UScholar Works
 
Filters: Collection: "ir_uspace" Type: "InteractiveResource" Year Start: 2012
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CreatorTitleDescriptionSubjectDate
1 Gerig, GuidoAbnormal brain synchrony in down syndromeDown Syndrome is the most common genetic cause for intellectual disability, yet the pathophysiology of cognitive impairment in Down Syndrome is unknown. We compared fMRI scans of 15 individuals with Down Syndrome to 14 typically developing control subjects while they viewed 50 min of cartoon video c...2013-01-01
2 Hawkes, KristenAge-related decline in ovarian follicle stocks differ between chimpanzee (Pan troglodytes) and humansSimilarity in oldest parturitions in humans and great apes suggests that we maintain ancestral rates of ovarian aging. Consistent with that hypothesis, previous counts of primordial follicles in postmortem ovarian sections from chimpanzees (Pan troglodytes) showed follicle stock decline at the same ...2015-01-01
3 Hawkes, KristenBrief communication: adrenal androgens and aging: female chimpanzees (Pan troglodytes) compared with womenOvarian cycling continues to similar ages in women and chimpanzees yet our nearest living cousins become decrepit during their fertile years and rarely outlive them. Given the importance of estrogen in maintaining physiological systems aside from fertility, similar ovarian aging in humans and chimpa...Dehydroepiandrosterone sulfate; Senescence; Aging rates; Human longevity2013-01-01
4 Gerig, GuidoDiffusion imaging quality control via entropy of principal direction distributionDiffusion MR imaging has received increasing attention in the neuroimaging community, as it yields new insights into the microstructural organization of white matter that are not available with conventional MRI techniques. While the technology has enormous potential, diffusion MRI suffers from a uni...Diffusion magnetic resonance imaging; Diffusion tensor imaging; Quality assessment; Entropy2013-01-01
5 Gerig, GuidoFrontolimbic neural circuitry at 6 months predicts individual differences in joint attention at 9 monthsElucidating the neural basis of joint attention in infancy promises to yield important insights into the development of language and social cognition, and directly informs developmental models of autism. We describe a new method for evaluating responding to joint attention performance in infancy tha...Joint attention; DTI; Amygdala; Uncinate fasciculus; Infancy; Development2013-01-01
6 Hawkes, KristenGrandmothers and the evolution of human longevity: a review of findings and future directionsWomen and female great apes both continue giving birth into their forties, but not beyond. However humans live much longer than other apes do.[1] Even in hunting and gathering societies, where the mortality rate is high, adult life spans average twice those of chimpanzees, which become decrepit duri...Life history evolution; Senescence; Cooperative child rearing; Infant psychology; Male-male competition2013-01-01
7 Hawkes, KristenIncreased longevity evolves from grandmotheringPostmenopausal longevity may have evolved in our lineage when ancestral grandmothers subsidized their daughters' fertility by provisioning grandchildren, but the verbal hypothesis has lacked mathematical support until now. Here, we present a formal simulation in which life spans similar to those of ...Human evolution; Life history; Sexual conflict2012-01-01
8 Gerig, GuidoNetwork inefficiencies in autism spectrum disorder at 24 monthsAutism spectrum disorder (ASD) is a developmental disorder defined by behavioral symptoms that emerge during the first years of life. Associated with these symptoms are differences in the structure of a wide array of brain regions, and in the connectivity between these regions. However, the use of c...2014-01-01
9 Gerig, GuidoNeuroimaging of structural pathology and connectomics in traumatic brain injury: toward personalized outcome predictionRecent contributions to the body of knowledge on traumatic brain injury (TBI) favor the view that multimodal neuroimaging using structural and functionalmagnetic resonance imaging (MRI and fMRI, respectively) as well as diffusion tensor imaging (DTI) has excellent potential to identify novel biomark...Trauma; Neuroimaging; MRI/fMRI; Diffusion tensor; Outcome measures2012-01-01
10 Gerig, GuidoPrenatal isolated mild ventriculomegaly is associated with persistent ventricle enlargement at ages 1 and 2Background-Enlargement of the lateral ventricles is thought to originate from abnormal prenatal brain development and is associated with neurodevelopmental disorders. Fetal isolated mild ventriculomegaly (MVM) is associated with enlargement of lateral ventricle volumes in the neonatal period and dev...Magnetic resonance imaging; Ultrasound; Gray matter; White matter; Cognitive development2012-01-01
11 Gerig, GuidoQuantitative tract-based white matter development from birth to age 2 yearsFew large-scale studies have been done to characterize the normal human brain white matter growth in the first years of life. We investigated white matter maturation patterns in major fiber pathways in a large cohort of healthy young children from birth to age two using diffusion parameters fraction...White matter maturation; Axonal myelination; Early brain development; Diffusion properties; DTI atlas; Fiber tracking; Functional regression analysis2012-01-01
12 Gerton, JordanUsing a sharp metal tip to control the polarization and direction of emission from a quantum dotOptical antennas can be used to manipulate the direction and polarization of radiation from an emitter. Usually, these metallic nanostructures utilize localized plasmon resonances to generate highly directional and strongly polarized emission, which is determined predominantly by the antenna geometr...2014-01-01
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