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Creator | Title | Description | Subject | Date |
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Fuhrmann, Sabine | Expression of CNTF receptor-alpha in chick violet-sensitive cones with unique morphologic properties. | PURPOSE: Application of ciliary neurotrophic factor (CNTF) can rescue mature photoreceptors from lesion-induced and hereditary degeneration. In the chick retina, expression of the CNTF receptor is present in a subpopulation of photoreceptor cells. The present study was undertaken to identify the CNT... | embryology; cytology | 2004 |
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Baehr, Wolfgang | Identification and light-dependent translocation of a cone-specific antigen, (Cone Arrestin) recognized by monoclonal antibody 7G6 | PURPOSE: To elucidate the antigen recognized by monoclonal antibody (mAb) 7G6, a widely used cone-specific marker. METHODS: 7G6 immunocytochemistry was performed on sections of human, primate, and bovine retina. The antigen was immunoprecipitated from human retinal lysates and purified with protein ... | Cones (Retina); Molecular Sequence Data; Phototransduction | 2003 |
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Bohs, Lynn A. | Phylogeny of the carolinense clade of solanum (Solanaceae) inferred from nuclear and plastid DNA sequences | The large and economically important genus Solanum contains ca. 1,400 species distributed worldwide. One of the 12-14 major clades identified in the genus is the Leptostemonum clade, or the "spiny solanums." Previous molecular phylogenetic studies have identified 14 major clades in the spiny solanum... | | 2014-01-01 |
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Blumenthal, Donald K. | In vivo evaluation of the delivery and efficacy of a sirolimus-laden polymer gel for inhibition of hyperplasia in a porcine model of arteriovenous hemodialysis graft stenosis | Synthetic arteriovenous (AV) hemodialysis grafts are plagued by hyperplasia resulting in occlusion and graft failure yet there are no clinically available preventative treatments. Here the delivery and degradation of a sirolimus-laden polymer gel were monitored in vivo by magnetic resonance imaging ... | | 2012-01-01 |
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Adler, Frederick R. | Mathematical model of a three-stage innate immune response to a pneumococcal lung infection | Pneumococcal pneumonia is a leading cause of death and a major source of human morbidity. The initial immune response plays a central role in determining the course and outcome of pneumococcal disease. We combine bacterial titer measurements from mice infected with Streptococcus pneumoniae with mat... | | 2011 |
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Bastiani, Michael | Role of the cell surface in neuronal pathfinding | Perhaps the organ of the human body that evokes the most astonishment, and yet is the least understood, is our brain. From the coordination of simple movements, to consciousness and thought, the function of the nervous system relies on the establishment of trillions of precise connections among the... | Axon; molecular guidance code; growth cone | 1996 |
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Baehr, Wolfgang | Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis | BACKGROUND: Leber congenital amaurosis (LCA), a heterogeneous early-onset retinal dystrophy, accounts for approximately 15% of inherited congenital blindness. One cause of LCA is loss of the enzyme lecithin:retinol acyl transferase (LRAT), which is required for regeneration of the visual photopigmen... | Disease Models, Animal; Genetic Vectors; Molecular Sequence Data | 2005 |