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Filters: Collection: "ir_uspace" Subject: "Transsphenoidal surgery"
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1 Couldwell, William T.; Apfelbaum, Ronald I.Variations on the standard transsphenoidal approach to the sellar region, with emphasis on the extended approaches and parasellar approaches: surgical experience in 105 casesThe traditional boundaries of the transsphenoidal approach may be expanded to include the region from the cribriform plate of the anterior cranial base to the inferior clivus in the anteroposterior plane, and laterally to expose the cavernous cranial nerves and the optic canal. We review our combin...Transsphenoidal surgery; Chordoma; Craniopharyngioma; Intracranial neoplasm; Meningioma; Pituitary adenoma; Sella turcica; Transsphenoidal craniotomy2004
2 Couldwell, William T.Predictive value of serum prolactin levels measured immediately after transsphenoidal surgeryObject. Prolactin-secreting pituitary adenomas may be managed by surgery, medication, radiotherapy, or observation. The authors reviewed a consecutive series of patients who were followed for at least 5 years after surgery to assess the prognostic significance of preoperative factors (tumor size and...Prolactin; Transsphenoidal surgery; Pituitary adenoma; Prolactinoma; Transsphenoidal approach2002
3 Couldwell, William T.Pituitary gland metastasis from adenocarcinoma of the prostateA case of prostatic carcinoma metastasis to the pituitary gland is reported. The presentation and rarity of such a lesion is addressed. The literature review yielded only isolated case reports of symptomatic brain metastases unassociated with bone disease from adenocarcinoma of the prostate. The man...Prostate; Pituitary gland; Adenocarcinoma; Metastasis; Transsphenoidal surgery1989
4 Couldwell, William T.; Schmidt, Meic H.; MacDonald, Joel D.; Jensen, Randy L.Hypophysial transposition (hypophysopexy) for radiosurgical treatment of pituitary tumors involving the cavernous sinusStereotactic radiosurgery (SRS) is performed with increasing frequency in the treatment of residual or recurrent pituitary adenomas. Its major associated risk in these cases of residual or recurrent pituitary tumor adjacent to normal functional pituitary gland is radiation exposure to the pituitary,...Pituitary tumor; Cavernous sinus; Hypopituitarism; Stereotactic radiosurgery; Transsphenoidal surgery; Pituitary transposition2003
5 Couldwell, William T.Pituitary apoplexy: diagnosis and managementPituitary apoplexy, an uncommon complication of pituitary adenomas, was first decribed in 1898 when pearce Bailey reported hemorrhage into a pituitary adenoma in a 50 year old man with acromegaly. The patient presented with sudden onset of headache, nausea, vomiting, fever, oculomotor palsies, and v...Pituitary Apoplexy; Pituitary adenoma; Transsphenoidal surgery2003
6 Couldwell, William T.Management of pituitary adenomasWe present an overview of the management of pituitary adenomas, with discussions of microanatomy, of diagnostic studies of general neuroendocrine function, and of radiologic evaluation. We discuss the diagnosis of pituitary adenoma and its treatment with sections on null cell, prolactin (PRL)-secre...Pituitary adenoma; Transsphenoidal surgery; Corticotropin; Prolactin; Growth hormone; Transcranial surgery1994
7 Couldwell, William T.Assessment of long-term remission of acromegaly following surgeryObject. The criteria for remission of acromegaly following transsphenoidal adenoma resection are in evolution. In the present study the authors evaluate the utility of predicting long-term remission by reference to a single fasting growth hormone (GH) level on the 1st postoperative day. Methods. A ...Acromegaly; Pituitary adenoma; Transsphenoidal surgery; Growth hormone; Insulin-like growth factor I2003-01-01
8 Couldwell, William T.History and evolution of transsphenoidal surgeryInitial attempts at transcranial approaches to the pituitary gland in the late 1800s and early 1900s resulted in a mortality rate that was generally considered prohibitive. Schloffer suggested the use of a transsphenoidal route as a safer, alternative approach to the sella turcica. He reported the f...Neurosurgical history; Transsphenoidal surgery; Pituitary tumor2001
9 Couldwell, William T.Surgical management of Rathke's cleft cystsRathke's cleft cysts (RCCs) are non-neoplastic cysts that arise from glandular rests of Rathke's cleft in the area of the intermediate lobe of the pituitary gland. Commonly found at autopsy on a microscopic scale, 80% of RCCs occur at the interface between the anterior and posterior lobes of th...Rathke's cleft cyst; Symptomatic; Transnasal-transsphenoidal approach; Transsphenoidal surgery2006
10 Couldwell, William T.Strategies for the management of nonsecreting pituitary adenomasThe two objectives of treating pituitary tumors are: (1) relief of signs and symptoms attributable to mass effect, and (2) correction of hypo - or hypersecretion of adenohypophyseal hormones.7 When nonsecreting tumors are specifically considered, correction of endocrine abnormalities may be of les...Pituitary adenomas; Transsphenoidal surgery1991
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