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CreatorTitleDescriptionSubjectDate
1 Beckerle, Mary C.Activation-dependent redistribution of the adhesion plaque protein, talin, in intact human plateletsTalin is a high molecular weight protein localized at adhesion plaques in fibroblasts. It binds vinculin and integrin and appears to participate in generating a transmembrane connection between the extracellular matrix and the cytoskeleton.Talin1989
2 Beckerle, Mary C.Adhesion plaque protein, talin, is phosphorylated in vivo in chicken embryo fibroblasts exposed to the tumor-promoting phorbol esterTalin is a high molecular weight phosphoprotein that is localized at adhesion plaques. We have found that talin phosphorylation increases 3.0-fold upon exposure of chicken embryo fibroblasts to the tumor-promoting phorbol ester, phorbol 12-myristate 13-acetate.Talin; Vinculin; Chicken embryo fibroblasts1990
3 Beckerle, Mary C.Kindler syndrome protein is regulated by Transforming Growth Factor-β and involved in integrin-mediated adhesionTransforming growth factor-β1 (TGF-β1) contributes to tumor invasion and cancer progression by increasing the motility of tumor cells. To identify genes involved in TGF-β-mediated cell migration, the transcriptional profiles of human mammary epithelial cells (HMEC) treated with TGF-β were compar...Kindler syndrome; Kindlerin; Talin; Focal adhesions; FERM domain2004
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