence ... | | 2001 |
| 256 |
 |
Schmidt, Meic H. | NASA light-emitting diode medical program-progress in space flight and terrestrial applications | This work is supported and managed through the NASA Marshall Space Flight Center - SBIR Program. Studies on cells exposed to microgravity and hypergravity indicate that human cells need gravity to stimulate cell growth. As the gravitational force increases or decreases, the cell function responds in... | Terrestrial applications; Cell growth; NASA; Microgravity environment | 2000 |
| 257 |
 |
Couldwell, William T. | Distal ventriculoperitoneal shunt failure secondary to Clostridium Difficile Colitis | Distal ventriculoperitoneal shunt obstruction is typically associated with cerebrospinal fluid (CSF) infection, fluid pseudocysts, bowel obstruction, bowel perforation, or improper shunt placement in the abdomen. We describe a unique etiology for distal shunt obstruction secondary to Clostridium dif... | Shunt Failure | 2005-03 |
| 258 |
 |
Couldwell, William T. | Medpor implant in cranioorbitomaxillary reconstruction: institutional experience and a review of the literature | Autologous materials remain the gold standard for complex skull base and craniofacial reconstruction, but they carry additional morbidity associated with the second harvest procedure and with prolonged operation time. These autologous materials also resorb in a way that is not predictable, rendering... | Medpor; Alloplastic material; Autogenous tissue; Craniofacial reconstruction; Skull base surgery; Methylmethacrylate; Silicone | 2008 |
| 259 |
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Schmidt, Meic H. | Diagnosis and management of sacral Tarlov cysts | Perineurial (Tarlov) cysts are meningeal dilations of the posterior spinal nerve root sheath that most often affect sacral roots and can cause a progressive painful radiculopathy. Tarlov cysts are most commonly diagnosed by lumbosacral magnetic resonance imaging and can often be demonstrated by com... | Tarlov cysts; Meningeal dilations; Spinal lesion; Outcome | 2003 |
| 260 |
 |
Couldwell, William T. | Unruptured posterior communicating artery aneurysm presenting with gustatory seizures and temporal lobe edema | Unruptured cerebral aneurysms presenting with seizures are unusual. We describe a case of a growing middle cerebral artery aneurysm presenting with gustatory seizures with magnetic resonance imaging showing peri-aneurysmal edema. This case is the first to show temporal lobe edema associated with inc... | Seizure; Brain edema; PCOM | 2009-04 |
| 261 |
 |
Dailey, Andrew T.; Brodke, Darrel S. | Utility of helical computed tomography in differentiating unilateraland bilateral facet dislocations | Objective: Diagnosis of cervical facet dislocation is difficult when relying on plain radiographs alone. This study evaluates the interobserver reliability of helical computed tomography (CT) in the assessment of cervical translational injuries, correlates the radiographic diagnosis with intraoper... | Facet dislocations; Helical computed tomography; Spinal trauma | 2009 |
| 262 |
 |
Couldwell, William T. | Cranioplasty with the Medpor porous polyethylene Flexblock implant | The authors describe the use of a porous polyethylene Flexblock implant for cosmetic cranioplasty. The implant may be used to cover any small- or medium-sized (< 8 cm) cranial defect, offering similar cosmetic results to standard alloplast cranioplasty while decreasing operation time. The porous i... | Cranioplasty; Medpor; Alloplast; Polyethylene; Skull defect | 1994 |
| 263 |
 |
Couldwell, William T. | Cholesteatoma of the clivus case report | Objective: Cholesteatomas (CNS epidermoids) can be found intradurally or extradurally in the central nervous system. Extradural intraosseous lesions are most commonly found in the petrous bone. Design: Case report Clinical Presentation: The authors describe a unique case of a clival cholesteatoma o... | | 2006-01-01 |
| 264 |
 |
Kestle, John R. W. | Natural history of cerebral cavernous malformations | To determine the natural history of brain cavernous malformations, the authors entered patients referred to their center into a prospective registry between 1987 and 1993. All patients underwent magnetic resonance imaging, which showed the typical appearance of this lesion, and conservative manageme... | Cavernous malformation; Vascular malformation; Seizure | 1995 |
| 265 |
 |
Swallow, Charles E.; Tsuruda, Jay S.; Digre, Kathleen B.; Glaser, Matthew J.; Davidson, H. Christian; Harnsberger, H. Ric | Terson syndrome: CT evaluation in 12 patients. | PURPOSE: Terson syndrome may be overlooked in the acute setting and often requires ophthalmologic intervention to prevent long-term visual loss. In this syndrome, vitreous or retinal hemorrhage results from an abrupt rise in intracranial pressure, leading to retinal venous hypertension and intraocul... | Retinal Hemorrhage; Visual Acuity; Vitreous Hemorrhage | 1998-04 |
| 266 |
 |
Kestle, John R. W. | Shunt insertion in the summer: is it safe? | Object. The potential for increased complications related to the arrival of new residents in July each year has not previously been demonstrated in the neurosurgical literature. The authors investigated this phenomenon in children undergoing cerebrospinal fluid shunt surgery. Methods. Data were ob... | Ventriculoperitoneal shunt; July effect; Complication; Shunt insertion | 2006 |
| 267 |
 |
Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 12: pedicle screw fixation as an adjunct to posterolateral fusion for low-back pain | Standard. There is insufficient evidence to recommend a treatment standard. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. 1) Pedicle screw fixation is recommended as a treatment option for patients with low-back pain treated with PLF who are at high risk... | Fusion procedures; Degenerative disease; Lumbar spine; Pedicle screw fixation; Posterolateral fusion; Low-back pain | 2005 |
| 268 |
 |
Kestle, John R. W.; Brockmeyer, Douglas Lee | Evaluation of the necessity of postoperative imaging after craniosynostosis surgery | Object. Childhood radiation exposure increases the lifetime risk of cancer from an estimated 0.07 to 0.35%. Neurological evaluation of patients after cranial vault reconstruction for synostosis repair is often complicated by pain medication, sedation, intubation, swelling, and dressings; therefore c... | Computed tomography; Cranial vault reconstruction; Pediatric neurosurgery; Radiation dose; Postoperative imaging | 2007 |
| 269 |
 |
Couldwell, William T. | Technique for methyl methacrylate cranioplasty to optimize cosmetic outcome | Background: Cranioplasty aims to reconstruct skull defects from fractures, decompressive craniectomies, tumors, and congenital anomalies in a cosmetically acceptable manner. We present a technique in methyl methacrylate cranioplasty that gives excellent cosmetic results by maintaining patient's calv... | | 2014-01-01 |
| 270 |
 |
Couldwell, William T.; Gillespie, David L.; Jensen, Randy L. | Identification of hypoxia-induced genes in a malignant glioma cell line (U-251) by cDNA microarray analysis | Overcoming the metabolic restrictions of hypoxia may allow the progression of lower-grade tumors to glioblastoma multiforme. Our findings of up-regulation of HIF-1α and its downstream targets VEGF, GLUT-1, and CAIX in higher-grade gliomas support this hypothesis. We compared the gene expression pro... | Glioblastoma multiforme; U-251; Hypoxia; Microarray analysis; Brain tumor; Depp; Astrocytoma | 2007 |
| 271 |
 |
Couldwell, William T. | Response to comment on: the combined transmastoid retro- and infralabyrinthine transjugular transcondylar transtubercular high cervical approach for resection of glomus jugulare tumors | We appreciate the comments by Dr. Sanna regarding our article (1). We recognize Dr. Sanna has much experience with these tumors and that, as cranial base surgeons, we should work as a team of neurosurgeons, otologists, and occasionally, head and neck surgeons and plastic surgeons. We also agree tha... | Jugular foramen tumor; Glomus jugulare tumors | 2007 |
| 272 |
 |
Couldwell, William T. | Multifocal inflammatory leukoencephalopathy associated with levamisole and 5-fluorouracil: case report | LEVAMISOLE AND 5-FLUOROURACIL have now become the standard chemotherapeutic regimen for patients with Stage 111 colon carcinoma. A case of multifocal inflammatory leukoencephalopathy secondary to levamisole alone or combination of levamisole and 5-fluorouracil is reported. Magnetic resonance imaging... | Autopsy; Levamisole; Multifocal inflammatory leukoencephalopathy | 1994 |
| 273 |
 |
Couldwell, William T. | Comparison of radiosurgery and conventional surgery for the treatment of glomus jugulare tumors | Object. The optimal management of glomus jugulare tumors remains controversial. Available treatments were once associated with poor outcomes and significant complication rates. Advances in skull base surgery and the delivery of radiation therapy by stereotactic radiosurgery have improved the results... | | 2004 |
| 274 |
 |
Couldwell, William T. | Enhanced protein kinase C activity correlates with the growth rate of malignant gliomas in vitro | Direct measurement of protein kinase C (PKC) activity in vitro revealed a significant increase in the activity of the enzyme in all human malignant glioma lines examined and the rat C6 tumor in comparison with control nonneoplastic astrocyte and mixed glial cultures. The total and particulate PKC ac... | Brain neoplasms; Flow cytometry; Glioma; Phorbol ester; Protein kinase C | 1991 |
| 275 |
 |
Dailey, Andrew T.; Schmidt, Meic H.; Apfelbaum, Ronald I. | Anterior fixation of odontoid fractures in an elderly population | Object. Fractures of the odontoid process are the most common fractures of the cervical spine in patients over the age of 70 years. The incidence of fracture nonunion in this population has been estimated to be 20-fold greater than that in patients under the age of 50 years if surgical stabilizatio... | Odontoid fractures; Elderly population; Anterior fixation | 2010 |
