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Creator | Title | Description | Subject | Date |
451 |
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Olivera, Baldomero M. | Alternative splicing in the pore-forming region of shaker potassium channels | We have cloned cDNAs for the shaker potassium channel gene from the spiny lobster Panulirus interruptus. As previously found in Drosophila, there is alternative splicing at the 59 and 39 ends of the coding region. However, in Panulirus shaker, alternative splicing also occurs within the pore-forming... | Panulirus interruptus; Conotoxins; Shaker; Stomatogastric ganglion; Pore-forming region; Alternative splicing | 1997 |
452 |
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Firmage, Edwin B. | Religion & the law: the Mormon experience in the nineteenth century | The Mormon cases present a fascinating study of diversity and conformity in the nineteenth century United States. From their beginning the Mormons were a gathered people. Almost immediately, from the time of the origin in New York, the Mormons challenged national and state legal systems to protect... | Law; Church of Jesus Christ of Latter Day Saints; Nineteenth century; Polygamy; Theocracy | 1990 |
453 |
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Mattis, Daniel C. | A contribution to the many-fermion problem | In this work we reexamine the many-fermion problem in arbitrary dimensions. It is shown that in two dimensions or higher, the Hamiltonian of interacting fermions can be separated into individual nonintersecting sectors labeled by the wave-vector q. Within each sector the Hamiltonian maps onto a gene... | | 2012-01-01 |
454 |
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Horch, Kenneth W. | Acoustic interneurons of fiddler and ghost crabs | The properties of acoustic interneurons in fiddler (Uca pugilalor and U. minax) and ghost (Ocvpade qucldrula) crabs are described, as revealed bv tests with pure tones. Three types of interneurons were present in all species: tonic, which fired for the duration of the stimulus; phasic, which fire... | Acoustic crabs; Neural recording; Vibration reception | 1976 |
455 |
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McDaniel, Susan | Explaining Canadian fertility: some remaining challenges | Canada is in an advantageous position to study the social context of human reproduction and childbearing. Canadian contributions to the fertility literature have thus far been impressive. In spite of the obvious solid base of fertility research in Canada, some challenges remain. Among these are cap... | Economic; Canada; Research | 1984 |
456 |
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Plutynski, Anya | Explanation in classical population genetics | The recent literature in Philosophy; of biology has drawn attention to the different sorts of explanations proffered in the biological sciences--we have molecular, biomedical, and evolutionary explanations. Do these explanations all have a common structure or relation that they seek to capture? This... | Biology, Philosophy;; Explanation; Genetics; Life sciences; Population genetics; Science | 2005-12 |
457 |
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Brinkman, Paul T. | Factors affecting instructional costs at major research universities | The purpose of this article is to analyze in quantitative terms why unit instructional costs differ among major research universities. Previous studies have uncovered many of the factors that account for costs in higher education. The primary task here is to specify the relative importance of thes... | Research universities; Costs; Instruction | 1981 |
458 |
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Riloff, Ellen M. | Feature subsumption for opinion analysis | Lexical features are key to many approaches to sentiment analysis and opinion detection. A variety of representations have been used, including single words, multi-word Ngrams, phrases, and lexicosyntactic patterns. In this paper, we use a subsumption hierarchy to formally define different types o... | Feature subsumption; Sentiment analysis; Opinion detection; Subsumption hierarchy | 2006 |
459 |
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Thomas, Kirk R.; Capecchi, Mario R. | Introduction of homologous DNA sequences into mammalian cells induces mutations in the cognate gene. | Injection of homologous DNA sequences into nuclei of cultured mammalian cells induces mutations in the cognate chromosomal gene. It appears that these mutations result from incorrect repair of a heteroduplex formed between the introduced and the chromosomal sequence. This phenomenon is termed 'heter... | Animals; Cell Line; Drug Resistance, Microbial; Fibroblasts; Mice; Models, Genetic; Neomycin; Plasmids | 1986-11-06 |
460 |
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Rogers, Alan R.; Harpending, Henry C. | Mismatch distributions of mtDNA reveal recent human population expansions | Although many genetic studies of human evolution have tried to make distinctions between the replacement and the multiregional evolution hypotheses, current methods and data have not resolved the issue. However, new advances in nucleotide divergence theory can complement these investigations with a ... | | 1994 |
461 |
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O'Rourke, Dennis H. | Patterns of genetic variation in native America | Allele frequencies from seven polymorphic red cell antigen loci (ABO, Rh, MN, S, P, Duffy, and Diego) were examined in 144 Native American populations. Mean genetic distances (Nei's D) and the fixation index FST are approximately equal for the North and South American samples but are reduced in the... | Gene frequencies; Amerinds; Genetic Distance | 1992 |
462 |
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Capecchi, Mario R.; Thomas, Kirk R. | Swaying is a mutant allele of the proto-oncogene Wnt-1 | Mice homozygous for the recessive mutation swaying (SW) are characterized by ataxia and hypertonia, attributed to the malformation of anterior regions of the cerebellum. We show that SW is a deletion of a single base pair from the proto-oncogene Wnf-1. The deletion is predicted to cause premature t... | Swaying allele; protooncogene Wnt-1; Mutant genes; Mutant alleles | 1991 |
463 |
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Flynn, John J. | Social, political and economic consequences of corporate size | Congress has often expressed its concern for fostering the long term values of small business as the cornerstone of a viable political, social and economic system guaranteeing fundamental human freedom, maximizing economic opportunity and well-being, and providing political stability in the world's... | Small business; Freedom; Congress | 1976 |
464 |
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Carrier, David R. | Functional tradeoffs in specialization for fighting versus running | Both locomotion and fighting are critical to survival and reproductive fitness in many vertebrate species. Yet, characters that make an individual good at fighting may, in many cases, limit locomotor performance and vice versa. Here I describe tests of three functional tradeoffs in the limb muscles ... | Greyhounds; Pit Bulls; Australopithecus; Homo; Fighting; Running; Male-male aggression; Limb muscles; Functional tradeoff | 2002 |
465 |
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Coley, Phyllis D. | Beneficios y costos de defensa en un arbusto del neotrópico | LOS beneficios y costos son de importancia capital para las teorfas de optimization de las defensas de las plantas. El beneficio es la ganancia de aptitud para reducir el herbivorismo; el costo es la perdida de aptitud al comprometer recursos en defensa. Evaluamos los beneficios y los costos de def... | Psychotria horizontalis; Isla de Barro Colorado; Costos de defense; Celdas de exclusion; Herbivorismo; Defensa de las plantas; Taninos; Dureza; Tropicos; Benefit; Beneficios | 2007 |
466 |
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Newton, Maria | Effects of a classroom-based physical activity program on childrens physical activity levels | High levels of physical inactivity are evident among many American children. To address this problem, providing physical activity (PA) during the school day within the CSPAP framework, is one strategy to increase children's PA. Thus, the purpose of this study was to examine the effects of a classroo... | | 2014-01-01 |
467 |
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Lepreau, Jay | DRAFT: work in progress - - - comments solicited evolving Mach 3.0 to use migrating threads | Like most operating systems, Mach 3.0 views threads as statically associated with a single task. An alternative model is that of migrating threads, in which a single thread abstraction moves between tasks with the logical flow of control, and "server" code is passively executed. We have compatibly r... | DRAFT | 1993 |
468 |
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Parker, Bradley J. | Archaeological manifestations of empire: Assyrias imprint on Southeastern Anatolia | One of the most enduring problems for the study of ancient empires is the fact that material correlates indicative of imperial integration are often difficult to define in the archaeological record. This situation results in part from two factors that distinguish empires from other less complex poli... | | 2003-01-01 |
469 |
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Beckerle, Mary C. | Members of the zyxin family of LIM proteins interact with members of the p130cas family of signal transducers | Integrin binding to extracellular matrix proteins induces formation of signaling complexes at focal adhesions. Zyxin co-localizes with integrins at sites of cellsubstratum adhesion and is postulated to serve as a docking site for the assembly of multimeric protein complexes involved in regulating ce... | Zyxin; Actin; LIM domains; Trip6; Focal adhesions | 2002 |
470 |
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Beckerle, Mary C. | Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains | Drosophila Enabled (Ena) was initially identified as a dominant genetic suppressor of mutations in the Abelson tyrosine kinase and, more recently, as a member of the Ena/human vasodilator-stimulated phosphoprotein (VASP) family of proteins. We have used genetic, biochemical, and cell biological appr... | Drosophila Ena; VASP | 1998 |
471 |
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Clark, James Henry | 3-D Design of free-form B-Spline surfaces (CSTD-74-005) | This report describes an experimental system for designing free-form B-spline surfaces using a head-mounted display. In this system, the interaction with the surfaces takes place in three dimensions as the designed object's shape Is updated in real-time. The report also examines some of the problems... | Computer animation | 1974-09 |
472 |
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Beckerle, Mary C. | Zyxin and cCRP: Two interactive LIM domain proteins associated with the cytoskeleton | Interaction with extracellular matrix can trigger a variety of responses by cells including changes in specific gene expression and cell differentiation. The mechanism by which cell surface events are coupled to the transcriptional machinery is not understood, however, proteins localized at sites o... | Zyxin; Cysteine-rich proteins; cCRP; LIM domain | 1992 |
473 |
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Silverman, Randall H. | Book repair in the U.S.A.: a library-wide approach to conservation | Abstract: Modern research library collections are a composite of both rare and non-rare books the majority of which are out of print and irreplaceable. Consequently, conservation treatment priorities cannot responsibly ignore non-rare material without shortchanging future scholarly needs. To address... | Preservation, books; Conservation, books | 1997 |
474 |
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Thomas, Kirk R.; Capecchi, Mario R. | Maintenance of functional equivalence during paralogous Hox gene evolution. | Biological diversity is driven mainly by gene duplication followed by mutation and selection. This divergence in either regulatory or protein-coding sequences can result in quite different biological functions for even closely related genes. This concept is exemplified by the mammalian Hox gene comp... | Alleles; Animals; Cervical Vertebrae; Embryo; Genetic Complementation Test; Homeodomain Proteins; Homozygote; Mice | 2000-02-10 |
475 |
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Hartmann, Donald P. | Considerations in the choice of interobserver reliability estimates | Two types of interobserver reliability values may be needed in treatment studies in which observers constitute the primary data-acquisition system: trial reilability and the reliability of the composite unit or score which is subsequently analyzed, e.g., daily or weekly session totals. Two approache... | Observational technology; Reliability; Validity; Statistics; Recording and measurement techniques; Cohen's kappa; Generalizability theory; Measurement theory; Spearman-Brown prophesy formula; Correlational measures | 1977 |