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CreatorTitleDescriptionSubjectDate
251 Mitchell, Joyce A.Getting around in a large nomenclature file: browsing SNOMED internationalWe have developed a means whereby we can easily browse a very large (s 30 MB) file of a nomenclature vocabulary. "SNOMED International - A Vocabulary of Human and Veterinary Medicine" is such a file and has been proposed to serve as the basis for controlled vocabularies. The College of American Path...1994-01-01
252 Mitchell, Joyce A.Beyond relevance--characteristics of key papers for clinicians: an exploratory study in an academic settingObjective: The purpose of this study was to determine what factors beyond relevance influence a clinician's decision to choose to read one journal article over another in satisfying an information need. Design: Seventeen health care providers were interviewed and then surveyed regarding the characte...1996-01-01
253 Mitchell, Joyce A.Construction of a medical informatics thesaurusMedical Informatics needs a specific terminology that reflects the multi-disciplinary nature of the field and can rapidly change as the discipline evolves. Using the four primary methods of thesaurus construction, a group at the University of Missouri- Columbia is developing a thesaurus that meets t...1994-01-01
254 Mitchell, Joyce A.The creation and early implementation of a high speed fiber optic network for a university health sciences centerIn late 1989 the University of Missouri Health Sciences Center began the process of creating an extensive fiber optic network throughout its facilities, with the intent to provide networked computer access to anyone in the Center desiring such access, regardless of geographic location or organizatio...1991-01-01
255 Mitchell, Joyce A.A decision-support system for the analysis of clinical practice patternsSeveral studies documented substantial variation in medical practice patterns, but physicians often do not have adequate information on the cumulative clinical and financial effects of their decisions. The purpose of developing an expert system for the analysis of clinical practice patterns was to a...1994-01-01
256 Mitchell, Joyce A.The columbia registry of controlled clinical computer trialsNumerous reports on randomized controlled clinical trials of comnputer-based interventions have been published. These trials provide useful evaluations of the impact of information technology on patient care. Unfortunately, several obstacles make access to the trial reports difficult. Barriers inclu...1992-01-01
257 Hall, Eric S.Aiding clinicians through summarization of perinatal dataExploratory analysis has focused on developing summarized views of monitor-captured perinatal data to support adherence to established clinical protocols. In addition to facilitating rapid access to significant clinical trends and reducing subjective interpretation of monitor-captured data, combini...Perinatal data; Perinatal care; Trapeze Interactive Poster2009-09-23
258 DuVall, Scott L.Automatic, near real-time reporting of communicable diseases via web syndicationReal-time, automatic surveillance of reportable diseases remains an obstacle in Public Health. Reports are generated manually by healthcare provided and sent to local or state public health offices. Web syndication is the way to publish and transmit information to subscribed users. This is typicall...Web syndication; Electronic reporting; Real-time reporting; Trapeze Interactive Poster2009-09-23
259 Narus, Scott P.; Hales, Joseph W.; Poynton, Mollie Rebecca; Evans, R. ScottEnhancing continuity of care through an emergency medical card at Intermountain Healthcare: using the continuity of care record standardComplex and fragmented healthcare systems hamper provision of effective care where it is needed most. 1 In most instances, continuity of care is rarely considered during referral, transfer, or discharge of patients from one caregiver to another. 2,3 The dearth of pertinent current and historical hea...Continuity of care; Emergency medical card; Trapeze Interactive Poster2009
260 DuVall, Scott L.Identifying data set specific duplicate patient recordsProbabilistic models are commonly used in the identification of duplicate records. These methods are usually more accurate than deterministic methods, but are exponentially more computationally complex. Thus to make them computationally feasible, they rely on deterministic blocking strategies. Th...Probabilistic models; Duplicate records; Duplicate patient records; Trapeze Interactive Poster2009
261 Camp, Nicola J.Genetic susceptibility of prostate cancer: genome-wide screen of "non-aggressive" diseaseResearch has consistently shown that genetics plays a critical role in prostate cancer (CaP) development, but the identification of CaP genes has proven to be very difficult. Hereditary prostate cancer is a complex disease believed to involve numerous genes and variable penetrance. It has been propo...CaP genes; Prostate cancer; Non-aggressive; Utah Population Database; Trapeze Interactive Poster2009
262 Robison, Reid Justin; Farley, Megan A.; Cannon, Dale Sherman; Allen Brady, Kristina Lisa; Matsunami, Norisada; Stevens, Jeffery; Baird, Lisa M.; Varvil, Tena; Leppert, Mark F.; McMahon, William M.; Coon, Hilary H.Copy number variation in a follow-up of adults with ASD: a behavioral phenotype-genotype studyAutistic Spectrum Disorders (ASD) are a set of complex, early-onset neurodevelopmental disorders. Recent studies have revealed a complex genetic landscape for ASD, with many potential genes involved. Little is known about the long-term outcome of individuals with ASD who were diagnosed in childhoo...Autistic spectrum disorders; Copy number variation; Genotyping; Trapeze Interactive Poster2010-03-15
263 DuVall, Scott L.Creation of an open source master person index from proprietary code: the open source "care data exchange" projectFrom 1998 to 2004 the ""Care Data Exchange"" (CDE) software was developed as a proprietary product by CareScience for the California HealthCare Foundation (CHCF). In 2005 CHCF asked Forrester Research to study the feasibility of releasing the CDE software assets under a free, open source license. Th...Care Data Exchange; CDE; Proprietary code; Forrester report; Trapeze Interactive Poster2009
264 Frey, Lewis J.Enhancing caBIG™ workflow for multi-tier distributionIntroduction caBIG™ Integration caBIG™ provides a GRID based application environment with data abstraction and vocabulary services, workflow management and a security framework. Sensor Abstraction Interface It is proposed to provide a sensor abstraction interface, using caDSR, enabling caBIG...caBIG; Sensor abstraction interface; Multi-tier distribution; Trapeze Interactive Poster2009
265 Camp, Nicola J.Genome-wide linkage analysis for aggressive prostate cancer in Utah high risk pedigreesResearch has consistently shown that genetics plays a critical role in prostate cancer (CaP) development, but the identification of CaP genes has proven to be very difficult. Hereditary prostate cancer is a complex disease involving numerous genes and variable phenotypic expression. This heterogene...Linkage analysis; Aggressive prostate cancer; CaP genes; ICPCG; Utah; Trapeze Interactive Poster2009
266 Mitchell, Joyce A.Integrating genetic information resources with an EHRThe integration between the electronic health record (HER) and on0line information resources, using tools such as "infobuttons", is considered a promising solution to fulfill clinicians' information needs at the point-of-care. This article describes the implementation of "infobutton" links from a...Electronic health record; HER; Infobutton links; Genetics Home Reference; GHR; GeneTests; Genetic information resources; Trapeze Interactive Poster2009
267 Camp, Nicola J.Survey of excess familiality in prostate cancerProstate cancer (PCa) is the most commonly diagnosed cancer among men, and has long been recognized to occur in familial clusters. However, identification of genes predisposing individuals to prostate cancer has been difficult. Putative PCa predisposition loci identified by genetic linkage have been...Prostate cancer; Utah Population Database; Linkage analysis; Familial compotent; Excess familiality; Trapeze Interactive Poster2009
268 DuVall, Scott L.Understanding the profile of errors that cause duplicate entries in a patient registryDuplicate records are detrimental to the cost-effective and efficient delivery of health care. Manually identifying and resolving duplicates can cost $60 per case. Patterns have been found in the types of errors that occur in patient registries, suggesting that undetected duplicate records may be ...Duplicate records; Duplicate patient records; Profile of errors; Enterprise Data Warehouse; EDW; Utah Population Database; UPDB; Trapeze Interactive Poster2009
269 Camp, Nicola J.SumLINK statistic for linkage analysis: application to the ICPCG pooled linkage resourceWe propose a novel, genome-wide, linkagebased statistic, "sumLINK," for identification of disease susceptibility loci. Our approach focuses primarily on "linked" pedigrees (those with pedigree-specific LOD ? 0.588; equivalent to unadjusted p ? 0.05) to identify regions of extreme consistency across ...SumLINK; Linkage analysis; ICPCG; Disease susceptibility loci; Trapeze Interactive Poster2009
270 DuVall, Scott L.Preserving academic poster contentPosters are an important way to share information between academia and industry. They are presented at national conferences, regional meetings, and even in university departments. There were almost 75,000 calls for poster submissions last year alone. Most posters are presented for only a few hours...Poster preservation; Trapeze Interactive Poster2009
271 Frey, Lewis J.ca! - emergency and disaster recovery system extensions to caBIG™During Hurricane Katrina, US Federal and State Agencies had disparate data acquisition systems, separate data networks and unique incompatible applications. •System incompatibilities exist even between various Federal agencies. •Consistent data available to one agency should be available to an...caBIG; Data acquisition systems; Data sharing; Information sharing; Trapeze Interactive Poster2009-09-23
272 Blumenthal, Donald K.Identification of the calmodulin-binding domain of skeletal muscle myosin lightIn the course of determining the primary structure of rabbit skeletal muscle myosin light chain kinase (MLCK; ATP:protein phosphotransferase, EC 2.7.1.37) a peptide fragment was obtained that appears to represent the calmodulin-binding domain of this enzyme. Low concentrations of the peptide inhibit...Peptides; Enzymes; Protein sequence1985-05
273 Blumenthal, Donald K.Identification of the substrate and pseudosubstrate binding sites of phosphorylase kinase gamma-subunit.Using site-directed mutagenesis, we proposed that an autoinhibitory domain(s) is located at the C-terminal region (301-386) of the phosphorylase kinase gamma-subunit (Huang, C.-Y.F., Yuan C.-J., Livanova, N.B., and Graves, D.J. (1993) Mol. Cell. Biochem. 127/128, 7-18). Removal of the putative inhib...Mutagenesis; Autoinhibitory Domain; Peptides1995-03-31
274 Blumenthal, Donald K.Effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding.Using site-directed mutagenesis we have expressed in Escherichia coli three engineered calmodulins (CaM) containing deletions in the solvent-exposed region of the central helix. These are CaM delta 84, Glu-84 removed; CaM delta 83-84, Glu-83 and Glu-84 removed; and CaM delta 81-84, Ser-81 through Gl...Drug Effects; Genetics; Metabolism1989-05-15
275 Huser, Vojtech; Rocha, Roberto A.RetroGuide: Conducting Time Series Analyses on Large Data Sets: a Case Study With LymphomaWe describe the application of our previously developed analytical infrastructure called RetroGuide to conduct an observational retrospective cohort study using a clinician friendly flowchart approach.Retroguide; Analysis of data; Biomedical informatics; EHR; lymphoma; Case study; Knowledge representation; Cancer; Retrospective study2008-03-28
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