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| Creator | Title | Description | Subject | Date | ||
|---|---|---|---|---|---|---|
| 1 |
 | Frederick, Jeanne M.; Thulin, Craig; Bernstein, Paul S. | Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye | Uptake, metabolism, and stabilization of xanthophyll carotenoids in the retina are thought to be mediated by specific xanthophyll-binding proteins (XBPs). A membrane-associated XBP was purified from human macula using ion-exchange chromatography followed by gel-exclusion chromatography. Two-dimensio... | Circular Dichroism; Isoelectric Focusing; Macula Lutea; Xanthophylls | 2004 |
| 2 |
 | Bernstein, Paul S. | Transformations of selected carotenoids in plasma, liver, and ocular tissues of humans and in nonprimate animal models | PURPOSE: To determine the stereochemistry of carotenoids in human ocular tissues in comparison with plasma and liver and to elucidate the possible transformations of dietary (3R,3'R,6'R)-lutein and (3R,3'R)-zeaxanthin in the eye. Similarly, to characterize the carotenoid profiles in the eye tissues,... | Chromatography, High Pressure Liquid; Stereoisomerism; Xanthophylls | 2002 |
| 3 |
 | Bernstein, Paul S. | Retinal tubulin binds macular carotenoids | PURPOSE: To investigate the biochemical mechanisms responsible for the specific uptake, concentration, and stabilization of the carotenoids lutein and zeaxanthin in the macula. METHODS: Soluble extracts of bovine retina mixed with radioactive carotenoids were purified by hydrophobic interaction, ion... | Chromatography, Gel; Electrophoresis; Xanthophylls | 1997 |
| 4 |
 | Bernstein, Paul S.; Gellermann, Werner | Raman detection of macular carotenoid pigments in intact human retina | PURPOSE: To develop and test a novel noninvasive optical technique suitable for the objective measurement of macular carotenoid levels in human retina. METHODS: A resonance Raman scattering apparatus was constructed to measure carotenoid levels in flat-mounted human retinas and eyecups and in experi... | Rana pipiens; Spectrum Analysis, Raman; Xanthophylls | 1998 |
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