UScholar Works
 
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1 Kynaston, Baley, Kovtun, Roman, Loveridge, Kade, Nielson, Chris, Brandes, AnnaPlanetary Health Report Card: The University of Utah School of Medicine. 2020-2021Planetary Health; PHRC; Climate Change; Sustainability; Health; Healthcare; Water; Scarcity Food Systems; Urbanization Biodiversity Natural; Disasters Land Use Pollution; Biogeochemical Flows; Global Health; Medical School Education; Curriculum; Research; Outreach; Advocacy; Environmental Justice2020; 2021
2 Adler, Frederick R.Long-term models of oxidative stress and mitochondrial damage in insulin resistance progressionInsulin resistance, characterized by a reduced cellular response to insulin, is a major factor in type 2 diabetes pathogenesis, with a complex etiology consisting of a combination of environmental and genetic factors. Oxidative stress, which develops through an accumulation of toxic reactive oxygen ...2014-01-01
3 LaStayo, Paul C.Resistance exercise with older fallers: Its impact on intermuscular adipose tissueObjective. Greater skeletal muscle fat infiltration occurs with age and contributes to numerous negative health outcomes. The primary purpose was to determine whether intermuscular adipose tissue (IMAT) can be influenced by an exercise intervention and if a greater reduction in IMAT occurs with ecce...2014-01-01
4 Capecchi, Mario R.Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironmentAlveolar soft part sarcoma (ASPS), a deadly soft tissue malignancy with a predilection for adolescents and young adults, associates consistently with t(X;17) translocations that generate the fusion gene ASPSCR1-TFE3. We proved the oncogenic capacity of this fusion gene by driving sarcomagenesis in m...2014-01-01
5 Smith, Ken R.A population-based study of childhood cancer survivors body mass indexPopulation-based studies are needed to estimate the prevalence of underweight or overweight/obese childhood cancer survivors. Procedure. Adult survivors (diagnosed ≤20 years) were identified from the linked Utah Cancer Registry and Utah Population Database. We included survivors currently aged ≥...2014-01-01
6 Hunt, Steven C.Association of egg consumption and calcified atherosclerotic plaque in the coronary arteries: The NHLBI Family Heart StudyBackground and Aims: Eggs are a ubiquitous and important source of dietary cholesterol and nutrients, yet their relationship to coronary heart disease (CHD) remains unclear. While some data have suggested a positive association between egg consumption and CHD, especially among diabetic subjects, lim...2014-01-01
7 LaStayo, Paul C.Intermuscular fat: a review of the consequences and causesMuscle's structural composition is an important factor underlying muscle strength and physical function in older adults. There is an increasing amount of research to support the clear disassociation between the loss of muscle lean tissue mass and strength with aging. This disassociation implies that...2014-01-01
8 Couldwell, William T.Sellar and parasellar metastatic tumorsThe sellar and parasellar (SPS) region is a complex area rich in vital neurovascular structures a first manifestation of a systemic malignancy. Metastases to this region are rare; breast cancer is the most common source among those that metastasize to the SPS region. Ophthalmoplegia, headache, retro...2012-01-01
9 Mower, AllysonExploring publishing patterns at a large research university: Implications for library practiceObjective - The research project sought to explore the value of data on publication patterns for decision-making regarding scholarly communications and collection development programs at a research-intensive post-secondary institution, the University of Utah in the United States. Methods - Publicati...2012-01-01
10 Light, Alan R.Activation of Src family kinases in spinal microglia contributes to formalin-induced persistent pain state through p38 pathwayProtein tyrosine phosphorylation has been implicated in normal and pathological functions, such as cell proliferation, migration and differentiation. Recently, some studies have shown that Src family kinases (SFKs) were involved in neurological disorders and neuropathic pain states in which microgli...2012-01-01
11 Murphy, Patricia A.Extended and continuous combined contraceptive regimens for menstrual suppressionMany women have medical indications for menstrual suppression or a personal preference to reduce or eliminate monthly bleeding, which can be achieved with extended and continuous regimens of combined estrogen and progestin contraceptives. Combined contraceptives are traditionally administered in a 2...2012-01-01
12 Ehleringer, James R. ; Cerling, Thure E.Aberrant water homeostasis detected by stable isotope analysisWhile isotopes are frequently used as tracers in investigations of disease physiology (i.e., 14C labeled glucose), few studies have examined the impact that disease, and disease-related alterations in metabolism, may have on stable isotope ratios at natural abundance levels. The isotopic composition...2010-07-21
13 Kowalski, Christopher Aaron; Deesing, Michole Ann; Deeter, Nicholas B.; Symons, John DavidCeramide-induced disruption of endothelial nitric oxide synthase dimerization in bovine aortic endothelial cells (BAECs) is not secondary to peroxynitrite formationAn estimated 23.6 million individuals in the United States have diabetes and of those 90-95% have type II diabetes. Cardiovascular complications (e.g., hypertension and vascular dysfunction) are four-fold more prevalent in patients with type II diabetes. To gain insight into mechanisms responsib...Ceramide-induced disruption; Nitric oxide synthase dimerization; Bovine aortic endothelial cells; BAEC; Peroxynitrite formation; Trapeze Interactive Poster2010-01-20
14 Symons, John DavidCeramide-induced disruption of endothelial nitric oxide synthase dimerization in bovine aortic endothelial cells (BAECs) is not secondary to peroxynitrite formationAn estimated 23.6 million individuals in the United States have diabetes and of those 90-95% have type II diabetes. Cardiovascular complications (e.g., hypertension and vascular dysfunction) are four-fold more prevalent in patients with type II diabetes.1 The mechanism(s) responsible for increased s...2010-01-01
15 Shaw, Janet M.; Moyer-Mileur, Laurie L.The new glucose revolution: is the authoritative guide to the glycemic index the right dietary solution for lifelong health?The persistence of an epidemic of obesity, coronary heart disease and type 2 diabetes suggests that new nutritional strategies are needed if the epidemic is to be overcome. A promising nutritional approach suggested by this thematic review is carbohydrate restriction. Under conditions of carbohydra...2010
16 Churchwell, John C.; Lopez-Larson, Melissa; Yurgelun-Todd, Deborah A.Altered frontal cortical volume and decision making in adolescent cannabis usersAnticipating future outcomes is central to decision making and a failure to consider long-term consequences may lead to impulsive choices. Adolescence is a vulnerable period during which underdeveloped prefrontal cortical systems may contribute to poor judgment, impulsive choices, and substance ab...2010
17 Couldwell, William T.Metabolic syndrome: what neurosurgeons should knowThe term metabolic syndrome, first introduced in 1988, has evolved in concept since that time. While the strict definition is subject to ongoing debate, the syndrome generally involves glucose intolerance, obesity, dyslipidemia and high blood pressure, which increase the risk of developing cardiovas...2008-01-01
18 Owen, William E.; Roberts, William L.Effects of hemoglobin (Hb) E and HbD traits on measurements of glycated Hb (HbA1c) by 23 methods.Glycohemoglobin (GHB), reported as hemoglobin (Hb) A1c, is a marker of long-term glycemic control in patients with diabetes and is directly related to risk for diabetic complications. HbE and HbDare the second and fourth most common Hb variants worldwide. We investigated the accuracy of HbA1c measur...Glycohemoglobin; GHB; Glycated Hb; Glycemic control2008
19 Cashdan, Elizabeth A.Waist-to-hip ratio across cultures: trade-offs between androgen- and estrogen-dependent traitsA gynoid pattern of fat distribution, with small waist and large hips (low waist-to-hip ratio, or WHR) holds significant fitness benefits for women: women with a low WHR of about 0.7 are more fecund, are less prone to chronic disease, and (in most cultures) are considered more attractive. Why, then...Fat distribution; Gynoid pattern; Body types; Waist-to-hip ratio; WHR2008
20 Agarwal, NiveditaBrain function monitoring during off-pump cardiac surgery: a case reportBackground: Early postoperative stroke is an adverse syndrome after coronary bypass surgery. This report focuses on overcoming of cerebral ischemia as a result of haemodynamic instability during heart enucleation in off-pump procedure. Case presentation: A 67 year old male patient, Caucasian race, ...2008
21 Cashdan, Elizabeth A.Waist-to hip ratio across cultures: trade-offs between androgen-and estrogen-dependent traitsA gynoid pattern of fat distribution, with small waist and large hips (low waist-to-hip ratio, or WHR) holds significant fitness benefits for women: women with a low WHR of about 0.7 are more fecund, are less prone to chronic disease, and (in most cultures) are considered more attractive. Why, then...Fertility; Optimum; Fecundity2008
22 Digre, Kathleen B.Serum vitamin A concentration is elevated in idiopathic intracranial hypertension.OBJECTIVE: The primary purpose was to investigate whether serum vitamin A concentration is associated with idiopathic intracranial hypertension (IIH). The secondary aim was to obtain pilot data regarding the amount of vitamin A ingested by patients and controls. BACKGROUND: Vitamin A is an attractiv...Vitamin A; Retinol; Idiopathic intracranial hypertension; Chromatography2007-02-01
23 Couldwell, William T.; Nelson, Don HarryNelson syndrome: historical perspectives and current conceptsThe appearance of an adrenocorticotropic hormone (ACTH)-producing tumor after bilateral adrenalectomy for Cushing disease was first described by Nelson in 1958. The syndrome that now bears his name was characterized by hyperpigmentation, a sellar mass, and increased plasma ACTH levels. The treatment...2007-01-01
24 Askew, Eldon W.; Bernstein, Paul S.Serum and macular responses to antioxidant supplementation verus a carotenoid-rich dietary intervention in the elderly.The aim of this study was to observe responses of serum antioxidants, oxidative stress biomarkers, and macular carotenoid pigments to antioxidant supplements or dietary intervention in a single-masked, randomized, pilot clinical study of elderly subjects receiving antioxidant supplements or a dietar...Macula; Serum Carotenoids; Zeaxanthin2006-02-01
25 Sung, Younghoon; Renshaw, Perry FranklinPrefrontal grey-matter changes in short-term and long-term abstinent methamphetamine abusersAuthor's explored grey-matter density in 29 methamphetamine abusers and 20 healthy comparison subjects using voxel-based morphometry. Grey-matter density changes and performances on the Wisconsin Card Sorting test (WCST) were also compared between 11 short-term (<6 months) and 18 long-term (o6 mon...2006
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