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| Creator | Title | Description | Subject | Date | ||
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Couldwell, William T. | Comment on: Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials | The long-term consequences of adenovirus-mediated conditional cytotoxic gene therapy for gliomas remain uncharacterized. We report here detection of active brain inflammation 3 months after successful inhibition of syngeneic glioma growth. The inflammatory infiltrate consisted of activated macrophag... | Brain inflammation; Herpes simplex virus-1; Thymidine kinase; Syngeneic glioma; Adenovirus-mediated gene therapy | 1994 |
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