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Creator | Title | Description | Subject | Date |
| 226 |
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Capecchi, Mario R. | Hox genes and mammalian development | We have examined the interactions of Hox genes in forming a cervical vertebrae, hindbrain, and limbs. In each case, it is apparent that individual Hox genes are performing individual functions but that more profound roles are apparent when they act in combination with others Hox genes. The observed ... | Drosophila; Gene Expression Regulation, Developmental; Homozygote | 1997 |
| 227 |
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Olivera, Baldomero M.; McIntosh, J. Michael | Novel post-translational modification involving bromination of tryptophan: identification of the residue, L-6-bromotryptophan, in peptides from Conus imperialis and Conus radiatus venom | We report a novel post-translational modification involving halogenation of tryptophan in peptides recovered from the venom of carnivorous marine cone snails (Conus). The residue, L-6-bromotryptophan, was identified in the sequence of a heptapeptide, isolated from Conus imperialis, a worm-hunting... | Conotoxins; Conus imperialis; Conus radiatus; L-6-bromotryptophan | 1997 |
| 228 |
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Jorgensen, Erik | Neural plasticity | Neural plasticity refers to functional changes in the nervous system and therefore encompasses a range of phenomena from changes at synapses observed on a microscopic scale to changes in behavior observed in the whole animal. These diverse phenomena are related since changes in synapses are believ... | Synapses; Nervous System; Development | 1997 |
| 229 |
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Bohs, Lynn A. | Phylogenetic relationships in Solanum (Solanaceae) based on ndhF sequences | A phylogenetic analysis was conducted using sequence data from the chloroplast gene ndhF. Sequences were obtained from 25 species of Solanaceae, including 18 species of Solanum representing five of the seven conventionally recognized subgenera. | Solanum; ndhF | 1997 |
| 230 |
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| Franklin Institute award dinner and ceremony held May 1, 1997 | This is a 1 hour, 42 minutes, 53 seconds video of the 1997 Franklin Institute Awards Banquet and Ceremony. The awards included a summary of each winner's achievements, the presentation of the award, and an acceptance speech. The award winners included Ralph L. Brinster, the Bower Award and Prize f... | Transgenic mice; Gene targeting; Genetic engineering; Molecular genetics; Mutagenesis; Homeobox genes; Histology - Pathological; Gene expression; Gene regulation; Genotype; Phenotype | 1997 |
| 231 |
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Beckerle, Mary C. | Comparison of three members of the cysteine-rich protein family reveals functional conservation and divergent patterns of gene expression | Members of the cysteine-rich protein (CRP) family are evolutionarily conserved proteins that have been implicated in the processes of cell proliferation and differentiation. In particular, one CRP family member has been shown to be an essential regulator of cardiac and skeletal muscle development. | LIM domains; Chicken fibroblasts; Zyxin; Actinin; Protein expression; Cysteine-rich proteins | 1997 |
| 232 |
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Goller, Franz | Vocal gestures of shared syllable types in cardinals | In songbirds, songs are learned by memorization and copying of tutor song and such copies can be remarkably accurate. However, it is not known whether acoustic similarity is generated by equally similar vocal gestures. We studied syringeal and respiratory motor patterns of syllable types shared by u... | Cardinalis cardinalis; Vocal gestures; Birdsong syllables; Song syllables | 1997 |
| 233 |
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Gesteland, Raymond F.; Atkins, John F.; Felden, Brice; McCutcheon, John P. | Probing the structure of the Escherichia coli 10Sa RNA (tmRNA) | The conformation of the Escherichia coli 10Sa RNA (tmRNA) in solution was investigated using chemical and enzymatic probes. Single- and double-stranded domains were identified by hydrolysis of tmRNA in imidazole buffer and by lead(II)-induced cleavages. Ribonucleases T1 and S1 were used to map unpai... | Covariation; Pseudoknot; Structural Probing; 10Sa RNA; tmRNA | 1997 |
| 234 |
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Beckerle, Mary C. | CRP1, a LIM domain protein implicated in muscle differentiation, interacts with α-actinin | Members of the cysteine-rich protein (CRP) family are LIM domain proteins that have been implicated in muscle differentiation. One strategy for defining the mechanism by which CRPs potentiate myogenesis is to characterize the repertoire of CRP binding partners. | CRP1; Cysteine-rich proteins; Actinin; Protein-protein interactions; LIM domains | 1997 |
| 235 |
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Goller, Franz | Inspiratory muscle activity during singing in zebra finches and cowbirds | Singing is produced by an intricate coordination of vocal (syringeal) and respiratory muscles. Expiratory muscle activity is associated with the production of notes and syllables, which are separated by silent intervals, negative air sac pressure, and inspiratory air flow. In order to study the mus... | Minibreath; Expiration; Inspiration | 1997 |
| 236 |
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Seger, Jon | Natural history and evolution of paper-wasps | Paper-wasps occupy a special place in the history of animal behavior. Temperate species o f Polistes are large, beautiful, intelligent, adaptable, easy to observe, and thoroughly committed to social life. They are also aptly named, being intensely political, in the limited sense that any nonhuman an... | Individuals; Excellent; Phylogeny | 1997 |
| 237 |
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Ehleringer, James R. | Burning coal seams in southern Utah: a natural system for studies of plant responses to elevated CO2 | In the Burning Hills and Smoky Mountains of southern Utah (USA), coal deposits exposed to the surface have been ignited by lightning and have been burning for periods of years to over a century. We examined one of these sites, where the below-ground combustion of this low-sulfur coal releases gases ... | Coal fires; Elevated CO2; Isotope ratios; Atriplex confertifolia; Salsola iberica; Gutierrezia sarothrae | 1997 |
| 238 |
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Olivera, Baldomero M.; McIntosh, J. Michael | α-Conotoxin MII blocks nicotine-stimulated dopamine release in rat striatal synaptosomes | Activation of presynaptic nicotinic acetylcholine receptors (nAChRs) can induce the release of neurotransmitters such as dopamine and norepinephrine in the CNS. Accumulating evidence suggests that distinct nAChR subtypes are involved; however, it has been difficult to determine the subunit composit... | Conotoxins; a-Conotoxin MII | 1997 |
| 239 |
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Davidson, Diane W. | Experimental studies of species-specificity in cecropia-ant relationships | Strict coevolution requires that interactions among organisms be speciesspecific. We assessed the relative roles of host- and habitat-specificity in determining the match between a genus of myrmecophytic trees and a guild of obligate plant-ants in the moist tropical forests of Madre de Dios, Peru. F... | Ant-plant; Ants; Cecropia; Coevolution; Colonization; Coordinated dispersal; Ecological fitting; Habitat-specificity; Host-specificity; Mutualism; Parasitoid wasps; Preadaptation | 1997 |
| 240 |
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Jorgensen, Erik | Caenorhabditis elegans rab-3 mutant synapses exhibit impaired function and are partially depleted of vesicles | Rab molecules regulate vesicular trafficking in many different exocytic and endocytic transport pathways in eukaryotic cells. In neurons, rab3 has been proposed to play a crucial role in regulating synaptic vesicle release. To elucidate the role of rab3 in synaptic transmission, we isolated and cha... | | 1997 |
| 241 |
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Bohs, Lynn A. | Solanum maternum (Solanaceae), a new Bolivian relative of the tree tomato | A new species endemic to Bolivia, Solanum maternum, is described. Solanum maternum belongs to a group of taxa formerly recognized as the genus Cyphomandra. Solanum maternum is morphologically very similar to the tree tomato, Solanum betaceum, and may be its closest wild relative. | Solanum maternum; Cyphomandra | 1997 |
| 242 |
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Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. Michael | Differential targeting of nicotinic acetylcholine receptors by novel αA-conotoxins | We describe the isolation and characterization of two peptide toxins from Conus ermineus venom targeted to nicotinic acetylcholine receptors (nAChRs). The peptide structures have been confirmed by mass spectrometry and chemical synthesis. In contrast to the 12-18 residue, 4 Cys-containing α-co... | Conotoxins; aA-conotoxins; Conus ermineus; Peptide toxins | 1997 |
| 243 |
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Olivera, Baldomero M. | Conus venom peptides, receptor and ion channel targets, and drug design: 50 million years of neuropharmacology | The predatory cone snails (Conus) are among the most successful living marine animals (~500 living species). Each Conus species is a specialist in neuropharmacology, and uses venom to capture prey, to escape from and defend against predators and possibly to deter competitors. An individual cone... | Conotoxins | 1997 |
| 244 |
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Goller, Franz | Muscular control and biomechanics of the songbird syrinx | In songbirds the vocal organ, the syrinx, is controlled by six bilateral muscles, the functional roles of which have been studied indirectly, but not directly. We filmed the syrinx with an endoscope while electrically stimulating individual intrinsic muscles on one side. | Syringeal; Medial labium; Vocal organ | 1997 |
| 245 |
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Coley, Phyllis D. | Vesicular-arbuscular mycorrhizae in two tropical monodominant trees | Mycorrhizae, symbioses between plant roots and fungi, are found in virtually all terrestrial plant ecosystems. Substantial evidence indicates that mycorrhizal associations are beneficial to both partners. | Ectromycorrizae; Flooding; Monodominance; Neotropics; Vesicular-arbuscular mycorrhizae; Mora excelsa; Prioria copaifera | 1997 |
| 246 |
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Clayton, Dale H. | Two new species of Dennyus (Ctenodennyus) lice (Phthiraptera: Menoponidae) from swiftlets (Apodiformes: Apodidae) | To date, only a single species of Dennyus (Ctenodennyus) has been described, this being D. (C.) spiniger Ewing from Cypseloides niger borealis (Kennedy), the northern black swift in North America. Through extensive collecting of lice by the junior author from swiftlets and through a loan of Bishop M... | Apodidae; Menoponidae; Ctenodennyus; Dennyus spiniger; Dennyus southwoodi; Dennyus elbeli | 1997 |
| 247 |
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Torti, Sylvia D.; Coley, Phyllis D. | Vesicular-arbuscular mycorrhizae in two tropical monodominant trees | Mycorrhizae, symbioses between plant roots and fungi, are in virtually all terrestrial plant ecosystems. Substantial evidence indicates that mycorrhizal associations are beneficial to both partners. In most systems, the fungus benefits the host plant by effectively scavenging nutrients and in return... | Monodominance; Ectomycorrhizae; Flooding; Neotropics; Vesicular-arbuscular mycorrizae; Mora excelsa; Prioria copaifera | 1997 |
| 248 |
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Beckerle, Mary C. | Molecular dissection of a LIM domain | LIM domains are novel sequence elements that are found in more than 60 gene products, many of which function as key regulators of developmental pathways. The LIM domain, characterized by the cysteine-rich consensus CX2CX16_23HX2CX2CX2CX16_21CX2-3(C/H/ D), is a specific metal-binding structure tha... | LIM domains; Metal-binding; Zyxin; Cysteine-rich proteins | 1997 |
| 249 |
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Beckerle, Mary C. | Nuclear-cytoplasmic shuttling of the focal contact protein, zyxin: a potential mechanism for communication between sites of cell adhesion and the nucleus | Integrin-dependent cell adhesion to specific extracellular matrix molecules has been demonstrated to trigger dramatic changes in gene expression that can affect cell fate. However, little is understood about the molecular mechanism by which events at sites of cell-substratum adhesion are communicate... | Zyxin; Cytosol; Nuclear export signal | 1997 |
| 250 |
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Olivera, Baldomero M. | Alternative splicing in the pore-forming region of shaker potassium channels | We have cloned cDNAs for the shaker potassium channel gene from the spiny lobster Panulirus interruptus. As previously found in Drosophila, there is alternative splicing at the 59 and 39 ends of the coding region. However, in Panulirus shaker, alternative splicing also occurs within the pore-forming... | Panulirus interruptus; Conotoxins; Shaker; Stomatogastric ganglion; Pore-forming region; Alternative splicing | 1997 |
