UScholar Works
 
Filters: Collection: "ir_uspace"
426 - 450 of 625
Number of results to display per page
CreatorTitleDescriptionSubjectDate
426 Parkinson, John StansfieldHAMP domain structural determinants for signalling and sensory adaptation in Tsr, the E. coli serine chemoreceptorMotile Escherichia coli cells track chemical gradients with high sensitivity over wide concentration ranges [recently reviewed in (Hazelbauer et al., 2008; Hazelbauer & Lai, 2010)]. Stimulus detection, amplification, and integration occur in an arrayed network of signaling complexes that contain tra...2014-01-01
427 Planelles, VicenteMethod for obtaining an enriched population of sirna-expressing cellsProblems with transience of siRNA-mediated knock-down and transfection efficiency have limited the scope of RNAi-based experiments. The invention provides a tool for employing RNAi more efficiently and effectively by integrating RNAi expression with methods of cell enrichment.2010
428 Digre, Kathleen B.; Skuster, Denise Z.Neurologic conditions presenting as psychiatric disorders.Understanding underlying neuroanatomic function helps physicians to localize defects and search for treatable neurologic conditions. Neurologic conditions such as Huntington's chorea, Wilson's disease, Gille de la Tourette syndrome, brain tumors, encephalitis and meningitis, neurodegenerative condit...Psychiatric Diagnosis; Neurologic Disease1992-06-15
429 Utz, Rebecca L.Obesity in America, 1960-2000: is it an age, period or cohort phenomenon?Increasing rates of obesity have sparked tremendous public concern because excess body weight is linked to a host of mortality, morbidity, and disability outcomes. Using five waves of data from the National Health and Nutrition Examination Survey (NHANES), this project privides a four-decade pict...Health, weight; Overweight; Population trends2004-09-23
430 Capecchi, Mario R.Characterization of three proteins involved in polypeptide chain termination.At each stage of elongation, the growing polypeptide chain is bound to the ribosome-messenger RNA complex through the transfer RNA of the most recently incorporated amino acid residue. When the chain is complete, the last polypeptide-transfer RNA (tuna) ester linkage is cleaved, releasing the chain ...Anti-Bacterial Agents; Phenylalanine; Stimulation, Chemical1969
431 Kestle, John R. W.Comparison between magnetic resonance imaging and computed tomography for stereotactic coordinate determinationThe spatial accuracy of magnetic resonance imaging (MRI) has not been established for stereotactic surgery. Magnetic susceptibility artifacts may lead to anatomical distortion and inaccurate stereotactic MRI coordinates, especially when targets are in regions of the brain out of the center of the ma...Computed tomography; Stereotactic coordinates; Stereotactic surgery1992
432 Edelman, Linda S.Dangerous spaces: Using geographic information systems in injury researchPURPOSE: To provide an overview of geographic information systems (GIS) and to discuss current and future applications in injury and trauma research. DESIGN: Literature review and discourse of GIS technology related to injury and trauma research. METHOD: A search of scientific literature databases, ...Community; Public Health; Technology; Internet; Risk Assessment; Wounds and Injuries2007-08
433 Horch, Kenneth W.Differential activation of nerve fibers with magnetic stimulation in humansEarlier observations in our lab had indicated that large, time-varying magnetic fields could elicit action potentials that travel in only one direction in at least some of the myelinated axons in peripheral nerves. The objective of this study was to collect quantitative evidence for magnetically in...Magnetic stimulation; Peripheral nerve; Electromyographic potential; Somatosensory potential2006
434 Digre, Kathleen B.; Blumenthal, Deborah T.; Salzman, Karen L.; Jensen, Randy L.; Dunson, William A.Early pathologic findings and long-term improvement in anti-Ma2-associated encephalitis.A 67-year-old man sequentially developed anti-Ma2-associated paraneoplastic encephalitis (PNE) and contralateral herpes simplex encephalitis (HSE). Brain biopsy 1 month before HSE revealed extensive infiltrates of T cells, B cells, and plasma cells. Most T cells expressed the cytotoxic granule-assoc...Paraneoplastic neurologic disorders; Encephalitis; Neoplasm;Herpes Simplex2006-07-11
435 Asche, Carl V.; Jackson, Kenneth C 2nd; Oderda, Gary M.Economic evaluations in pain management: principles and methods.This paper describes how investigators may design, conduct, and report economic evaluations of pharmacotherapy for pain and symptom management. Because economic evaluation of therapeutic interventions is becoming increasingly important, there is a need for guidance on how economic evaluations can be...Costs and Cost Analysis; Economics, Pharmaceutical2006
436 Schmidt, Meic H.; Couldwell, William T.Far lateral transcondylar transtubercular approach to lesions of the ventral foramen magnum and craniovertebral junctionThe craniovertebral junction, which consists of the lower one third of the clivus, the foramen magnum, and the CI and C2 vertebrae, is a common site for neoplastic, vascular, congenital, and degenerative lesions of the cranial base. The far lateral transcondylar transtubercular approach (commonlyr...Far-lateral; Transcondylar; Transtubercular; Ventral foramen magnum; Craniovertebral junction2007
437 Jorgensen, ErikGenetic screens for synaptic function mutants in the nematode C. elegansThe synapse is the site of a remarkable conversion of electrical signals into chemical signals. This conversion takes place when a depolarizing impulse enters the axon terminal and opens voltage-sensitive calcium channels; calcium then flows into the cell and initiates the fusion of synaptic vesicle...Vesicle; Neurotransmission; Cell1996
438 Nebeker, Jonathan R.; Samore, Matthew HHypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the research on adverse drug events and reports (RADAR) projectOBJECTIVES: We undertook the review of all available cases of hypersensitivity reactions after placement of a drug-eluting stent (DES) and classified potential causes. BACKGROUND: Six months after the approval of the first DES, the Food and Drug Administration (FDA) reported 50 hypersensitivity reac...Drug Hypersensitivity; Coronary Vessels2006
439 Potts, Wayne K.Infection-dependent phenotypes in MHC-congenic mice are not due to MHC: can we trust congenic animals?Congenic strains of mice are assumed to differ only at a single gene or region of the genome. These mice have great importance in evaluating the function of genes. However, their utility depends on the maintenance of this true congenic nature. Although, accumulating evidence suggests that congenic ...Strains; Mutations; Pathogen2004
440 Peay, Wayne J.; Rockoff, Maxine L.Introduction to the JMLA supplement: the NLM 2004 symposium on community-based health information outreachThis paper introduces the Special Supplement to the Journal of the Medical Library Association that documents the proceedings of the Symposium on Community-Based Health Information Outreach held on December 2 and 3, 2004, at the National Library of Medicine (NLM). The goal of the Symposium was to ex...National Library of Medicine (U.S.); NN/LM; RML; National Network of Libraries of Medicine; Regional Medical Libraries; Consumer Health Information; Outreach; Community-based Organziations2005-04
441 Chamberlin, Ralph V.On some genera and species of American MillipedsThe notes and diagnoses in this paper are based primarily upon a small but interesting collection of millipeds recently made in Georgia by Wilton Ivie, and upon specimens in the Field Museum collection chiefly from neighboring sections of the southern states.1943-10-15
442 Capecchi, Mario R.Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy.Although the role of Hox genes in patterning the mammalian body plan has been studied extensively during embryonic and fetal development, relatively little is known concerning Hox gene function in adult animals. Analysis of mice with mutant Hoxa9, Hoxb9, and Hoxd9 genes shows that these paralogous g...Embryonic and Fetal Development; Gene Expression Regulation, Developmental; Genotype; Mice, Knockout1999-01
443 Freire, Juliana; Silva, Claudio T.Provenance for computational tasks: a surveyThe problem of systematically capturing and managing provenance for computational tasks has recently received significant attention because of its relevance to a wide range of domains and applications. The authors give an overview of important concepts related to provenance management, so that poten...Provenance management; Computational tasks2008-05
444 Francis, LeslieRecent developments in genetic diagnosis: some ethical and legal implicationsThis essay outlines some of the ethical complexities genetic technology poses in two areas of decision-making: when to perform genetic testing and what to do with the information gained from genetic testing.Genetic Technology; Genetic Testing; Ethics1986
445 Miller, Jan D.Removal of volatile organic compounds from contaminated water using air-sparged hydrocyclone stripping technologyThe air-sparged hydrocyclone (ASH) technology offers the unique opportunity to achieve efficient removal of volatile organic compounds (VOCs) from contaminated water at a high specific capacity, more than 100 times that of conventional air stripping technologies. VOC stripping is the first applicati...Air-sparged hydrocyclone; Air stripping; Contaminated water1997
446 Bhanu, BirSegmentation of images having unimodal distributionsA gradient relaxation method based on maximizing a criterion function is studied and compared to the nonlinear probabilistic relaxation method for the purpose of segmentation of images having unimodal distributions. Although both methods provide comparable segmentation results, the gradient method h...Gradient relaxation method; Image segmentation; Segmentation algorithm1982
447 Capecchi, Mario R.Selective degradation of abnormal proteins in mammalian tissue culture cells.The degradation rates of several missense mutants of hypoxanthine-guanine phosphoribosyltransferase (EC 2.4.2.8) in mouse L cells are compared to those of the wild-type enzyme. Although the rates of total protein breakdown in the mutant cell lines are identical to that of the parental L cell line, ...Gene Expression Regulation; Mice, Transgenic; Microscopy, Fluorescence1974-12-01
448 Bhanu, BirShape matching of two-dimensional objectsIn this paper we present results in the areas of shape matching of nonoccluded and occluded two-dimensional objects. Shape matching is viewed as a "segment matching" problem. Unlike the previous work, the technique is based on a stochastic labeling procedure which explicitly maximizes a criterion ...Shape matching; Two-dimensional objects; Segment matching1984
449 Parkinson, John StansfieldAn unorthodox sensory adaptation site in the E. coli serine chemoreceptorThe serine chemoreceptor of E. coli contains four canonical methylation sites for sensory adaptation that lie near inter-subunit helix interfaces of the Tsr homodimer. An unexplored fifth methylation site, E502, lies at an intra-subunit helix interface, closest to the HAMP domain that controls input...2014-01-01
450 Beckerle, Mary C.CRP1, a LIM domain protein implicated in muscle differentiation, interacts with α-actininMembers of the cysteine-rich protein (CRP) family are LIM domain proteins that have been implicated in muscle differentiation. One strategy for defining the mechanism by which CRPs potentiate myogenesis is to characterize the repertoire of CRP binding partners.CRP1; Cysteine-rich proteins; Actinin; Protein-protein interactions; LIM domains1997
426 - 450 of 625