|
|
Creator | Title | Description | Subject | Date |
526 |
|
Couldwell, William T.; Nelson, Don Harry | Nelson syndrome: historical perspectives and current concepts | The appearance of an adrenocorticotropic hormone (ACTH)-producing tumor after bilateral adrenalectomy for Cushing disease was first described by Nelson in 1958. The syndrome that now bears his name was characterized by hyperpigmentation, a sellar mass, and increased plasma ACTH levels. The treatment... | | 2007-01-01 |
527 |
|
Olivera, Baldomero M.; Gray, William Robert; McIntosh, J. Michael | New α-conotoxin which targets α3ß2 nicotinic acetylcholine receptors | We have isolated a 16-amino acid peptide from the venom of the marine snail Conus magus which potently blocks nicotinic acetylcholine receptors (nAChRs) composed of α3ß2 subunits. This peptide, named a-conotoxin MII, was identified by electrophysiologically screening venom fractions against cl... | Conotoxins; a-conotoxin MII; Conus magus | 1996 |
528 |
|
Francis, John G.; Francis, Leslie P. | Rationing of health care in Britain: an ethical critique of public policy-making | IN BRITAIN, as in the United States, rationing of health care is a fact of life and death. Some rationing is overt, such as the Stanford heart transplant program's decision not to accept very young or older patients.1 Some is disguised, such as day-to-day decisions in hospitals about "do not resusci... | Rationing; National Health Service | 1986 |
529 |
|
Couldwell, William T. | Response to Craniopharyngioma adherence to the hypothalamus | To The Editor: We have viewed with great interest the special supplement published by Neurosurgical Focus in January 2013 (Neurosurgical Focus, Video Atlas of Operative Surgery: Intraventricular Lesions: Microscopic and Endoscopic Approaches, Vol 34: January 2013) in which a compilation of videos de... | | 2014-01-01 |
530 |
|
Petti, Cathy A. | Role of the laboratory in diagnosis of influenza during seasonal epidemics and potential pandemics | Laboratory diagnosis of influenza is critical to its treatment and surveillance. With the emergence of novel and highly pathogenic avian influenza viruses, the role of the laboratory has been further extended to include isolation and subtyping of the virus to monitor its appearance and facilitate ap... | Antibodies, Viral; Antigens, Viral; RNA, Viral | 2006 |
531 |
|
Warner, Homer R. | Routine vs. Priority Procedures: Challenging the Medical Checkup | Biomedical Informatics | | 1970 |
532 |
|
Capecchi, Mario R. | Yeast super-suppressors are altered tRNAs capable of translating a nonsense codon in vitro. | tRNA isolated from two different yeast super-suppressor strains translates a known nonsense mutation in vitro, whereas tRNA from a closely related nonsuppressing strain does not. Suppression was assayed by translation of RNA isolated from an amber coat mutant of bacteriophage Qbeta (GB11) in a prote... | Codon; Escherichia coli; Protein Biosynthesis | 1975-11 |
533 |
|
Poulter, Charles Dale; Davis, Darrell R. | 15N labeled e. coli tRNAMet, tRNAGlu, tRNATyr, and tRNAPhe. Double resonance and two dimensional NMR of H-N1 units in pseudouridine | The N1 imino units in Escherichia coli tRNAfMet, tRNAGlu, tRNAPhe, and tRNATyr were studied by 1H-15N NMR using three different techniques to suppress signals of protons not attached to 15N. Two of the procedures, Fourier internuclear difference spectroscopy and two-dimensional forbidden echo spectr... | Escherichia coli; Magnetic resonance spectroscopy; Nucleic acid conformation | 1985-08-15 |
534 |
|
Marcus, Robin | An eccentrically biased rehabilitation program early after TKA surgery | Rehabilitation services are less-studied aspects of the management following total knee arthroplasty (TKA) despite long-term suboptimal physical functioning and chronic deficits in muscle function. This paper describes the preliminary findings of a six-week (12 session) eccentrically-biased rehabili... | | 2011 |
535 |
|
Hendee, Shonn P.; Faour, Fouad A.; Christensen, Douglas A.; Patrick, Baharah; Durney, Carl H.; Blumenthal, Donald K. | Effects of weak extremely low frequency magnetic fields on calcium/calmodulin interactions. | Mechanisms by which weak electromagnetic fields may affect biological systems are of current interest because of their potential health effects. Lednev has proposed an ion parametric resonance hypothesis (Lednev, 1991, Bioelectromagnetics, 12:71-75), which predicts that when the ac, frequency of a c... | Electromagnetic Fields; Calcium-binding Proteins; Lednev's Theory | 1996-06 |
536 |
|
Coley, Phyllis D.; Kursar, Thomas A. | Effects of weather on fungal abundance and richness among 25 communities in the Intermountain West | Because moisture and temperature influence the growth of fungi, characterizing weather conditions favorable for fungi may be used to predict the abundance and richness of fungi in habitats with different climate conditions. To estimate habitat favorability to fungi, we examined the relationship of f... | Intermountain West; Utah; Microclimate; Fungal prevalence | 2002 |
537 |
|
Baehr, Wolfgang | Identification and light-dependent translocation of a cone-specific antigen, (Cone Arrestin) recognized by monoclonal antibody 7G6 | PURPOSE: To elucidate the antigen recognized by monoclonal antibody (mAb) 7G6, a widely used cone-specific marker. METHODS: 7G6 immunocytochemistry was performed on sections of human, primate, and bovine retina. The antigen was immunoprecipitated from human retinal lysates and purified with protein ... | Cones (Retina); Molecular Sequence Data; Phototransduction | 2003 |
538 |
|
Olivera, Baldomero M. | Nicotinic acetylcholine receptor ligand of unique specificity, α-conotoxin ImI | We report the isolation, characterization, and total synthesis of a small peptide ligand for nicotinic acetylcholine receptors (nAChRs). It is highly active against the neuromuscular receptor in frog but noitn mice. In contrast, it induces seizures when injected centrally in mice and rats, suggesti... | Conotoxins; a-conotoxin ImI | 1994 |
539 |
|
Zhang, Kang | Spectrum and frequency of FZD4 mutations in familial exudative vitreoretinopathy | Mutations in the frizzled-4 gene (FZD4) have recently been associated with autosomal dominant familial exudative vitreoretinopathy (FEVR) in families linking to the EVR1 locus on the long arm of chromosome 11. The purpose of this study was to screen FZD4 in a panel of 40 patients with FEVR to ident... | Frizzled-4 gene; FZD4; Mutation; autosomal dominant familial exudative autosomal dominant familial exudative; FEVR | 2004 |
540 |
|
Capecchi, Mario R. | Targeted disruption of the even-skipped gene, evx1, causes early postimplantation lethality of the mouse conceptus. | Implantation within the mammalian uterus elicits dramatic changes in the growth, differentiation, and morphogenesis of the conceptus. This process is interrupted in mice carrying a targeted disruption of the murine evx1 gene, a homolog of the Drosophila even-skipped (eve) gene. Upon implantation, pr... | Extraembryonic; Homozygotes; Drosophila | 1994-08-15 |
541 |
|
Gerig, Guido | Unbiased diffeomorphic atlas construction for computational anatomy | Construction of population atlases is a key issue in medical image analysis, and particularly in brain mapping. Large sets of images are mapped into a common coordinate system to study intra-population variability and inter-population differences, to provide voxel-wise mapping of functional sites, a... | | 2004-01-01 |
542 |
|
Poulter, Charles Dale; Davis, Darrell R. | 15N-labeled Escherichia coli tRNAfMet, tRNAGlu, tRNATyr, and tRNAPhe. Double resonance and two-dimensional NMR of N1-labeled pseudouridine. | The N1 imino units in Escherichia coli tRNAfMet, tRNAGlu, tRNAPhe, and tRNATyr were studied by 1H-15N NMR using three different techniques to suppress signals of protons not attached to 15N. Two of the procedures, Fourier internuclear difference spectroscopy and two-dimensional forbidden echo spectr... | Escherichia coli; Magnetic resonance spectroscopy; Nitrogen; Nucleic acid conformation | 1985-08-15 |
543 |
|
Adler, Frederick R. | Alternating host cell tropism shapes the persistence, evolution and coexistence of Epstein-Barr virus infections in human | Epstein-Barr virus (EBV) infects and can persist in a majority of people worldwide. Within an infected host, EBV targets two major cell types, B cells and epithelial cells, and viruses emerging from one cell type preferentially infect the other. We use mathematical models to understand why EBV infec... | | 2011 |
544 |
|
Adler, Frederick R. | Alternating host cell tropism shapes the persistence, evolution and coexistence of Epstein-Barr virus infections in human | Epstein-Barr virus (EBV) infects and can persist in a majority of people worldwide. Within an infected host, EBV targets two major cell types, B cells and epithelial cells, and viruses emerging from one cell type preferentially infect the other. We use mathematical models to understand why EBV infec... | | 2010 |
545 |
|
Battin, Margaret P. | Assisted suicide: can we learn from Germany? | As the United States' public discussion of euthanasia and assisted suicide grows increasingly volatile, our interest in the Netherlands--the only country that openly permits the practice of euthanasia--has grown enormously. How do they do it? we ask. What drugs do they use? How many cases of euthan... | Assisted suicide; Netherlands; Right to die | 1992 |
546 |
|
Zimmer, Zachary | Education of adult children and mortality of their elderly parents in Taiwan | Research shows an older adult's education is strongly associated with mortality. But in societies such as Taiwan, where families are highly integrated, the education of family members may be linked to survival. Such may be the case in settings where there are large gaps in levels of education acros... | Education; Mortality | 2005 |
547 |
|
Jorgensen, Erik | Function and misfunction of the two promoters of the Drosophila Antennapedia gene | In the Antennapedia (Antp) gene of Drosophila melanogaster, structurally distinct RNAs arise from different transcription initiation sites. When the two sites are separated by a chromosome inversion, transcripts are produced from each fragment of the split Antp locus, and these RNAs initiate at the ... | RNA; Antp; Hybridization | 1987 |
548 |
|
Mitchell, Joyce A. | Fuzzy measures on the Gene Ontology for gene product similarity | One of the most important objects in bioinformatics is a gene product (protein or RNA). For many gene products, functional information is summarized in a set of Gene Ontology (GO) annotations. For these genes, it is reasonable to include similarity measures based on the terms found in the GO or othe... | | 2006-01-01 |
549 |
|
Dailey, Andrew T. | Guidelines for the performance of fusion procedures for degenerative disease of the lumbar spine. Part 13: injection therapies, low-back pain, and lumbar fusion | Standards. Facet injections are not recommended as long-term treatment for chronic low-back pain. Guidelines. There is insufficient evidence to recommend a treatment guideline. Options. The use of lumbar epidural injections or TPIs is not recommended as a treatment option for long-term relief of c... | Fusion procedures; Degenerative disease; Lumbar spine; Injection therapies; Low-back pain; Lumbar fusion | 2005 |
550 |
|
Capecchi, Mario R. | Hoxc13 mutant mice lack external hair | Hox genes are usually expressed temporally and spatially in a colinear manner with respect to their positions in the Hox complex. Consistent with the expected pattern for a paralogous group 13 member, early embryonic Hoxc13 expression is found in the nails and tail. Hoxc13 is also expressed in vibri... | Filiform papillae; Homozygotes; Paralogous | 1998-01-01 |