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CreatorTitleDescriptionSubjectDate
76 Burton, CharlesBiomedical Instrumentation in the Soviet UnionBiomedical Informatics1977
77 Erickson, J. Alan; Smith, Jeffrey, J.; Bornhorst, Joshua A.; Ashwood, Edward R.Humananti-mouse antibody protected ELISA for the quantification of squamous cell carcinoma antigenSquamous cell carcinoma antigen (SCC) was first isolated from squamous cell carcinoma tissue of the uterine cervix and initially reported as TA-4. The antigen has been characterized as a glycoprotein with a molecular weight between 45,000 and 55,000 daltons. Studies suggest that SCC may function as ...SCC; Squamous Cell Carcinoma Antigen; BSA; PBS; Phosphate Buffered Saline; HAMA; Human Anti-mouse Antibodies; IIR; ImmunoglobulinInhibiting Reagent2005-12-09
78 Seger, JonEvolution of individuality by Leo W. BussMetazoans seldom reproduce vegetatively; they often die of cancer; and they almost always sequester their germ lines. Plants often reproduce vegetatively, seldom die of cancer, and almost never sequester a germ line. Buss argues that these and many other patterns can all be understood in a unified w...Cell lines; Hierarchy; Biology1988
79 Couldwell, William T.; Viskochil, David H.; Fults, Daniel WebsterMolecular, genetic, and cellular pathogenesis of neurofibromas and surgical implicationsNEUROFIBROMATOSIS 1 (NF1) IS A common autosomal dominant disease characterized by complex and multicellular neurofibroma tumors. Significant advances have been made in the research of the cellular, genetic, and molecular biology of NF1. The NF1 gene was identified by positional cloning. The function...Loss of heterozygosity; Malignant peripheral nerve sheath tumor; Plexiform Neurofibroma; Spinal neurofibroma2006
80 Jorde, Lynn B.Clinical and biochemical function of polymorphic NR0B1 GGAA-microsatellites in Ewing sarcoma: A report from the Childrens Oncology GroupBackground: The genetics involved in Ewing sarcoma susceptibility and prognosis are poorly understood. EWS/FLI and related EWS/ETS chimeras upregulate numerous gene targets via promoter-based GGAA-microsatellite response elements. These microsatellites are highly polymorphic in humans, and prelimina...2014-01-01
81 Couldwell, William T.Metastatic melanoma to the pituitary glandMetastasis to the pituitary gland is unusual, and occurs most often in patients with carcinomas of the breast or lung. Despite its propensity for spread to the brain, metastatic melanoma has rarely been described within the sella. Methods: We report two cases of malignant melanoma pathologically co...2007
82 Couldwell, William T.Clinical and radiographic response in a minority of patients with recurrent malignant gliomas treated with high-dose tamoxifenPREVIOUS WORK HAS demonstrated the importance of the Protein Kinase C (PKC) signal transduction system in regulating the growth rate of malignant gliomas in vitro. Tamoxifen inhibits PKC in a minority of malignant gliomas within the micromolar concentration range in vitro, a property distinct from...Tamoxifen; Protein kinase C; Glioma; Brain neoplasm; Chemotherapy; Glioma1993
83 Yaffe, JoanneEmpty reviews: a description and consideration of cochrane systematic reviews with no included studiesBackground: There is no specific guidance for the reporting of Cochrane systematic reviews that do not have studies eligible for inclusion. As a result, the reporting of these so-called ‘‘empty reviews'' may vary across reviews. This research explores the incidence of empty systematic reviews in...2012-01-01
84 Anderson, Kasey L.Drug release profile for an ETS-1 inhibitor in ReGel2013-08-01
85 Christensen, Douglas A.Resonant inductive applicator for neck hyperthermiaWe have designed and phantom tested an inductive applicator especially suited for producing hyperthermia in cancerous regions in the neck. The applicator is tuned to resonate near 27 MHz; its inductive nature has the advantage of efficient coupling to the irregular neck anatomy. An inhomogeneou...Hyperthermia applicator; Phantom tests1989
86 Gardner, Reed M.Medical Informatics at the University of Utah: Applying Research to Real-Life IssuesBiomedical Informatics1999
87 Kestle, John R. W.; Brockmeyer, Douglas LeeEvaluation of the necessity of postoperative imaging after craniosynostosis surgeryObject. Childhood radiation exposure increases the lifetime risk of cancer from an estimated 0.07 to 0.35%. Neurological evaluation of patients after cranial vault reconstruction for synostosis repair is often complicated by pain medication, sedation, intubation, swelling, and dressings; therefore c...Computed tomography; Cranial vault reconstruction; Pediatric neurosurgery; Radiation dose; Postoperative imaging2007
88 Coley, Phyllis D.New cytotoxic cinnamic acid derivatives from leaves of Bonamia trichanthaBioassay-guided fractionation of the methanolic extract of the young leaves of Bonamia trichantha led to the isolation of four new cinnamic acid derivatives trichanthins A-D (l-4).Their structures were established by spectroscopic methods. All compounds were tested in cytotoxic assays against the MC...Bonamia trichantha; Cinnamic acid; Caffeic acid ester; p-Coumaric acid ester: Farnesol; Z-(l l)-hexadecen-l-ol; Cytotoxicity2006
89 Huang, Lin EricHIF-1? mediates tumor hypoxia to confer a perpetual mesenchymal phenotype for malignant progressionAlthough tumor progression involves genetic and epigenetic alterations to normal cellular biology, the underlying mechanisms of these changes remain obscure. Numerous studies have shown that hypoxia-inducible factor 1? (HIF-1?) is overexpressed in many human cancers and up-regulates a host of hypoxi...
90 Moon, Anne M.TBX3 regulates splicing in vivo: a novel molecular mechanism for Ulnar-Mammary SyndromeTBX3 is a member of the T-box family of transcription factors with critical roles in development, oncogenesis, cell fate, and tissue homeostasis. TBX3 mutations in humans cause complex congenital malformations and Ulnar-mammary syndrome. Previous investigations into TBX3 function focused on its acti...2014-01-01
91 Garber, SarahImage guidance for brain metastases resectionThe primary goal in removing a metastatic brain tumor is to maximize surgical resection while minimizing the risk of neurological injury. Intraoperative image guidance is frequently used in the resection of both primary and metastatic brain tumors. Stereotactic volumetric techniques allow for smalle...2012-01-01
92 Coley, Phyllis D.; Kursar, Thomas A.Using ecological criteria to design plant collection strategies for drug discoveryTropical forests are one of the most diverse and endangered habitats on earth. They have also been portrayed as a source of future pharmaceuticals, yet finding useful compounds can be both scientifically and politically challenging. Increasingly, over the past decade, the potential value of medicina...Drug discovery; Biodiversity2003
93 Slev, Patricia R.; Rawlins, Mindy, L.; Roberts, William L.Performance characteristics of seven automated CA 15-3 methodsPoster describing studies to evaluate seven automated methods for the following parameters: limit of detection, linearity, imprecision, reference intervals and method comparison with the ADVIA Centaur as the comparison method to detect CA 15-3.CA 15-3 Method2005-07-13
94 Battin, Margaret P.Case comment: the case of Nicole: suicide and terminal illnessWhat shall one say about Nicole? My immediate answer is an easy one-liner: if there ever were a case in which a choice of suicide appears both rational and rationally made, this seems to be it.1933
95 Battin, Margaret P.Nicole: suicide and terminal illnessThe terminally ill person who plans suicide poses a clinical dilemma in suicidology. Issues of rational suicide are complicated. Although experts (Battin, 1991; Hoff, 1989; Motto, 1972; Pretzel, 1984; Saunders & Valente, 1988) recognize rational suicide, the prevailing paradigm of suicide preventio...Terminal illness; Suicidology1993
96 Mineau, Geraldine PageFamilial predisposition to developmental dysplasia of the hipDevelopmental dysplasia of the hip (DDH) is a common birth defect and is thought to have genetic contributions to the phenotype. It is likely that DDH is genetically heterogeneous with environmental modifiers. The Utah Population Database (UPDB) is a computerized integration of pedigrees, vital stat...Developmental dysplasia of the hip; DDH; Utah Population Database; UPDB2009
97 Smith, Ken R.; Waitzman, Norman J.Double jeopardy: interaction effects of marital and poverty status on the risk of mortalityThe purpose of this paper is to examine the hypothesis that marital and poverty status interact in their effects on mortality risks beyond their main effects. This study examines the epidemiological bases for applying an additive rather than a multiplicative specification when testing for interacti...National Health and Nutrition Examination Survey1994
98 Battin, Margaret P.Review of euthanasia and law in EuropeEuthanasia and Law in Europe is an examination of physician-assisted dying or physician performed euthanasia and the laws concerning these practices in European jurisdictions where the issue has been most visible. The Author's focus primarily on the Netherlands, where the practice has been open si...2009
99 Capecchi, Mario R.Modeling alveolar soft part sarcomagenesis in the mouse: a role for lactate in the tumor microenvironmentAlveolar soft part sarcoma (ASPS), a deadly soft tissue malignancy with a predilection for adolescents and young adults, associates consistently with t(X;17) translocations that generate the fusion gene ASPSCR1-TFE3. We proved the oncogenic capacity of this fusion gene by driving sarcomagenesis in m...2014-01-01
100 Couldwell, William T.Pituitary modelsPituitary tumor animal models provide researchers a microenvironment that simulates the clinical situation; however, in comparison with astrocytoma and meningioma tumor research where intracranial xenograft transplantations are increasingly being used to test various therapeutic modalities, in vivo ...2013-01-01
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