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251 Schmidt, Meic H.Thoracoscopic vertebral body replacement with an expandable cage after ventral spinal canal decompressionOBJECTIVE: Minimally invasive thoracic anterior surgery using a thoracoscopic approach has evolved to include spinal biopsy, debridement, discectomy, decompressive corpectomy, interbody fusions, and internal fixations. Minimal access techniques can potentially decrease surgical access morbidity and...2007-01-01
252 Couldwell, William T.Initial experience related to the use of the Cosman-Roberts-Wells stereotactic instrumentInitial experience with a new arc-radius design of stereotactic frame that interfaced with the existing components of the Brown-Roberts-Wells instrument is reported. Over a 6-month period, 32 procedures were performed on 23 males and nine female patients (mean age 32 years); these included 27 ster...Image-directed stereotaxis; Stereotactic instrument; Cosman-Roberts-Wells stereotaxy1990
253 Kestle, John R. W.; Townsend, Jeannette J.; Brockmeyer, Douglas LeeJuvenile pilocytic astrocytoma of the brainstem in childrenObject. In reports involving the operative treatment of brainstem tumors, multiple histological types are often grouped together. To determine prognosis after resection, histology-specific data may be helpful. Methods. Twenty-eight patients with juvenile pilocytic astrocytoma (JPA) of the brainste...Juvenile pilocytic astrocytoma; JPA; Brainstem tumors; Resection2004
254 Couldwell, William T.; Viskochil, David H.; Fults, Daniel WebsterMolecular, genetic, and cellular pathogenesis of neurofibromas and surgical implicationsNEUROFIBROMATOSIS 1 (NF1) IS A common autosomal dominant disease characterized by complex and multicellular neurofibroma tumors. Significant advances have been made in the research of the cellular, genetic, and molecular biology of NF1. The NF1 gene was identified by positional cloning. The function...Loss of heterozygosity; Malignant peripheral nerve sheath tumor; Plexiform Neurofibroma; Spinal neurofibroma2006
255 Kestle, John R. W.Death after late failure of third ventriculostomy in childrenLate failure following successful third ventriculostomy for obstructive hydrocephalus is rare, and death caused by failure of a previously successful third ventriculostomy has been reported only once. The authors present three patients who died as a result of increased intracranial pressure (ICP) a...Ventriculostomy; Obstructive hydrocephalus; Late failure; Death2002
256 Kestle, John R. W.Assessing the validity of the endoscopic shunt insertion trial: did surgical experience affect the results?Object. Most surgical procedures are associated with a learning curve in which the success rate is lower early in the experience before mistakes have been identified and modifications made to the procedure. Negative results obtained early in a trial's learning curve may be a matter of timing rather ...Endoscopic shunt insertion; Ventriculoperitoneal shunt; Pediatric neurosurgery; Surgical experience2004-01-01
257 Schmidt, Meic H.Spinal meningiomas: surgical management and outcomeAdvances in imaging and surgical technique have improved the treatment of spinal meningiomas; these include magnetic resonance imaging, intraoperative ultrasonography, neuromonitoring, the operative microscope, and ultrasonic cavitation aspirators. This study is a retrospective review of all patient...Spinal meningioma; Spinal tumor; Intradural; Extramedullary2003
258 Couldwell, William T.Neurosurgical workforce trends in the United StatesObject. The purpose of this study was to evaluate the US neurosurgery workforce by reviewing journal recruitment advertisements published during the past 10 years. Methods. The number of available academic and private neurosurgical staff positions was determined based on recruitment advertisements ...2005-02
259 Couldwell, William T.Posterior fossa brain tumors and arterial hypertensionHypertension caused by arterial compression of the rostral ventrolateral medulla is well described. Much less information is available on the association between neurogenic hypertension and posterior fossa brain tumors. To date, multiple reports have supported the impression that a small subpopulat...Posterior fossa tumors; Brain stem; Arterial hypertension; Essential hypertension; EHTN2006
260 Kestle, John R. W.Propionibacterium encephalitis [Letter to the editor]To THE EDITOR: We read with interest the article by Camarata, et al., reporting two cases of dorsal midbrain encephalitis (Camarata PJ, McGeachie RE, Haines S J: Dorsal midbrain encephalitis caused by Propionibacterium aches. Report of two cases. J Neurosurg 72." 654-659, April, 1990). There are...1990
261 Bisson, Erica F.Management of distraction injury of the lumbosacral junction with unilateral perched facetBackground: Traumatic unilateral facet dislocation without fracture is an uncommon injury of the lumbosacral junction. We describe a case of a unilateral perched L5-S1 facet causing axial back pain and radiculopathy provoked by motion. ...Spine surgery, Facet dislocation, operative management, trauma, neurosurgery2011-01-04
262 Couldwell, William T.Pallidotomy in advanced Parkinson's diseaseTo the Editor: We read with interest the comments published regarding our recent article on pallidotomy in patients with advanced Parkinson's disease (3). There seems to be confusion as to some of the technical methods used in creating the radiofrequency lesions in these patients. As noted in the Pa...Pallidotomy; Dyskinesia1995
263 Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A.Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-assoc...Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex2006-07-11
264 Couldwell, William T.Increased invasive capacity of connexin43-overexpressing malignant glioma cellsObject. Malignant glioma cells, similar to astrocytes, express connexin43 (Cx43) universally but at widely varied levels. Data from previous studies have demonstrated that malignant glioma cells form functional gap junction channels among themselves as well as with astrocytes and that such a communi...2003-12
265 Couldwell, William T.Protein kinase C and growth regulation in malignant gliomasTo the Editor: The presence of amplified growth factor systems in many tumor models, including malignant gliomas, raises the question of how such external signals are transduced into a transformed phenotype (increased proliferation, invasion, lack of contact inhibition, angiogenic capacity, etc.). ...Protein kinase C; Glioma; Brain neoplasm; protooncogenes; Apoptosis; Tamoxifen1994
266 Couldwell, William T.No ordinary time, no ordinary men: the relationship between Harvey Cushing and Franklin D. Roosevelt, 1928-1939The authors elucidate the strong personal relationship that developed between Dr. Harvey Cushing and Franklin Delano Roosevelt (FDR) from 1928 to 1939, as manifested in their frequent letters to each other. The relationship was initiated by the marriage of their children. Through his correspondence ...2001
267 Schmidt, Meic H.NASA light-emitting diode medical program-progress in space flight and terrestrial applicationsThis work is supported and managed through the NASA Marshall Space Flight Center - SBIR Program. Studies on cells exposed to microgravity and hypergravity indicate that human cells need gravity to stimulate cell growth. As the gravitational force increases or decreases, the cell function responds in...Terrestrial applications; Cell growth; NASA; Microgravity environment2000
268 Couldwell, William T.Distal ventriculoperitoneal shunt failure secondary to Clostridium Difficile ColitisDistal ventriculoperitoneal shunt obstruction is typically associated with cerebrospinal fluid (CSF) infection, fluid pseudocysts, bowel obstruction, bowel perforation, or improper shunt placement in the abdomen. We describe a unique etiology for distal shunt obstruction secondary to Clostridium dif...Shunt Failure2005-03
269 Couldwell, William T.Medpor implant in cranioorbitomaxillary reconstruction: institutional experience and a review of the literatureAutologous materials remain the gold standard for complex skull base and craniofacial reconstruction, but they carry additional morbidity associated with the second harvest procedure and with prolonged operation time. These autologous materials also resorb in a way that is not predictable, rendering...Medpor; Alloplastic material; Autogenous tissue; Craniofacial reconstruction; Skull base surgery; Methylmethacrylate; Silicone2008
270 Schmidt, Meic H.Diagnosis and management of sacral Tarlov cystsPerineurial (Tarlov) cysts are meningeal dilations of the posterior spinal nerve root sheath that most often affect sacral roots and can cause a progressive painful radiculopathy. Tarlov cysts are most commonly diagnosed by lumbosacral magnetic resonance imaging and can often be demonstrated by com...Tarlov cysts; Meningeal dilations; Spinal lesion; Outcome2003
271 Couldwell, William T.Unruptured posterior communicating artery aneurysm presenting with gustatory seizures and temporal lobe edemaUnruptured cerebral aneurysms presenting with seizures are unusual. We describe a case of a growing middle cerebral artery aneurysm presenting with gustatory seizures with magnetic resonance imaging showing peri-aneurysmal edema. This case is the first to show temporal lobe edema associated with inc...Seizure; Brain edema; PCOM2009-04
272 Dailey, Andrew T.; Brodke, Darrel S.Utility of helical computed tomography in differentiating unilateraland bilateral facet dislocationsObjective: Diagnosis of cervical facet dislocation is difficult when relying on plain radiographs alone. This study evaluates the interobserver reliability of helical computed tomography (CT) in the assessment of cervical translational injuries, correlates the radiographic diagnosis with intraoper...Facet dislocations; Helical computed tomography; Spinal trauma2009
273 Couldwell, William T.Cranioplasty with the Medpor porous polyethylene Flexblock implantThe authors describe the use of a porous polyethylene Flexblock implant for cosmetic cranioplasty. The implant may be used to cover any small- or medium-sized (< 8 cm) cranial defect, offering similar cosmetic results to standard alloplast cranioplasty while decreasing operation time. The porous i...Cranioplasty; Medpor; Alloplast; Polyethylene; Skull defect1994
274 Couldwell, William T.Cholesteatoma of the clivus case reportObjective: Cholesteatomas (CNS epidermoids) can be found intradurally or extradurally in the central nervous system. Extradural intraosseous lesions are most commonly found in the petrous bone. Design: Case report Clinical Presentation: The authors describe a unique case of a clival cholesteatoma o...2006-01-01
275 Kestle, John R. W.Natural history of cerebral cavernous malformationsTo determine the natural history of brain cavernous malformations, the authors entered patients referred to their center into a prospective registry between 1987 and 1993. All patients underwent magnetic resonance imaging, which showed the typical appearance of this lesion, and conservative manageme...Cavernous malformation; Vascular malformation; Seizure1995
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