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Creator | Title | Description | Subject | Date |
| 1 |
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Gesteland, Raymond F. | Translation of Rl7 RNA fragments | Examination of the events during infection of cells by RNA phages reveals phemonomena that are surprisingly complex for a virus that has only enough information to code for three to four proteins. The coat protein is synthesized at a rapid rate through most of the infectious cycle making it the pre... | Electrophoresis; RNA, Messenger; Peptide Biosynthesis; Kinetics | 1969 |
| 2 |
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Gesteland, Raymond F. | Characterization of lysozyme messenger and lysozyme synthesized in vitro | In vitro systems for protein systhesis have been in wide use for about 10 years. In most of the early work protein synthesis was measured by following the incorporation of radioactive amino acids into acid precipitable material. This test cannot distinguish between the synthesis of complete, activ... | Lysozyme Messenger; Lysozyme Synthesized; Protein Synthesis | 1969 |
| 3 |
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Gesteland, Raymond F. | Pattern of protein synthesis in monkey cells infected by simian virus 40 | After infection of several permanent monkey cell lines by simian virus 40 (SV40), four additional protein bands can be detected by simple sodium dodecyl sulfate-polyacrylamide gel electrophoresis of whole-cell extracts. These bands appear only after the onset of viral deoxyribonucleic acid (DNA) syn... | Monkeys; Simian virus 40; Peptides; DNA, Viral/biosynthesis | 1972 |
| 4 |
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Gesteland, Raymond F. | Processing of adenovirus 2-induced proteins | Analysis of (35)S-methionine-labeled extracts of adenovirus 2-infected KB cells revealed 22 virus-induced polypeptide components. Most proteins of the virion were easily detected in extracts of whole cells labeled for short periods between 15 and 30 h after infection; however, several virion compone... | Adenoviridae; Viral Proteins; Protein Precursors; Methionine; Mouth Neoplasms | 1973 |
| 5 |
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Normann, Richard A. | Control of retinal sensitivity. I. Light and dark adaptation of vertebrate rods and cones | Rods and cones in Necturus respond with graded hyperpolarization to test flashes spanning about 3.5 log units of intensity. Steady background levels hyperpolarize the rods, and the rod responses become progressively smaller as background level is increased. In cones, higher background levels reduce... | Retina;Light and Dark Adaptation; Recepters; Bipolars; Ganglion Cells | 1974 |
| 6 |
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Gesteland, Raymond F.; Atkins, John F. | Origin and destiny of adenovirus proteins | Lytic infection of human cells by adenovirus proceeds by a temporal expression of genes. Classically two phases have been defined: an early phase, which includes events occurring before the onset of DNA synthesis (8 hours), and a late phase, including events whose existence depends on the onset of... | Protein Biosynthesis; DNA, Viral; Adenoviridae; RNA, Viral; Time Factors | 1975 |
| 7 |
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Normann, Richard A. | Oscillations in rod and horizontal cell membrane potential: evidence for feed-back to rods in the vertebrate retina | 1. Rods and horizontal cells were studied with intracellular recordings in the retina of the toad, Bufo marinus; 161 cells were from the eyecup preparation and thirty were from the isolated perfused retina. 2. Of these cells, 39% exhibited either transient or sustained oscillations of membrane poten... | Retina; Photoreceptors; Toads; Adaptation, Ocular | 1976 |
| 8 |
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Horch, Kenneth W. | Acoustic interneurons of fiddler and ghost crabs | The properties of acoustic interneurons in fiddler (Uca pugilalor and U. minax) and ghost (Ocvpade qucldrula) crabs are described, as revealed bv tests with pure tones. Three types of interneurons were present in all species: tonic, which fired for the duration of the stimulus; phasic, which fire... | Acoustic crabs; Neural recording; Vibration reception | 1976 |
| 9 |
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Gesteland, Raymond F. | Simian virus 40-specific polypeptides in Ad2+ND4- infected cells | A comparison of the proteins synthesized in human cells at late times after infection with adenovirus (Ad2) and with the adeno-simian virus 40 (SV40) hybrid viruses revealed polypeptides of 30,000 and 92,000 molecular weight specific for the hybrid viruses Ad2+ND1 and Ad2+ND4, respectively. Cell-fre... | Molecular Weight; Peptide Biosynthesis; RNA, Messenger; Viral Proteins | 1976 |
| 10 |
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Gesteland, Raymond F. | Cell-free synthesis of herpes simplex virus proteins | Polyribosomes isolated from herpes simplex virus type I (HSV-1)-infected cells have been used to program a eucaryotic cell-free translation system. At least 10 HSV-specific polypeptides, with apparent molecular weights of 25,000 to 160,000, are synthesized by wild-type HSV-infected polyribosomes. Po... | Viral Proteins; Herpes Simplex; Peptide Biosynthesis; Thymidine Kinase | 1977 |
| 11 |
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Normann, Richard A. | Effects of background illumination on the photoresponses of red and green cones | 1. The photoresponses of light- and dark-adapted red and green cone photoreceptors were recorded intracellularly in the retina of the turtle, Pseduemys scripta elegans. Background illumination produced similar effects on both types of cones. 2. In response to the onset of a prolonged, steady backgro... | Turtles; Adaptation, Ocular; Retina; Signal Transmission | 1979 |
| 12 |
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Normann, Richard A. | Signal transmission from red cones to horizontal cells in the turtle retina | 1. Intracellular recordings were made from L-type horizontal cells in the retina of the turtle Pseudemys scripta elegans. The responses were evoked by 500 msec pulses of 'white' light. 2. L-type horizontal cells were classified as either, 'small receptive field' s.r.f. or 'large receptive field' l.r... | Turtles; Synapses; Retina; Photoreceptors | 1979 |
| 13 |
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Horch, Kenneth W. | On the number and nature of regenerating myelinated axons after lesions of cutaneous nerves in the cat | 1. Electrophysiological and anatomical techniques were used to investigate normal and regenerating sural and posterior femoral cutaneous nerve fibres in the cat. 2. One and a half years after transection of these nerves it was found that the regenerating neurones supported multiple sprouts in the... | Nerve fibres; Transection; Nerve injury | 1981 |
| 14 |
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Horch, Kenneth W. | Changes in primary afferent depolarization of sensory neurones during peripheral nerve regeneration in the cat | I. Micro-electrode recordings were made from normal and regenerating sural nerve fibres in cats. Increases in the excitability of the central terminals of these fibres after conditioning stimulation of other sural nerve fibres were taken as evidence for primary afferent depolarization. 2. At all... | Micro-electrode recording; Nerve regeneration; Primary afferent depolarization | 1981 |
| 15 |
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Christensen, Douglas A. | Effects of increased energy prices on U.S. agriculture: an econometric approach | Although the contents of this manuscript remain the responsibility of the authors, we wish to thanks a group of reviewers for the time and conscientious effort they put forth to solidify this final draft. Andrew Morton, Brian Holding, Wesley Buchele, and Arnold Paulsen deserve much credit for their ... | Energy prices | 1981 |
| 16 |
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Horch, Kenneth W.; Tuckett, Robert P.; Burgess, Paul Richard | Neural signal for skin indentation depth. I. Changing indentations | Psychophysical tests on human subjects showed that judgments of skin indentation depth made when the fingertip was indented at rates from 0.2 to 16 mm/set were quite insensitive to changes in indentation velocity. Similar results were obtained on the forearm at indentation velocities of 0.4 to 16... | Skin; Indentation; Nerve impulses | 1983 |
| 17 |
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Christensen, Douglas A. | Interface of forest and agriculture in nonpoint pollution control | Management practices of agriculture, including conservation and tillage options, recently have received a great deal of attention with respect to their impact upon the environment. Research efforts have focused both on the direct impacts of reduced on-site productivity resulting from the erosion of ... | Suspended sediment; Channel erosion; Silviculture | 1983 |
| 18 |
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Horch, Kenneth W.; Tuckett, Robert P.; Burgess, Paul Richard | Neural signal for skin indentation depth. II. Steady indentations | The glabrous skin of the monkey's hand was stimulated with a waveform that indented the skin at a rate of 0.4 mm/set, held the skin steadily or nearly steadily indented for 12 set or longer, and then retracted back to the starting position. Recordings were made of activity in single afferent fibe... | Skin; Indentation; Nerve impulses | 1983 |
| 19 |
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Horch, Kenneth W.; Tuckett, Robert P.; Burgess, Paul Richard | Neural signal for the intensity of a tactile stimulus | The effect of indenting the skin at different rates on the perceived intensity of the stimulus was studied by indenting the skin of the fingertip with two triangular waveforms, given as a pair. The subjects were asked to judge which member of the pair was more intense. Perceived intensity was foun... | Skin; Indentation; Nerve impulses | 1984 |
| 20 |
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Christensen, Douglas A. | Multiple sensor optical thermometry system for application in clinical hyperthermia | The thermometry system described is based upon the temperature dependence of the band edge absorption of infrared light in GaAs crystal. The design of the thermometry was completed, and the system was subjected to an extensive evaluation, including testing with tissue phantoms and microwave applic... | Thermometry; Hyperthermia applicator; Phantom tests | 1984-01 |
| 21 |
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Christensen, Douglas A. | Influence of temperature probe sheathing materials during ultrasonic heating | The influence of sheathing materials upon temperature probes used during the monitoring of ultrasonic heating was measured. The measurements show that the sheathing can be heated in a manner not representative of the temperature rise occurring in the surrounding material, altering the probe reading... | Ultrasonic hyperthermia; Sheathing; Phantom tests; Teflon | 1986-05 |
| 22 |
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Gesteland, Raymond F.; Atkins, John F.; Weiss, Robert B. | Slippery runs, shifty stops, backward steps and forward hops: -2, -1, +1, +2, +5 and +6 Ribosomal frameshifting | Frameshift mutations frequently express residual levels of gene activity; that is, they are often leaky. This leakiness can be used as a tool to define the functional components that affect the reading frame during gene expression. Recent technological advances in the capability to efficiently bu... | Molecular Sequence Data; Mutation; RNA, Transfer; Frameshifting | 1987 |
| 23 |
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Horch, Kenneth W. | Identification of single units in multi-unit recordings from peripheral nerves | We are developing a computer-based method for identifying individual action potentials in multi-unit peripheral nerve recordings. Threshold level, sinusoidal stimuli are used to elicit phase-locked activity from single units. These action potentials are digitized, and a template is constructed usin... | Peripheral nerve; Neural recordings; Cutaneous mechanoreceptors | 1988 |
| 24 |
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Normann, Richard A.; Kolb, Helga | Neural organization of the retina of the turtle Mauremys caspica: a light microscope and Golgi study | The organization of the retina of the turtle species Mauremys caspica, found in fresh water ponds of Israel, has been examined by light microscopical techniques including examination of fresh wholemount retina, one micron blue-stained vertical sections and Golgi-stained material. The anatomical find... | Turtle Retina; Photoreceptors; Golgi Technique; Amarcine Cells | 1988 |
| 25 |
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Horch, Kenneth W.; Normann, Richard A. | Noble metal penetrating cortical stimulating electrode array: preliminary results | Electrical stimulation of the visual cortex causes subjects to see spots of light (phosphenes) in their visual fields. We have developed arrays of penetrating electrodes which may from the basis of a visual prosthesis centered around electrical stimulation of the visual cortex. These arrays have bee... | Visual prosthesis | 1988 |
